{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:19:04Z","timestamp":1790705944032,"version":"4.1.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"50","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":274,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["R01-EY022616"],"award-info":[{"award-number":["R01-EY022616"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["R21-EY027431"],"award-info":[{"award-number":["R21-EY027431"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1074\/jbc.ra119.009712","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T21:44:17Z","timestamp":1573076657000},"page":"19119-19136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors"],"prefix":"10.1016","volume":"294","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4989-0975","authenticated-orcid":false,"given":"Poppy","family":"Datta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Hendrickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Brendalen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avri","family":"Ruffcorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7908-3210","authenticated-orcid":false,"given":"Seongjin","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.RA119.009712_bib1","doi-asserted-by":"crossref","first-page":"R75","DOI":"10.1093\/hmg\/ddx163","article-title":"Photoreceptor outer segment as a sink for membrane proteins: hypothesis and implications in retinal ciliopathies","volume":"26","author":"Seo","year":"2017","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1083\/jcb.33.1.61","article-title":"The renewal of photoreceptor cell outer segments","volume":"33","author":"Young","year":"1967","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.preteyeres.2018.12.004","article-title":"Insights into photoreceptor ciliogenesis revealed by animal models","volume":"71","author":"Baehr","year":"2019","journal-title":"Prog. Retin. Eye Res"},{"key":"10.1074\/jbc.RA119.009712_bib4","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1083\/jcb.201006105","article-title":"CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content","volume":"190","author":"Craige","year":"2010","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib5","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1083\/jcb.201012116","article-title":"MKS and NPHP modules cooperate to establish basal body\/transition zone membrane associations and ciliary gate function during ciliogenesis","volume":"192","author":"Williams","year":"2011","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib6","doi-asserted-by":"crossref","first-page":"e1002416","DOI":"10.1371\/journal.pbio.1002416","article-title":"MKS5 and CEP290 dependent assembly pathway of the ciliary transition zone","volume":"14","author":"Li","year":"2016","journal-title":"PLos Biol"},{"key":"10.1074\/jbc.RA119.009712_bib7","doi-asserted-by":"crossref","first-page":"3796","DOI":"10.1093\/hmg\/ddn277","article-title":"CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium","volume":"17","author":"Kim","year":"2008","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib8","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/ng.891","article-title":"A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition","volume":"43","author":"Garcia-Gonzalo","year":"2011","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib9","doi-asserted-by":"crossref","first-page":"14096","DOI":"10.1038\/srep14096","article-title":"Super-resolution pattern recognition reveals the architectural map of the ciliary transition zone","volume":"5","author":"Yang","year":"2015","journal-title":"Sci. Rep"},{"key":"10.1074\/jbc.RA119.009712_bib10","doi-asserted-by":"crossref","first-page":"e97791","DOI":"10.15252\/embj.201797791","article-title":"Cell type-specific regulation of ciliary transition zone assembly in vertebrates","volume":"37","author":"Wiegering","year":"2018","journal-title":"EMBO J"},{"key":"10.1074\/jbc.RA119.009712_bib11","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.celrep.2017.06.045","article-title":"In vitro modeling using ciliopathy-patient\u2013derived cells reveals distinct cilia dysfunctions caused by CEP290 mutations","volume":"20","author":"Shimada","year":"2017","journal-title":"Cell Rep"},{"key":"10.1074\/jbc.RA119.009712_bib12","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/embor.2012.73","article-title":"The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization","volume":"13","author":"Reiter","year":"2012","journal-title":"EMBO Rep"},{"key":"10.1074\/jbc.RA119.009712_bib13","doi-asserted-by":"crossref","first-page":"R928","DOI":"10.1016\/j.cub.2010.09.058","article-title":"Ciliary trafficking: CEP290 guards a gated community","volume":"20","author":"Betleja","year":"2010","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.RA119.009712_bib14","doi-asserted-by":"crossref","first-page":"a028134","DOI":"10.1101\/cshperspect.a028134","article-title":"Open sesame: how transition fibers and the transition zone control ciliary composition","volume":"9","author":"Garcia-Gonzalo","year":"2017","journal-title":"Cold Spring Harb. Perspect. Biol"},{"key":"10.1074\/jbc.RA119.009712_bib15","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1093\/hmg\/ddl107","article-title":"In-frame deletion in a novel centrosomal\/ciliary protein CEP290\/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse","volume":"15","author":"Chang","year":"2006","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib16","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1093\/hmg\/ddv123","article-title":"CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies","volume":"24","author":"Rachel","year":"2015","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib17","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1086\/507318","article-title":"Mutations in the CEP290 (NPHP6) gene are a frequent cause of Leber congenital amaurosis","volume":"79","author":"den Hollander","year":"2006","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib18","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/ng1786","article-title":"The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4","volume":"38","author":"Sayer","year":"2006","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib19","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1086\/519494","article-title":"Pleiotropic effects of CEP290 (NPHP6) mutations extend to Meckel syndrome","volume":"81","author":"Baala","year":"2007","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib20","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1002\/humu.20565","article-title":"Centrosomal-ciliary gene CEP290\/NPHP6 mutations result in blindness with unexpected sparing of photoreceptors and visual brain: implications for therapy of Leber congenital amaurosis","volume":"28","author":"Cideciyan","year":"2007","journal-title":"Hum. Mutat"},{"key":"10.1074\/jbc.RA119.009712_bib21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/humu.20614","article-title":"Mutations of the CEP290 gene encoding a centrosomal protein cause Meckel-Gruber syndrome","volume":"29","author":"Frank","year":"2008","journal-title":"Hum. Mutat"},{"key":"10.1074\/jbc.RA119.009712_bib22","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.preteyeres.2008.05.003","article-title":"Leber congenital amaurosis: genes, proteins and disease mechanisms","volume":"27","author":"den Hollander","year":"2008","journal-title":"Prog. Retin. Eye Res"},{"key":"10.1074\/jbc.RA119.009712_bib23","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1002\/humu.21337","article-title":"CEP290, a gene with many faces: mutation overview and presentation of CEP290 base","volume":"31","author":"Coppieters","year":"2010","journal-title":"Hum. Mutat"},{"key":"10.1074\/jbc.RA119.009712_bib24","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1172\/JCI60981","article-title":"Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis","volume":"122","author":"Rachel","year":"2012","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.RA119.009712_bib25","doi-asserted-by":"crossref","first-page":"e0213960","DOI":"10.1371\/journal.pone.0213960","article-title":"Ciliary genes arl13b, ahi1 and cc2d2a differentially modify expression of visual acuity phenotypes but do not enhance retinal degeneration due to mutation of cep290 in zebrafish","volume":"14","author":"Lessieur","year":"2019","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.RA119.009712_bib26","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1083\/jcb.200806009","article-title":"The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors","volume":"183","author":"Baker","year":"2008","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib27","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/nm.2380","article-title":"Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome","volume":"17","author":"Lancaster","year":"2011","journal-title":"Nat. Med"},{"key":"10.1074\/jbc.RA119.009712_bib28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/gene.20097","article-title":"Rhodopsin-iCre transgenic mouse line for Cre-mediated rod-specific gene targeting","volume":"41","author":"Li","year":"2005","journal-title":"Genesis"},{"key":"10.1074\/jbc.RA119.009712_bib29","doi-asserted-by":"crossref","first-page":"3646","DOI":"10.1167\/iovs.09-5074","article-title":"A novel nonsense mutation in CEP290 induces exon skipping and leads to a relatively mild retinal phenotype","volume":"51","author":"Littink","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib30","doi-asserted-by":"crossref","first-page":"291ra97","DOI":"10.1126\/scitranslmed.aaa5370","article-title":"Basal exon skipping and genetic pleiotropy: a predictive model of disease pathogenesis","volume":"7","author":"Drivas","year":"2015","journal-title":"Sci. Transl. Med"},{"key":"10.1074\/jbc.RA119.009712_bib31","doi-asserted-by":"crossref","first-page":"E208","DOI":"10.3390\/genes8080208","article-title":"A rare form of retinal dystrophy caused by hypomorphic nonsense mutations in CEP290","volume":"8","author":"Roosing","year":"2017","journal-title":"Genes"},{"key":"10.1074\/jbc.RA119.009712_bib32","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1093\/hmg\/ddy179","article-title":"Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease","volume":"27","author":"Barny","year":"2018","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib33","doi-asserted-by":"crossref","first-page":"19691","DOI":"10.1073\/pnas.1210916109","article-title":"ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting","volume":"109","author":"Humbert","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009712_bib34","doi-asserted-by":"crossref","first-page":"28276","DOI":"10.1074\/jbc.M111.237560","article-title":"Accumulation of the Raf-1 kinase inhibitory protein (Rkip) is associated with Cep290-mediated photoreceptor degeneration in ciliopathies","volume":"286","author":"Murga-Zamalloa","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009712_bib35","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/0005-2736(82)90558-2","article-title":"Use of a density modification technique for isolation of the plasma membrane of rod outer segments","volume":"687","author":"Kamps","year":"1982","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.RA119.009712_bib36","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1083\/jcb.105.6.2589","article-title":"Differences in the protein composition of bovine retinal rod outer segment disk and plasma membranes isolated by a ricin-gold-dextran density perturbation method","volume":"105","author":"Molday","year":"1987","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib37","first-page":"50","article-title":"Peripherin. A rim-specific membrane protein of rod outer segment discs","volume":"28","author":"Molday","year":"1987","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib38","first-page":"352","article-title":"Molecular cloning, membrane topology, and localization of bovine rom-1 in rod and cone photoreceptor cells","volume":"37","author":"Moritz","year":"1996","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib39","doi-asserted-by":"crossref","first-page":"10303","DOI":"10.1074\/jbc.272.15.10303","article-title":"The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily","volume":"272","author":"Illing","year":"1997","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009712_bib40","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1242\/jcs.109.7.1803","article-title":"Distribution of guanylate cyclase within photoreceptor outer segments","volume":"109","author":"Hallett","year":"1996","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA119.009712_bib41","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1074\/mcp.M700571-MCP200","article-title":"Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusion","volume":"7","author":"Kwok","year":"2008","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/jbc.RA119.009712_bib42","doi-asserted-by":"crossref","first-page":"32670","DOI":"10.1074\/jbc.M109.047415","article-title":"Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes","volume":"284","author":"Coleman","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009712_bib43","doi-asserted-by":"crossref","first-page":"6996","DOI":"10.1016\/S0021-9258(18)83530-X","article-title":"The cGMP-gated channel of bovine rod photoreceptors is localized exclusively in the plasma membrane","volume":"264","author":"Cook","year":"1989","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009712_bib44","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1042\/BC20110034","article-title":"Intraflagellar transport proteins in ciliogenesis of photoreceptor cells","volume":"103","author":"Sedmak","year":"2011","journal-title":"Biol. Cell"},{"key":"10.1074\/jbc.RA119.009712_bib45","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1242\/jcs.039982","article-title":"Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments","volume":"122","author":"Mazelova","year":"2009","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.RA119.009712_bib46","doi-asserted-by":"crossref","first-page":"E4400","DOI":"10.1073\/pnas.1510111112","article-title":"Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome","volume":"112","author":"Datta","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009712_bib47","doi-asserted-by":"crossref","first-page":"e1007057","DOI":"10.1371\/journal.pgen.1007057","article-title":"BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment","volume":"13","author":"Hsu","year":"2017","journal-title":"PLoS Genet"},{"key":"10.1074\/jbc.RA119.009712_bib48","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/hmg\/ddx399","article-title":"Bardet-Biedl syndrome-8 (BBS8) protein is crucial for the development of outer segments in photoreceptor neurons","volume":"27","author":"Dilan","year":"2018","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib49","first-page":"2767","article-title":"Hyaluronan and the functional organization of the interphotoreceptor matrix","volume":"40","author":"Hollyfield","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib50","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.1074\/jbc.275.10.6945","article-title":"SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes","volume":"275","author":"Acharya","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009712_bib51","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ajhg.2010.07.004","article-title":"Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa","volume":"87","author":"Bandah-Rozenfeld","year":"2010","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib52","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1167\/iovs.14-14129","article-title":"IMPG2-associated retinitis pigmentosa displays relatively early macular involvement","volume":"55","author":"van Huet","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib53","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1016\/j.ophtha.2014.06.028","article-title":"Frequency and clinical pattern of vitelliform macular dystrophy caused by mutations of interphotoreceptor matrix IMPG1 and IMPG2 genes","volume":"121","author":"Meunier","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1074\/jbc.RA119.009712_bib54","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1113\/jphysiol.2002.017640","article-title":"Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors","volume":"542","author":"Demontis","year":"2002","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.RA119.009712_bib55","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00018-014-1705-1","article-title":"A di-arginine ER retention signal regulates trafficking of HCN1 channels from the early secretory pathway to the plasma membrane","volume":"72","author":"Pan","year":"2015","journal-title":"Cell. Mol. Life Sci"},{"key":"10.1074\/jbc.RA119.009712_bib56","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/MNH.0b013e3283036cbf","article-title":"Functional roles of Na,K-ATPase subunits","volume":"17","author":"Geering","year":"2008","journal-title":"Curr. Opin. Nephrol. Hypertens"},{"key":"10.1074\/jbc.RA119.009712_bib57","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1093\/hmg\/ddr022","article-title":"Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy","volume":"20","author":"Cideciyan","year":"2011","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.RA119.009712_bib58","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.cell.2007.03.053","article-title":"A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis","volume":"129","author":"Nachury","year":"2007","journal-title":"Cell"},{"key":"10.1074\/jbc.RA119.009712_bib59","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.devcel.2008.11.001","article-title":"A BBSome subunit links ciliogenesis, microtubule stability, and acetylation","volume":"15","author":"Loktev","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA119.009712_bib60","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1101\/gad.1194004","article-title":"Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport","volume":"18","author":"Blacque","year":"2004","journal-title":"Genes Dev"},{"key":"10.1074\/jbc.RA119.009712_bib61","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1083\/jcb.200909183","article-title":"The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella","volume":"187","author":"Lechtreck","year":"2009","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib62","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.cell.2010.05.015","article-title":"The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia","volume":"141","author":"Jin","year":"2010","journal-title":"Cell"},{"key":"10.1074\/jbc.RA119.009712_bib63","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.devcel.2014.09.004","article-title":"The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6\/BBS3","volume":"31","author":"Liew","year":"2014","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA119.009712_bib64","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.devcel.2014.09.011","article-title":"IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment","volume":"31","author":"Eguether","year":"2014","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA119.009712_bib65","doi-asserted-by":"crossref","first-page":"5813","DOI":"10.1038\/ncomms6813","article-title":"Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia","volume":"5","author":"Williams","year":"2014","journal-title":"Nat. Commun"},{"key":"10.1074\/jbc.RA119.009712_bib66","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1083\/jcb.201709041","article-title":"BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone","volume":"217","author":"Ye","year":"2018","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.RA119.009712_bib67","doi-asserted-by":"crossref","first-page":"E934","DOI":"10.1073\/pnas.1713226115","article-title":"The Bardet-Biedl syndrome protein complex is an adapter expanding the cargo range of intraflagellar transport trains for ciliary export","volume":"115","author":"Liu","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009712_bib68","doi-asserted-by":"crossref","first-page":"e1002358","DOI":"10.1371\/journal.pgen.1002358","article-title":"A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and smoothened","volume":"7","author":"Seo","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1074\/jbc.RA119.009712_bib69","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.1007\/s00018-013-1403-4","article-title":"Light-dependent phosphorylation of Bardet-Biedl syndrome 5 in photoreceptor cells modulates its interaction with arrestin1","volume":"70","author":"Smith","year":"2013","journal-title":"Cell. Mol. Life Sci"},{"key":"10.1074\/jbc.RA119.009712_bib70","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/bs.pmbts.2015.02.007","article-title":"Rhodopsin trafficking and mistrafficking: signals, molecular components, and mechanisms","volume":"132","author":"Nemet","year":"2015","journal-title":"Prog. Mol. Biol. Transl. Sci"},{"key":"10.1074\/jbc.RA119.009712_bib71","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.cell.2011.04.019","article-title":"Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways","volume":"145","author":"Sang","year":"2011","journal-title":"Cell"},{"key":"10.1074\/jbc.RA119.009712_bib72","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1242\/dev.02732","article-title":"Intraflagellar transport is essential for endochondral bone formation","volume":"134","author":"Haycraft","year":"2007","journal-title":"Development"},{"key":"10.1074\/jbc.RA119.009712_bib73","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1101\/gad.8.12.1434","article-title":"Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate","volume":"8","author":"Turner","year":"1994","journal-title":"Genes Dev"},{"key":"10.1074\/jbc.RA119.009712_bib74","doi-asserted-by":"crossref","first-page":"969","DOI":"10.3109\/02713688409167215","article-title":"Application of acrylamide as an embedding medium in studies of lectin and antibody binding in the vertebrate retina","volume":"3","author":"Johnson","year":"1984","journal-title":"Curr. Eye Res"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820308267?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820308267?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.RA119.009712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T23:14:53Z","timestamp":1641251693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820308267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":74,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S0021925820308267"],"URL":"https:\/\/doi.org\/10.1074\/jbc.ra119.009712","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/660738","asserted-by":"object"}]},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.RA119.009712","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Datta et al.","name":"copyright","label":"Copyright"}]}}