{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T23:31:50Z","timestamp":1786318310343,"version":"build-2736575974"},"reference-count":64,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":549,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["1R01 EY08123"],"award-info":[{"award-number":["1R01 EY08123"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["1P30 EY014800\u2013039003"],"award-info":[{"award-number":["1P30 EY014800\u2013039003"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["1R01EY019298"],"award-info":[{"award-number":["1R01EY019298"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1074\/jbc.ra118.006371","type":"journal-article","created":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T01:46:44Z","timestamp":1547603204000},"page":"3957-3973","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors"],"prefix":"10.1016","volume":"294","author":[{"given":"Guoxin","family":"Ying","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne M.","family":"Frederick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Baehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.RA118.006371_bib1","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1073\/pnas.032658599","article-title":"The origin of the eukaryotic cell: A genomic investigation","volume":"99","author":"Hartman","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib2","doi-asserted-by":"crossref","first-page":"18746","DOI":"10.1074\/jbc.M513667200","article-title":"The structure of the human centrin 2-xeroderma pigmentosum group C protein complex","volume":"281","author":"Thompson","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.006371_bib3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0248-4900(92)90442-4","article-title":"Centrin is a component of the pericentriolar lattice","volume":"76","author":"Baron","year":"1992","journal-title":"Biol. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib4","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1083\/jcb.107.6.2669","article-title":"Identification and localization of a novel, cytoskeletal, centrosome-associated protein in PtK2 cells","volume":"107","author":"Baron","year":"1988","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib5","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1242\/jcs.109.13.3089","article-title":"Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles","volume":"109","author":"Paoletti","year":"1996","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA118.006371_bib6","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/jcp.21226","article-title":"A mechanistic view on the evolutionary origin for centrin-based control of centriole duplication","volume":"213","author":"Salisbury","year":"2007","journal-title":"J. Cell. Physiol"},{"key":"10.1074\/jbc.RA118.006371_bib7","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1007\/s00018-012-0961-1","article-title":"Such small hands: The roles of centrins\/caltractins in the centriole and in genome maintenance","volume":"69","author":"Dantas","year":"2012","journal-title":"Cell. Mol. Life Sci"},{"key":"10.1074\/jbc.RA118.006371_bib8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0962-8924(95)80011-5","article-title":"In search of a function for centrins","volume":"5","author":"Schiebel","year":"1995","journal-title":"Trends Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib9","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1083\/jcb.201012093","article-title":"Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins","volume":"193","author":"Dantas","year":"2011","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib10","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/S0960-9822(02)01019-9","article-title":"Centrin-2 is required for centriole duplication in mammalian cells","volume":"12","author":"Salisbury","year":"2002","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.RA118.006371_bib11","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.devcel.2007.07.004","article-title":"Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle","volume":"13","author":"Strnad","year":"2007","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib12","doi-asserted-by":"crossref","first-page":"4361","DOI":"10.1091\/mbc.e10-04-0298","article-title":"Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly","volume":"21","author":"Yang","year":"2010","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib13","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.devcel.2007.07.002","article-title":"Plk4-induced centriole biogenesis in human cells","volume":"13","author":"Kleylein-Sohn","year":"2007","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib14","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1083\/jcb.148.3.405","article-title":"A role for centrin 3 in centrosome reproduction","volume":"148","author":"Middendorp","year":"2000","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib15","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1083\/jcb.201411070","article-title":"Centrin2 regulates CP110 removal in primary cilium formation","volume":"208","author":"Prosser","year":"2015","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib16","doi-asserted-by":"crossref","first-page":"3964","DOI":"10.4161\/cc.10.22.18150","article-title":"Centrin depletion causes cyst formation and other ciliopathy-related phenotypes in zebrafish","volume":"10","author":"Delaval","year":"2011","journal-title":"Cell Cycle"},{"key":"10.1074\/jbc.RA118.006371_bib17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s11033-006-9004-z","article-title":"Centrin isoforms in mammals: Relation to calmodulin","volume":"33","author":"Friedberg","year":"2006","journal-title":"Mol. Biol. Rep"},{"key":"10.1074\/jbc.RA118.006371_bib18","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-0-387-74021-8_10","article-title":"Origin and evolution of the centrosome","volume":"607","author":"Bornens","year":"2007","journal-title":"Adv. Exp. Med. Biol"},{"key":"10.1074\/jbc.RA118.006371_bib19","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1006\/geno.1999.5880","article-title":"Testis-specific murine centrin, Cetn1: Genomic characterization and evidence for retroposition of a gene encoding a centrosome protein","volume":"60","author":"Hart","year":"1999","journal-title":"Genomics"},{"key":"10.1074\/jbc.RA118.006371_bib20","doi-asserted-by":"crossref","first-page":"9141","DOI":"10.1073\/pnas.94.17.9141","article-title":"Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene","volume":"94","author":"Middendorp","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib21","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1091\/mbc.e02-11-0709","article-title":"Centrin4p, a novel mammalian centrin specifically expressed in ciliated cells","volume":"14","author":"Gavet","year":"2003","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib22","first-page":"3204","article-title":"Germline deletion of Cetn1 causes infertility in male mice","volume":"126","author":"Avasthi","year":"2013","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA118.006371_bib23","doi-asserted-by":"crossref","first-page":"6377","DOI":"10.1523\/JNEUROSCI.0067-14.2014","article-title":"Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity","volume":"34","author":"Ying","year":"2014","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.RA118.006371_bib24","doi-asserted-by":"crossref","first-page":"51472","DOI":"10.1074\/jbc.M406770200","article-title":"Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells","volume":"279","author":"Giessl","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.006371_bib25","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1128\/MCB.22.7.2194-2203.2002","article-title":"Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells","volume":"22","author":"Pulverm\u00fcller","year":"2002","journal-title":"Mol. Cell. Biol"},{"key":"10.1074\/jbc.RA118.006371_bib26","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1083\/jcb.201712117","article-title":"SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium","volume":"217","author":"Dharmat","year":"2018","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib27","doi-asserted-by":"crossref","first-page":"6427","DOI":"10.1523\/JNEUROSCI.1335-04.2004","article-title":"The retinitis pigmentosa 1 protein is a photoreceptor microtubule-associated protein","volume":"24","author":"Liu","year":"2004","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.RA118.006371_bib28","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1167\/iovs.03-0410","article-title":"RP1 is required for the correct stacking of outer segment discs","volume":"44","author":"Liu","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib29","doi-asserted-by":"crossref","first-page":"5698","DOI":"10.1073\/pnas.042122399","article-title":"Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene","volume":"99","author":"Gao","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib30","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.preteyeres.2015.12.002","article-title":"PRPH2\/RDS and ROM-1: Historical context, current views and future considerations","volume":"52","author":"Stuck","year":"2016","journal-title":"Prog. Retin. Eye Res"},{"key":"10.1074\/jbc.RA118.006371_bib31","first-page":"2908","article-title":"Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice","volume":"118","author":"Yang","year":"2008","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.RA118.006371_bib32","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1523\/JNEUROSCI.2964-17.2018","article-title":"C8ORF37 is required for photoreceptor outer segment disc morphogenesis by maintaining outer segment membrane protein homeostasis","volume":"38","author":"Sharif","year":"2018","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.RA118.006371_bib33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1083\/jcb.200911095","article-title":"Intraflagellar transport molecules in ciliary and nonciliary cells of the retina","volume":"189","author":"Sedmak","year":"2010","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib34","doi-asserted-by":"crossref","first-page":"5512","DOI":"10.1073\/pnas.83.15.5512","article-title":"Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins","volume":"83","author":"Baum","year":"1986","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib35","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0960-9822(01)00094-X","article-title":"Kinetics and regulation of de novo centriole assembly: Implications for the mechanism of centriole duplication","volume":"11","author":"Marshall","year":"2001","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.RA118.006371_bib36","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1242\/jcs.00497","article-title":"Centrin deficiency in Chlamydomonas causes defects in basal body replication, segregation and maturation","volume":"116","author":"Koblenz","year":"2003","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA118.006371_bib37","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.gde.2012.04.006","article-title":"The ciliopathies: a transitional model into systems biology of human genetic disease","volume":"22","author":"Davis","year":"2012","journal-title":"Curr. Opin. Genet. Dev"},{"key":"10.1074\/jbc.RA118.006371_bib38","doi-asserted-by":"crossref","first-page":"20334","DOI":"10.1074\/jbc.M113.464792","article-title":"Mice lacking \u03b1-tubulin acetyltransferase 1 are viable but display \u03b1-tubulin acetylation deficiency and dentate gyrus distortion","volume":"288","author":"Kim","year":"2013","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.006371_bib39","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1126\/science.aai8764","article-title":"Microtubules acquire resistance from mechanical breakage through intralumenal acetylation","volume":"356","author":"Xu","year":"2017","journal-title":"Science"},{"key":"10.1074\/jbc.RA118.006371_bib40","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/ncb3481","article-title":"Tubulin acetylation protects long-lived microtubules against mechanical ageing","volume":"19","author":"Portran","year":"2017","journal-title":"Nat. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib41","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1091\/mbc.e08-09-0909","article-title":"Anterograde microtubule transport drives microtubule bending in LLC-PK1 epithelial cells","volume":"20","author":"Bicek","year":"2009","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.RA118.006371_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaf0659","article-title":"Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes","volume":"352","author":"Robison","year":"2016","journal-title":"Science"},{"key":"10.1074\/jbc.RA118.006371_bib43","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1083\/jcb.200601060","article-title":"Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement","volume":"173","author":"Brangwynne","year":"2006","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA118.006371_bib44","doi-asserted-by":"crossref","first-page":"21517","DOI":"10.1073\/pnas.1013728107","article-title":"The major \u03b1-tubulin K40 acetyltransferase \u03b1TAT1 promotes rapid ciliogenesis and efficient mechanosensation","volume":"107","author":"Shida","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib45","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.cell.2007.04.035","article-title":"HEF1-dependent Aurora A activation induces disassembly of the primary cilium","volume":"129","author":"Pugacheva","year":"2007","journal-title":"Cell"},{"key":"10.1074\/jbc.RA118.006371_bib46","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1093\/hmg\/ddu573","article-title":"Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina","volume":"24","author":"Eblimit","year":"2015","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA118.006371_bib47","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1093\/hmg\/ddu242","article-title":"Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration","volume":"23","author":"Karlstetter","year":"2014","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA118.006371_bib48","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1167\/iovs.12-9662","article-title":"The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL\/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes","volume":"53","author":"Mattapallil","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib49","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/nprot.2008.70","article-title":"A protocol for constructing gene targeting vectors: Generating knockout mice for the cadherin family and beyond","volume":"3","author":"Wu","year":"2008","journal-title":"Nat. Protoc"},{"key":"10.1074\/jbc.RA118.006371_bib50","doi-asserted-by":"crossref","first-page":"52","DOI":"10.2144\/00291bm09","article-title":"Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and Tris (HotSHOT)","volume":"29","author":"Truett","year":"2000","journal-title":"Biotechniques"},{"key":"10.1074\/jbc.RA118.006371_bib51","first-page":"1138","article-title":"Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival","volume":"127","author":"Coleman","year":"2014","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA118.006371_bib52","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0161236","article-title":"Small GTPases Rab8a and Rab11a are dispensable for rhodopsin transport in mouse photoreceptors","volume":"11","author":"Ying","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.RA118.006371_bib53","first-page":"462","article-title":"Mouse cone arrestin expression pattern: Light induced translocation in cone photoreceptors","volume":"8","author":"Zhu","year":"2002","journal-title":"Mol. Vis"},{"key":"10.1074\/jbc.RA118.006371_bib54","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1093\/hmg\/ddl107","article-title":"In-frame deletion in a novel centrosomal\/ciliary protein CEP290\/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse","volume":"15","author":"Chang","year":"2006","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA118.006371_bib55","doi-asserted-by":"crossref","first-page":"3649","DOI":"10.1073\/pnas.97.7.3649","article-title":"A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3)","volume":"97","author":"Hong","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib56","doi-asserted-by":"crossref","first-page":"12091","DOI":"10.1074\/jbc.M009351200","article-title":"Retinitis pigmentosa GTPase regulator (RPGR)-interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium","volume":"276","author":"Hong","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA118.006371_bib57","doi-asserted-by":"crossref","first-page":"6544","DOI":"10.1021\/bi00321a041","article-title":"Localization of binding sites for carboxyl terminal specific anti-rhodopsin monoclonal antibodies using synthetic peptides","volume":"23","author":"MacKenzie","year":"1984","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1074\/jbc.RA118.006371_bib58","first-page":"352","article-title":"Molecular cloning, membrane topology, and localization of bovine rom-1 in rod and cone photoreceptor cells","volume":"37","author":"Moritz","year":"1996","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib59","first-page":"50","article-title":"Peripherin: A rim-specific membrane protein of rod outer segment discs","volume":"28","author":"Molday","year":"1987","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib60","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1167\/iovs.06-0086","article-title":"Light-driven cone arrestin translocation in cones of postnatal guanylate cyclase-1 knockout mouse retina treated with AAV-GC1","volume":"47","author":"Haire","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib61","first-page":"22","article-title":"Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors","volume":"43","author":"Liu","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA118.006371_bib62","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1172\/JCI60981","article-title":"Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis","volume":"122","author":"Rachel","year":"2012","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.RA118.006371_bib63","doi-asserted-by":"crossref","first-page":"12425","DOI":"10.1073\/pnas.94.23.12425","article-title":"Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells","volume":"94","author":"Weigmann","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA118.006371_bib64","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.200107108","article-title":"The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance","volume":"157","author":"Pazour","year":"2002","journal-title":"J. Cell Biol"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820418095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820418095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.RA118.006371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T11:32:45Z","timestamp":1641295965000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820418095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":64,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0021925820418095"],"URL":"https:\/\/doi.org\/10.1074\/jbc.ra118.006371","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.RA118.006371","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Ying et al.","name":"copyright","label":"Copyright"}]}}