{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:31:38Z","timestamp":1787005898087,"version":"build-2736575974"},"reference-count":65,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":574,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI110638"],"award-info":[{"award-number":["R01 AI110638"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P41 GM104603"],"award-info":[{"award-number":["P41 GM104603"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["90066585"],"award-info":[{"award-number":["90066585"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011264","name":"EC | FP7 | FP7 People: Marie-Curie Actions","doi-asserted-by":"publisher","award":["FP7-PEOPLE-2013-ITN-608295"],"award-info":[{"award-number":["FP7-PEOPLE-2013-ITN-608295"]}],"id":[{"id":"10.13039\/100011264","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1074\/jbc.ra118.005179","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T19:45:12Z","timestamp":1544557512000},"page":"1967-1983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites"],"prefix":"10.1016","volume":"294","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8885-3643","authenticated-orcid":false,"given":"Giulia","family":"Bandini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah R.","family":"Leon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin M.","family":"Hoppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Agop-Nersesian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8226-4354","authenticated-orcid":false,"given":"Melanie J.","family":"Shears","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4791-8524","authenticated-orcid":false,"given":"Lara K.","family":"Mahal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7163-0590","authenticated-orcid":false,"given":"Fran\u00e7oise H.","family":"Routier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1594-5122","authenticated-orcid":false,"given":"Catherine E.","family":"Costello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9533-3040","authenticated-orcid":false,"given":"John","family":"Samuelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.RA118.005179_bib1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2471\/BLT.12.111732","article-title":"The global burden of congenital toxoplasmosis: a systematic review","volume":"91","author":"Torgerson","year":"2013","journal-title":"Bull. World Health Organ"},{"key":"10.1074\/jbc.RA118.005179_bib2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.pt.2013.06.001","article-title":"Toxoplasma oocysts as a public health problem","volume":"29","author":"Torrey","year":"2013","journal-title":"Trends Parasitol"},{"key":"10.1074\/jbc.RA118.005179_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ijpara.2003.11.024","article-title":"Use of molecular and ultrastructural markers to evaluate stage conversion of Toxoplasma gondii in both the intermediate and definitive host","volume":"34","author":"Ferguson","year":"2004","journal-title":"Int. J. Parasitol"},{"key":"10.1074\/jbc.RA118.005179_bib4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1462-5822.1999.00023.x","article-title":"Secretion of micronemal proteins is associated with Toxoplasma invasion of host cells","volume":"1","author":"Carruthers","year":"1999","journal-title":"Cell Microbiol"},{"key":"10.1074\/jbc.RA118.005179_bib5","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1046\/j.1365-2958.1999.01174.x","article-title":"Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii","volume":"31","author":"Carruthers","year":"1999","journal-title":"Mol. Microbiol"},{"key":"10.1074\/jbc.RA118.005179_bib6","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1083\/jcb.147.5.937","article-title":"Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites","volume":"147","author":"Kappe","year":"1999","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.005179_bib7","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1074\/mcp.M300123-MCP200","article-title":"Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex","volume":"3","author":"Zhou","year":"2004","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/jbc.RA118.005179_bib8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.molbiopara.2003.12.001","article-title":"Multimerization of the Toxoplasma gondii MIC2 integrin-like A-domain is required for binding to heparin and human cells","volume":"134","author":"Harper","year":"2004","journal-title":"Mol. Biochem. Parasitol"},{"key":"10.1074\/jbc.RA118.005179_bib9","doi-asserted-by":"crossref","first-page":"4005","DOI":"10.1128\/IAI.68.7.4005-4011.2000","article-title":"Toxoplasma gondii uses sulfated proteoglycans for substrate and host cell attachment","volume":"68","author":"Carruthers","year":"2000","journal-title":"Infect. Immun"},{"key":"10.1074\/jbc.RA118.005179_bib10","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1462-5822.2005.00486.x","article-title":"Transepithelial migration of Toxoplasma gondii involves an interaction of intercellular adhesion molecule 1 (ICAM-1) with the parasite adhesin MIC2","volume":"7","author":"Barragan","year":"2005","journal-title":"Cell. Microbiol"},{"key":"10.1074\/jbc.RA118.005179_bib11","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1046\/j.1365-2958.2001.02513.x","article-title":"TgM2AP participates in Toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2","volume":"41","author":"Rabenau","year":"2001","journal-title":"Mol Microbiol"},{"key":"10.1074\/jbc.RA118.005179_bib12","doi-asserted-by":"crossref","first-page":"14346","DOI":"10.1074\/jbc.275.19.14346","article-title":"The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases","volume":"275","author":"Carruthers","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.12688\/wellcomeopenres.11594.2","article-title":"Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo","volume":"2","author":"Gras","year":"2017","journal-title":"Wellcome Open Res"},{"key":"10.1074\/jbc.RA118.005179_bib14","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1093\/emboj\/cdg217","article-title":"Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex","volume":"22","author":"Huynh","year":"2003","journal-title":"EMBO J"},{"key":"10.1074\/jbc.RA118.005179_bib15","doi-asserted-by":"crossref","first-page":"4551","DOI":"10.1091\/mbc.e06-01-0064","article-title":"A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex","volume":"17","author":"Harper","year":"2006","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.005179_bib16","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1074\/jbc.M114.613646","article-title":"Structural basis of Toxoplasma gondii MIC2-associated protein interaction with MIC2","volume":"290","author":"Huynh","year":"2015","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib17","doi-asserted-by":"crossref","first-page":"a009712","DOI":"10.1101\/cshperspect.a009712","article-title":"The thrombospondins","volume":"3","author":"Adams","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol"},{"key":"10.1074\/jbc.RA118.005179_bib18","doi-asserted-by":"crossref","first-page":"6485","DOI":"10.1074\/jbc.M008073200","article-title":"C-Mannosylation and O-fucosylation of the thrombospondin type 1 module","volume":"276","author":"Hofsteenge","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.molcel.2013.03.003","article-title":"C. elegans DPY-19 is a C-mannosyltransferase glycosylating thrombospondin repeats","volume":"50","author":"Buettner","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.RA118.005179_bib20","doi-asserted-by":"crossref","first-page":"13524","DOI":"10.1021\/bi00250a003","article-title":"New type of linkage between a carbohydrate and a protein: C-glycosylation of a specific tryptophan residue in human RNase Us","volume":"33","author":"Hofsteenge","year":"1994","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.RA118.005179_bib21","doi-asserted-by":"crossref","first-page":"e1005606","DOI":"10.1371\/journal.ppat.1005606","article-title":"Interrogating the plasmodium sporozoite surface: identification of surface-exposed proteins and demonstration of glycosylation on CSP and TRAP by mass spectrometry-based proteomics","volume":"12","author":"Swearingen","year":"2016","journal-title":"PLoS Pathog"},{"key":"10.1074\/jbc.RA118.005179_bib22","doi-asserted-by":"crossref","first-page":"9393","DOI":"10.1074\/jbc.M511975200","article-title":"Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats","volume":"281","author":"Luo","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib23","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.cub.2014.11.049","article-title":"Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism","volume":"25","author":"Vasudevan","year":"2015","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.RA118.005179_bib24","doi-asserted-by":"crossref","first-page":"36742","DOI":"10.1074\/jbc.M605912200","article-title":"Identification and characterization of a \u03b21,3-glucosyltransferase that synthesizes the Glc-\u03b21,3-Fuc disaccharide on thrombospondin type 1 repeats","volume":"281","author":"Kozma","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib25","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/glycob\/cwy013","article-title":"Apicomplexan C-mannosyltransferases modify thrombospondin type I-containing adhesins of the TRAP family","volume":"28","author":"Hoppe","year":"2018","journal-title":"Glycobiology"},{"key":"10.1074\/jbc.RA118.005179_bib26","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1091\/mbc.9.2.291","article-title":"Protein C-mannosylation is enzyme-catalysed and uses dolichyl-phosphate-mannose as a precursor","volume":"9","author":"Doucey","year":"1998","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.005179_bib27","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1073\/pnas.1613165114","article-title":"Distinct C-mannosylation of netrin receptor thrombospondin type 1 repeats by mammalian DPY19L1 and DPY19L3","volume":"114","author":"Shcherbakova","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.005179_bib28","doi-asserted-by":"crossref","first-page":"17024","DOI":"10.1074\/jbc.M701065200","article-title":"O-Fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1\/punctin-1 regulates secretion: implications for the ADAMTS superfamily","volume":"282","author":"Wang","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib29","doi-asserted-by":"crossref","first-page":"30004","DOI":"10.1074\/jbc.M109.038059","article-title":"Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1\/punctin-1 by C-mannosylation of tryptophan","volume":"284","author":"Wang","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib30","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gene.2015.22","article-title":"A conserved sugar bridge connected to the WSXWS motif has an important role for transport of IL-21R to the plasma membrane","volume":"16","author":"Siupka","year":"2015","journal-title":"Genes Immun"},{"key":"10.1074\/jbc.RA118.005179_bib31","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ydbio.2016.05.038","article-title":"Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion","volume":"416","author":"Benz","year":"2016","journal-title":"Dev. Biol"},{"key":"10.1074\/jbc.RA118.005179_bib32","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/s41467-017-00571-y","article-title":"Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts","volume":"8","author":"Lopaticki","year":"2017","journal-title":"Nat Commun"},{"key":"10.1074\/jbc.RA118.005179_bib33","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s10719-015-9633-3","article-title":"A review of methods for interpretation of glycopeptide tandem mass spectral data","volume":"33","author":"Hu","year":"2016","journal-title":"Glycoconj. J"},{"key":"10.1074\/jbc.RA118.005179_bib34","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/mas.20337","article-title":"Mass spectrometric glycan rearrangements","volume":"30","author":"Wuhrer","year":"2011","journal-title":"Mass Spectrom. Rev"},{"key":"10.1074\/jbc.RA118.005179_bib35","doi-asserted-by":"crossref","first-page":"D490","DOI":"10.1093\/nar\/gkt1178","article-title":"The carbohydrate-active enzymes database (CAZy) in 2013","volume":"42","author":"Lombard","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.RA118.005179_bib36","doi-asserted-by":"crossref","first-page":"1C","DOI":"10.1093\/glycob\/cwg113","article-title":"A new superfamily of protein-O-fucosyltransferases, 2-fucosyltransferases, and 6-fucosyltransferases: phylogeny and identification of conserved peptide motifs","volume":"13","author":"Martinez-Duncker","year":"2003","journal-title":"Glycobiology"},{"key":"10.1074\/jbc.RA118.005179_bib37","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nchembio.2019","article-title":"A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2","volume":"12","author":"Valero-Gonz\u00e1lez","year":"2016","journal-title":"Nat. Chem. Biol"},{"key":"10.1074\/jbc.RA118.005179_bib38","doi-asserted-by":"crossref","first-page":"e100450","DOI":"10.1371\/journal.pone.0100450","article-title":"Efficient genome engineering of Toxoplasma gondii using CRISPR\/Cas9","volume":"9","author":"Sidik","year":"2014","journal-title":"PLoS One"},{"key":"10.1074\/jbc.RA118.005179_bib39","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1128\/EC.00358-08","article-title":"Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80","volume":"8","author":"Huynh","year":"2009","journal-title":"Eukaryot. Cell"},{"key":"10.1074\/jbc.RA118.005179_bib40","first-page":"3320","article-title":"Dynamics of the Toxoplasma gondii inner membrane complex","volume":"127","author":"Ouologuem","year":"2014","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA118.005179_bib41","doi-asserted-by":"crossref","first-page":"W389","DOI":"10.1093\/nar\/gkv332","article-title":"JPred4: a protein secondary structure prediction server","volume":"43","author":"Drozdetskiy","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.RA118.005179_bib42","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/nature24464","article-title":"Structural basis of nucleotide sugar transport across the Golgi membrane","volume":"551","author":"Parker","year":"2017","journal-title":"Nature"},{"key":"10.1074\/jbc.RA118.005179_bib43","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1128\/IAI.73.2.695-702.2005","article-title":"Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains","volume":"73","author":"Saeij","year":"2005","journal-title":"Infect. Immun"},{"key":"10.1074\/jbc.RA118.005179_bib44","doi-asserted-by":"crossref","first-page":"11567","DOI":"10.1073\/pnas.1613653113","article-title":"O-Fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii","volume":"113","author":"Bandini","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.005179_bib45","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.cell.2016.08.019","article-title":"A Genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes","volume":"166","author":"Sidik","year":"2016","journal-title":"Cell"},{"key":"10.1074\/jbc.RA118.005179_bib46","doi-asserted-by":"crossref","first-page":"11033","DOI":"10.1093\/nar\/gkw880","article-title":"2016 update of the PRIDE database and its related tools","volume":"44","author":"Vizca\u00edno","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.RA118.005179_bib47","doi-asserted-by":"crossref","first-page":"D553","DOI":"10.1093\/nar\/gkm981","article-title":"ToxoDB: an integrated Toxoplasma gondii database resource","volume":"36","author":"Gajria","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.RA118.005179_bib48","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1074\/jbc.RA118.006072","article-title":"CRISPR\/Cas9 and glycomics tools for Toxoplasma glycobiology","volume":"294","author":"Gas-Pascual","year":"2019","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib49","doi-asserted-by":"crossref","first-page":"40338","DOI":"10.1074\/jbc.M107849200","article-title":"Modification of epidermal growth factor-like repeats with O-fucose: molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase","volume":"276","author":"Wang","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib50","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.1365-2958.2010.07255.x","article-title":"Toxoplasma gondii transmembrane microneme proteins and their modular design","volume":"77","author":"Sheiner","year":"2010","journal-title":"Mol Microbiol"},{"key":"10.1074\/jbc.RA118.005179_bib51","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.1074\/jbc.M109.016964","article-title":"Two pathways for importing GDP-fucose into the endoplasmic reticulum lumen function redundantly in the O-fucosylation of Notch in Drosophila","volume":"285","author":"Ishikawa","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib52","doi-asserted-by":"crossref","first-page":"27230","DOI":"10.1074\/jbc.M504783200","article-title":"The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine","volume":"280","author":"Ashikov","year":"2005","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib53","doi-asserted-by":"crossref","first-page":"36245","DOI":"10.1074\/jbc.M110.126003","article-title":"Slc35c2 promotes Notch1 fucosylation and is required for optimal Notch signaling in mammalian cells","volume":"285","author":"Lu","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib54","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s10719-014-9556-4","article-title":"Novel roles for O-linked glycans in protein folding","volume":"31","author":"Vasudevan","year":"2014","journal-title":"Glycoconj. J"},{"key":"10.1074\/jbc.RA118.005179_bib55","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00012-16","article-title":"A Toxoplasma gondii ortholog of Plasmodium GAMA contributes to parasite attachment and cell invasion","author":"Huynh","year":"2016","journal-title":"mSphere"},{"key":"10.1074\/jbc.RA118.005179_bib56","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1074\/jbc.RA118.005357","article-title":"Protein O-fucosyltransferase 2-mediated O-glycosylation of MIC2 is dispensable for Toxoplasma gondii tachyzoites","volume":"294","author":"Khurana","year":"2019","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib57","doi-asserted-by":"crossref","first-page":"18644","DOI":"10.1074\/jbc.M117.809301","article-title":"Characterization of a cytoplasmic glucosyltransferase that extends the core trisaccharide of the Toxoplasma Skp1 E3 ubiquitin ligase subunit","volume":"292","author":"Rahman","year":"2017","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib58","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1074\/jbc.M115.703751","article-title":"The E3 ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development","volume":"291","author":"Rahman","year":"2016","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.005179_bib59","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/msb.2011.75","article-title":"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega","volume":"7","author":"Sievers","year":"2011","journal-title":"Mol. Syst. Biol"},{"key":"10.1074\/jbc.RA118.005179_bib60","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1093\/bioinformatics\/btp033","article-title":"Jalview Version 2\u2013a multiple sequence alignment editor and analysis workbench","volume":"25","author":"Waterhouse","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1074\/jbc.RA118.005179_bib61","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0091-679X(08)61845-2","article-title":"Molecular Tools for Genetic Dissection of the Protozoan Parasite Toxoplasma gondii","volume":"45","author":"Roos","year":"1994","journal-title":"Methods Cell Biol"},{"key":"10.1074\/jbc.RA118.005179_bib62","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1074\/jbc.RA118.005179_bib63","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1002\/cbic.200700225","article-title":"Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold","volume":"8","author":"Kaltgrad","year":"2007","journal-title":"Chembiochem"},{"key":"10.1074\/jbc.RA118.005179_bib64","doi-asserted-by":"crossref","first-page":"5265","DOI":"10.1091\/mbc.e06-08-0702","article-title":"GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat","volume":"17","author":"G\u00fcther","year":"2006","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.005179_bib65","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1006\/abio.1997.9994","article-title":"\u03b2-Elimination of O-glycans from glycoproteins transferred to immobilon P membranes: method and some applications","volume":"253","author":"Duk","year":"1997","journal-title":"Anal. Biochem"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820368435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820368435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.RA118.005179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T02:40:41Z","timestamp":1720838441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820368435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":65,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S0021925820368435"],"URL":"https:\/\/doi.org\/10.1074\/jbc.ra118.005179","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/382515","asserted-by":"object"}]},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.RA118.005179","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Bandini et al.","name":"copyright","label":"Copyright"}]}}