{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:05:12Z","timestamp":1779163512343,"version":"3.51.4"},"reference-count":58,"publisher":"Elsevier BV","issue":"39","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T00:00:00Z","timestamp":1599177600000},"content-version":"vor","delay-in-days":369,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD090083"],"award-info":[{"award-number":["R01HD090083"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD090007"],"award-info":[{"award-number":["R01HD090007"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1074\/jbc.ra119.009972","type":"journal-article","created":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T19:44:05Z","timestamp":1565379845000},"page":"14394-14405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Acyl-CoA synthetase 6 enriches seminiferous tubules with the \u03c9-3 fatty acid docosahexaenoic acid and is required for male fertility in the mouse"],"prefix":"10.1016","volume":"294","author":[{"given":"Benjamin J.","family":"Hale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina F.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sora Q.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria D.","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelley N.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9494-4245","authenticated-orcid":false,"given":"J. Thomas","family":"Brenna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian P.","family":"Hermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher B.","family":"Geyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.RA119.009972_bib1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0305-0491(76)90264-9","article-title":"The long chain metabolites of linoleic avid linolenic acids in liver and brain in herbivores and carnivores","volume":"54","author":"Crawford","year":"1976","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1074\/jbc.RA119.009972_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.plefa.2012.08.005","article-title":"A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution","volume":"88","author":"Crawford","year":"2013","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1074\/jbc.RA119.009972_bib3","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1194\/jlr.M001180","article-title":"Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice","volume":"51","author":"Roqueta-Rivera","year":"2010","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.biopha.2006.07.080","article-title":"Evolutionary aspects of diet, the omega-6\/omega-3 ratio and genetic variation: nutritional implications for chronic diseases","volume":"60","author":"Simopoulos","year":"2006","journal-title":"Biomed. Pharmacother"},{"key":"10.1074\/jbc.RA119.009972_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000448262","article-title":"Docosahexaenoic Acid","volume":"69","author":"Calder","year":"2016","journal-title":"Ann. Nutr. Metab"},{"key":"10.1074\/jbc.RA119.009972_bib6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1475-2891-13-31","article-title":"Adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003\u20132008","volume":"13","author":"Papanikolaou","year":"2014","journal-title":"Nutr. J"},{"key":"10.1074\/jbc.RA119.009972_bib7","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.theriogenology.2011.05.022","article-title":"Fish oil diets alter the phospholipid balance, fatty acid composition, and steroid hormone concentrations in testes of adult pigs","volume":"76","author":"Castellano","year":"2011","journal-title":"Theriogenology"},{"key":"10.1074\/jbc.RA119.009972_bib8","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/andr.12024","article-title":"Dietary fatty acids affect semen quality: a review","volume":"3","author":"Esmaeili","year":"2015","journal-title":"Andrology"},{"key":"10.1074\/jbc.RA119.009972_bib9","first-page":"108","article-title":"Improving sperm quality and spermatogenesis through a bioactive marine compound: an experimental study","volume":"83","author":"Lorenzetti","year":"2012","journal-title":"Acta Biomed"},{"key":"10.1074\/jbc.RA119.009972_bib10","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1017\/S0007114511001292","article-title":"Testes of obese rats are highly responsive to n-3 long-chain fatty acids","volume":"106","author":"Suh","year":"2011","journal-title":"Br. J. Nutr"},{"key":"10.1074\/jbc.RA119.009972_bib11","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/1750-3841.14017","article-title":"Replenishment of docosahexaenoic acid (DHA) in dietary n-3-deficient mice fed DHA in triglycerides or phosphatidylcholines after weaning","volume":"83","author":"Wang","year":"2018","journal-title":"J. Food Sci"},{"key":"10.1074\/jbc.RA119.009972_bib12","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1194\/jlr.M700378-JLR200","article-title":"Evidence for 26 distinct acyl-CoA synthetase genes in the human genome","volume":"48","author":"Watkins","year":"2007","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib13","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/MOL.0b013e32833884bb","article-title":"Acyl-coenzyme A synthetases in metabolic control","volume":"21","author":"Ellis","year":"2010","journal-title":"Curr. Opin. Lipidol"},{"key":"10.1074\/jbc.RA119.009972_bib14","doi-asserted-by":"crossref","first-page":"e0116587","DOI":"10.1371\/journal.pone.0116587","article-title":"Metabolic and tissue-specific regulation of acyl-CoA metabolism","volume":"10","author":"Ellis","year":"2015","journal-title":"PLoS One"},{"key":"10.1074\/jbc.RA119.009972_bib15","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1194\/jlr.S091843","article-title":"It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes","volume":"60","author":"Coleman","year":"2019","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib16","doi-asserted-by":"crossref","first-page":"12525","DOI":"10.1073\/pnas.1807958115","article-title":"Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain","volume":"115","author":"Fernandez","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib17","doi-asserted-by":"crossref","first-page":"12343","DOI":"10.1073\/pnas.1817557115","article-title":"ACSL6 is critical for maintaining brain DHA levels","volume":"115","author":"Chouinard-Watkins","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib18","doi-asserted-by":"crossref","first-page":"e1007810","DOI":"10.1371\/journal.pgen.1007810","article-title":"Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing","volume":"15","author":"Grive","year":"2019","journal-title":"PLOS Genet"},{"key":"10.1074\/jbc.RA119.009972_bib19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.devcel.2018.07.025","article-title":"A comprehensive roadmap of murine spermatogenesis defined by single-cell RNA-Seq","volume":"46","author":"Green","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.RA119.009972_bib20","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.celrep.2019.01.045","article-title":"The neonatal and adult human testis defined at the single-cell level","volume":"26","author":"Sohni","year":"2019","journal-title":"Cell Rep"},{"key":"10.1074\/jbc.RA119.009972_bib21","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1016\/j.celrep.2018.10.026","article-title":"The mammalian spermatogenesis single-cell transcriptome, from spermatogonial stem cells to spermatids","volume":"25","author":"Hermann","year":"2018","journal-title":"Cell Rep"},{"key":"10.1074\/jbc.RA119.009972_bib22","series-title":"Assessment of spermatogenesis through staging of seminiferous tubules. In Spermatogenesis: Methods and Protocols","first-page":"299","author":"Meistrich","year":"2013"},{"key":"10.1074\/jbc.RA119.009972_bib23","series-title":"Staging of mouse seminiferous tubule cross-sections. In Meiosis: Cytological Methods","first-page":"263","author":"Ahmed","year":"2009"},{"key":"10.1074\/jbc.RA119.009972_bib24","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1095\/biolreprod.113.111682","article-title":"Novel stage classification of human spermatogenesis based on acrosome development","volume":"89","author":"Muciaccia","year":"2013","journal-title":"Biol. Reprod"},{"key":"10.1074\/jbc.RA119.009972_bib25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/aja.1000960203","article-title":"Spermiogenesis of man, monkey, ram and other mammals as shown by the periodic acid\u2013Schiff technique","volume":"96","author":"Clermont","year":"1955","journal-title":"Am. J. Anat"},{"key":"10.1074\/jbc.RA119.009972_bib26","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/ar.1092230107","article-title":"Mechanism for the removal of residual cytoplasm from spermatids during mouse spermiogenesis","volume":"223","author":"Sakai","year":"1989","journal-title":"Anat. Rec"},{"key":"10.1074\/jbc.RA119.009972_bib27","doi-asserted-by":"crossref","first-page":"R43","DOI":"10.1530\/REP-15-0310","article-title":"Formation and function of the manchette and flagellum during spermatogenesis","volume":"151","author":"Lehti","year":"2016","journal-title":"Reproduction"},{"key":"10.1074\/jbc.RA119.009972_bib28","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/mrd.1040","article-title":"Spermatid manchette: plugging proteins to zero into the sperm tail","volume":"59","author":"Kierszenbaum","year":"2001","journal-title":"Mol. Reprod. Dev"},{"key":"10.1074\/jbc.RA119.009972_bib29","doi-asserted-by":"crossref","first-page":"E10132","DOI":"10.1073\/pnas.1710837114","article-title":"Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis","volume":"114","author":"Endo","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00013.2015","article-title":"Spermatogenesis: the commitment to meiosis","volume":"96","author":"Griswold","year":"2016","journal-title":"Physiol. Rev"},{"key":"10.1074\/jbc.RA119.009972_bib31","first-page":"dev170225","article-title":"Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium","volume":"146","author":"Teletin","year":"2019","journal-title":"Development"},{"key":"10.1074\/jbc.RA119.009972_bib32","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1194\/jlr.M072512","article-title":"Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids","volume":"58","author":"Klett","year":"2017","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib33","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1021\/bi047721l","article-title":"Characterization of recombinant long-chain rat acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6","volume":"44","author":"Van Horn","year":"2005","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.RA119.009972_bib34","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1095\/biolreprod.106.055095","article-title":"In the absence of the mouse DNA\/RNA-binding protein MSY2, messenger RNA instability leads to spermatogenic arrest1","volume":"76","author":"Yang","year":"2007","journal-title":"Biol. Reprod"},{"key":"10.1074\/jbc.RA119.009972_bib35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.febslet.2004.08.082","article-title":"Translin associated protein X is essential for cellular proliferation","volume":"576","author":"Yang","year":"2004","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.RA119.009972_bib36","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1073\/pnas.0408718102","article-title":"Absence of the DNA-\/RNA-binding protein MSY2 results in male and female infertility","volume":"102","author":"Yang","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib37","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1073\/pnas.0404685102","article-title":"The DNA\/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells","volume":"102","author":"Yang","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib38","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1095\/biolreprod.107.060079","article-title":"Polypyrimidine tract binding protein 2 stabilizes phosphoglycerate kinase 2 mRNA in murine male germ cells by binding to its 3\u2032UTR1","volume":"76","author":"Xu","year":"2007","journal-title":"Biol. Reprod"},{"key":"10.1074\/jbc.RA119.009972_bib39","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1095\/biolreprod.110.087114","article-title":"Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis","volume":"84","author":"Xu","year":"2011","journal-title":"Biol. Reprod"},{"key":"10.1074\/jbc.RA119.009972_bib40","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1096\/fj.201601222R","article-title":"Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms","volume":"31","author":"Serhan","year":"2017","journal-title":"FASEB J"},{"key":"10.1074\/jbc.RA119.009972_bib41","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature13479","article-title":"Pro-resolving lipid mediators are leads for resolution physiology","volume":"510","author":"Serhan","year":"2014","journal-title":"Nature"},{"key":"10.1074\/jbc.RA119.009972_bib42","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.prostaglandins.2018.09.004","article-title":"Inflammation and CB2 signaling drive novel changes in the ocular lipidome and regulate immune cell activity in the eye","volume":"139","author":"Toguri","year":"2018","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1074\/jbc.RA119.009972_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.apha.2017.04.003","article-title":"Endocannabinoid analytical methodologies: techniques that drive discoveries that drive techniques","volume":"80","author":"Piscitelli","year":"2017","journal-title":"Adv. Pharmacol"},{"key":"10.1074\/jbc.RA119.009972_bib44","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1126\/science.aad6887","article-title":"Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone","volume":"352","author":"Miller","year":"2016","journal-title":"Science"},{"key":"10.1074\/jbc.RA119.009972_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2012.01.014","article-title":"The role of endocannabinoids in gonadal function and fertility along the evolutionary axis","volume":"355","author":"Battista","year":"2012","journal-title":"Mol. Cell. Endocrinol"},{"key":"10.1074\/jbc.RA119.009972_bib46","doi-asserted-by":"crossref","first-page":"11131","DOI":"10.1073\/pnas.0812789106","article-title":"The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis","volume":"106","author":"Grimaldi","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.RA119.009972_bib47","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/molehr\/4.2.111","article-title":"The fatty acid composition of phospholipids of spermatozoa from infertile patients","volume":"4","author":"Zalata","year":"1998","journal-title":"Mol. Hum. Reprod"},{"key":"10.1074\/jbc.RA119.009972_bib48","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1194\/jlr.M011346","article-title":"ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice","volume":"52","author":"Zadravec","year":"2011","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib49","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1194\/jlr.M900039-JLR200","article-title":"Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration","volume":"50","author":"Stroud","year":"2009","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.RA119.009972_bib50","doi-asserted-by":"crossref","first-page":"12065","DOI":"10.1074\/jbc.M117.791277","article-title":"Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis","volume":"292","author":"Iizuka-Hishikawa","year":"2017","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.RA119.009972_bib51","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1530\/REP-14-0653","article-title":"Marker expression reveals heterogeneity of spermatogonia in the neonatal mouse testis","volume":"149","author":"Niedenberger","year":"2015","journal-title":"Reproduction"},{"key":"10.1074\/jbc.RA119.009972_bib52","first-page":"e50648","article-title":"Separation of spermatogenic cell types using STA-PUT velocity sedimentation","author":"Bryant","year":"2013","journal-title":"J Vis Exp"},{"key":"10.1074\/jbc.RA119.009972_bib53","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.scr.2018.01.031","article-title":"Advanced immunostaining approaches to study early male germ cell development","volume":"27","author":"Niedenberger","year":"2018","journal-title":"Stem Cell Res"},{"key":"10.1074\/jbc.RA119.009972_bib54","first-page":"36","article-title":"Image processing with ImageJ","volume":"11","author":"Abramoff","year":"2004","journal-title":"Biophotonics Int"},{"key":"10.1074\/jbc.RA119.009972_bib55","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.gene.2008.06.031","article-title":"Identification and characterization of Rhox13, a novel X-linked mouse homeobox gene","volume":"423","author":"Geyer","year":"2008","journal-title":"Gene"},{"key":"10.1074\/jbc.RA119.009972_bib56","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s11745-008-3186-1","article-title":"The influence of maternal early to mid-gestation nutrient restriction on long chain polyunsaturated fatty acids in fetal sheep","volume":"43","author":"Zhou","year":"2008","journal-title":"Lipids"},{"key":"10.1074\/jbc.RA119.009972_bib57","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/MCO.0b013e328363bc0a","article-title":"Fatty acid analysis by high resolution gas chromatography and mass spectrometry for clinical and experimental applications","volume":"16","author":"Brenna","year":"2013","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1074\/jbc.RA119.009972_bib58","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/y59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can J. Biochem. Physiol"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820349978?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820349978?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.RA119.009972","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T01:03:00Z","timestamp":1639702980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820349978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":58,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S0021925820349978"],"URL":"https:\/\/doi.org\/10.1074\/jbc.ra119.009972","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acyl-CoA synthetase 6 enriches seminiferous tubules with the \u03c9-3 fatty acid docosahexaenoic acid and is required for male fertility in the mouse","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.RA119.009972","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Hale et al.","name":"copyright","label":"Copyright"}]}}