{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:16:14Z","timestamp":1770059774453,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,4]],"date-time":"2020-10-04T00:00:00Z","timestamp":1601769600000},"content-version":"vor","delay-in-days":4263,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1074\/jbc.m806947200","type":"journal-article","created":{"date-parts":[[2008,11,28]],"date-time":"2008-11-28T01:13:06Z","timestamp":1227834786000},"page":"3976-3984","source":"Crossref","is-referenced-by-count":48,"title":["Structure of Tripeptidyl-peptidase I Provides Insight into the Molecular Basis of Late Infantile Neuronal Ceroid Lipofuscinosis"],"prefix":"10.1016","volume":"284","author":[{"given":"Aritra","family":"Pal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Kraetzner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Gruene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Grapp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mads","family":"Gr\u00f8nborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Urlaub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul R.","family":"Asif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jutta","family":"G\u00e4rtner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George M.","family":"Sheldrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Steinfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M806947200_bib1","first-page":"1794","article-title":"Endocrinology","volume":"103","author":"Doebber","year":"1978"},{"key":"10.1074\/jbc.M806947200_bib2","first-page":"1802","article-title":"Science","volume":"277","author":"Sleat","year":"1997"},{"key":"10.1074\/jbc.M806947200_bib3","first-page":"233","article-title":"Biochim. Biophys. Acta","volume":"1384","author":"Vines","year":"1998"},{"key":"10.1074\/jbc.M806947200_bib4","first-page":"157","article-title":"Biochem. Biophys. Res. Commun","volume":"27","author":"Schechter","year":"1967"},{"key":"10.1074\/jbc.M806947200_bib5","first-page":"145","article-title":"FEBS Lett","volume":"500","author":"Warburton","year":"2001"},{"key":"10.1074\/jbc.M806947200_bib6","first-page":"127","article-title":"J. Biochem. (Tokyo)","volume":"138","author":"Oyama","year":"2005"},{"key":"10.1074\/jbc.M806947200_bib7","first-page":"6559","article-title":"J. Biol. Chem","volume":"281","author":"Tian","year":"2006"},{"key":"10.1074\/jbc.M806947200_bib8","first-page":"904","article-title":"Biochem. Biophys. Res. Commun","volume":"268","author":"Ezaki","year":"2000"},{"key":"10.1074\/jbc.M806947200_bib9","first-page":"2249","article-title":"J. Biol. Chem","volume":"276","author":"Lin","year":"2001"},{"key":"10.1074\/jbc.M806947200_bib10","first-page":"31058","article-title":"J. Biol. Chem","volume":"279","author":"Golabek","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib11","first-page":"2483","article-title":"Hum. Mol. Genet","volume":"13","author":"Steinfeld","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib12","first-page":"12827","article-title":"J. Biol. Chem","volume":"279","author":"Wujek","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib13","first-page":"1511","article-title":"Am. J. Hum. Genet","volume":"64","author":"Sleat","year":"1999"},{"key":"10.1074\/jbc.M806947200_bib14","first-page":"496","article-title":"Biochim. Biophys. Acta","volume":"1429","author":"Rawlings","year":"1999"},{"key":"10.1074\/jbc.M806947200_bib15","first-page":"8","article-title":"BMC Struct. Biol","volume":"3","author":"Wlodawer","year":"2003"},{"key":"10.1074\/jbc.M806947200_bib16","first-page":"21500","article-title":"J. Biol. Chem","volume":"279","author":"Wlodawer","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib17","first-page":"1313","article-title":"Structure (Lond.)","volume":"12","author":"Comellas-Bigler","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib18","first-page":"865","article-title":"Structure (Lond.)","volume":"10","author":"Comellas-Bigler","year":"2002"},{"key":"10.1074\/jbc.M806947200_bib19","first-page":"442","article-title":"Nat. Struct. Biol","volume":"8","author":"Wlodawer","year":"2001"},{"key":"10.1074\/jbc.M806947200_bib20","first-page":"307","article-title":"Methods Enzymol","volume":"276","author":"Otwinowski","year":"1997"},{"key":"10.1074\/jbc.M806947200_bib21","first-page":"1772","article-title":"Acta Crystallogr. Sect. D Biol. Crystallogr","volume":"58","author":"Schneider","year":"2002"},{"key":"10.1074\/jbc.M806947200_bib22","first-page":"112","article-title":"Acta Crystallogr. Sect. A","volume":"64","author":"Sheldrick","year":"2008"},{"key":"10.1074\/jbc.M806947200_bib23","first-page":"2126","article-title":"Acta Crystallogr. Sect. D Biol. Crystallogr","volume":"60","author":"Emsley","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib24","first-page":"240","article-title":"Acta Crystallogr. Sect. D Biol. Crystallogr","volume":"53","author":"Murshudov","year":"1997"},{"key":"10.1074\/jbc.M806947200_bib25","first-page":"C1","article-title":"Glycobiology","volume":"14","author":"Tsiakas","year":"2004"},{"key":"10.1074\/jbc.M806947200_bib26","first-page":"16497","article-title":"J. Biol. Chem","volume":"283","author":"Golabek","year":"2008"},{"key":"10.1074\/jbc.M806947200_bib27","first-page":"673","article-title":"Eur. J. Biochem","volume":"166","author":"Bode","year":"1987"},{"key":"10.1074\/jbc.M806947200_bib28","article-title":"J. Biol. Chem","volume":"284","author":"Guhaniyogi","year":"2009"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819818124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819818124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M806947200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T21:14:48Z","timestamp":1626556488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819818124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0021925819818124"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m806947200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}