{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:22:59Z","timestamp":1790396579616,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"51","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,14]],"date-time":"2020-11-14T00:00:00Z","timestamp":1605312000000},"content-version":"vor","delay-in-days":4366,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1074\/jbc.m806232200","type":"journal-article","created":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T00:24:41Z","timestamp":1225153481000},"page":"35745-35755","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"title":["Cholesterol Accumulation by Macrophages Impairs Phagosome Maturation"],"prefix":"10.1016","volume":"283","author":[{"given":"Kassidy K.","family":"Huynh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Gershenzon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Grinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M806232200_bib1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s007950200023","volume":"35","author":"Takahashi","year":"2002","journal-title":"Med. Electron Microsc."},{"key":"10.1074\/jbc.M806232200_bib2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.micron.2005.10.007","volume":"37","author":"Bobryshev","year":"2006","journal-title":"Micron"},{"key":"10.1074\/jbc.M806232200_bib3","first-page":"301","volume":"140","author":"Clinton","year":"1992","journal-title":"Am. J. Pathol."},{"key":"10.1074\/jbc.M806232200_bib4","first-page":"291","volume":"140","author":"Rosenfeld","year":"1992","journal-title":"Am. J. Pathol."},{"key":"10.1074\/jbc.M806232200_bib5","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1080\/07853890310008198","volume":"35","author":"Vainio","year":"2003","journal-title":"Ann. Med."},{"key":"10.1074\/jbc.M806232200_bib6","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1111\/j.1600-0854.2005.00285.x","volume":"6","author":"Wustner","year":"2005","journal-title":"Traffic"},{"key":"10.1074\/jbc.M806232200_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399401003696","volume":"3","author":"Lucas","year":"2001","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1074\/jbc.M806232200_bib8","doi-asserted-by":"crossref","first-page":"17018","DOI":"10.1074\/jbc.272.27.17018","volume":"272","author":"Lange","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib9","doi-asserted-by":"crossref","first-page":"12770","DOI":"10.1074\/jbc.M110399200","volume":"277","author":"Scott","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib10","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1091\/mbc.11.2.467","volume":"11","author":"Bucci","year":"2000","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M806232200_bib11","doi-asserted-by":"crossref","first-page":"4577","DOI":"10.1093\/emboj\/19.17.4577","volume":"19","author":"Gillooly","year":"2000","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M806232200_bib12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/emboj\/21.3.251","volume":"21","author":"Booth","year":"2002","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M806232200_bib13","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0005-2760(90)90201-8","volume":"1045","author":"Liscum","year":"1990","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M806232200_bib14","doi-asserted-by":"crossref","first-page":"11796","DOI":"10.1016\/S0021-9258(18)80136-3","volume":"264","author":"Liscum","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib15","doi-asserted-by":"crossref","first-page":"9653","DOI":"10.1016\/S0021-9258(18)98399-7","volume":"268","author":"Tangirala","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib16","doi-asserted-by":"crossref","first-page":"e851","DOI":"10.1371\/journal.pone.0000851","volume":"2","author":"Sobo","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M806232200_bib17","doi-asserted-by":"crossref","first-page":"30379","DOI":"10.1074\/jbc.273.46.30379","volume":"273","author":"Jahraus","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib18","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0092-8674(91)90316-Q","volume":"64","author":"Gorvel","year":"1991","journal-title":"Cell"},{"key":"10.1074\/jbc.M806232200_bib19","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1128\/MCB.23.7.2501-2514.2003","volume":"23","author":"Vieira","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M806232200_bib20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1083\/jcb.200107069","volume":"155","author":"Vieira","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M806232200_bib21","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1091\/mbc.e04-05-0432","volume":"15","author":"Choudhury","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M806232200_bib22","doi-asserted-by":"crossref","first-page":"17890","DOI":"10.1074\/jbc.M601679200","volume":"281","author":"Ganley","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib23","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/emboj\/21.6.1289","volume":"21","author":"Lebrand","year":"2002","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M806232200_bib24","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1091\/mbc.e06-10-0924","volume":"18","author":"Takahashi","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M806232200_bib25","doi-asserted-by":"crossref","first-page":"6494","DOI":"10.1128\/MCB.23.18.6494-6506.2003","volume":"23","author":"Harrison","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M806232200_bib26","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/emboj\/20.4.683","volume":"20","author":"Cantalupo","year":"2001","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M806232200_bib27","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1159\/000112179","volume":"13","author":"Roff","year":"1991","journal-title":"Dev. Neurosci."},{"key":"10.1074\/jbc.M806232200_bib28","doi-asserted-by":"crossref","first-page":"28436","DOI":"10.1074\/jbc.274.40.28436","volume":"274","author":"Downey","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M806232200_bib29","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1083\/jcb.200106049","volume":"154","author":"Fratti","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M806232200_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/sj.emboj.7601511","volume":"26","author":"Huynh","year":"2007","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M806232200_bib31","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.4049\/jimmunol.178.5.3048","volume":"178","author":"Garcia-Garcia","year":"2007","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M806232200_bib32","doi-asserted-by":"crossref","first-page":"193","DOI":"10.4049\/jimmunol.169.1.193","volume":"169","author":"Kono","year":"2002","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M806232200_bib33","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.bbrc.2005.02.191","volume":"331","author":"Mansfield","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820585189?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820585189?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M806232200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T22:35:30Z","timestamp":1662417330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820585189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":33,"journal-issue":{"issue":"51","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0021925820585189"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m806232200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cholesterol Accumulation by Macrophages Impairs Phagosome Maturation","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M806232200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2008 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}