{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:44:28Z","timestamp":1791211468601,"version":"4.1.0"},"reference-count":69,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":3219,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular & Cellular Proteomics"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1074\/mcp.m111.008094","type":"journal-article","created":{"date-parts":[[2011,8,10]],"date-time":"2011-08-10T00:45:50Z","timestamp":1312937150000},"page":"M111.008094","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Proteomic Profiling of Adipose Tissue from Zmpste24\u2212\/\u2212 Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing"],"prefix":"10.1016","volume":"10","author":[{"given":"Juan R.","family":"Peinado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro M.","family":"Quir\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina R.","family":"Pulido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Mari\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L.","family":"Mart\u00ednez-Chantar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"V\u00e1zquez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M.P.","family":"Freije","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"L\u00f3pez-Ot\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda M.","family":"Malag\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M111.008094_bib1","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1210\/jc.2004-0395","article-title":"Adipose tissue as an endocrine organ","volume":"89","author":"Kershaw","year":"2004","journal-title":"J Clin Endocrinol. Metab"},{"key":"10.1074\/mcp.M111.008094_bib2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nm0106-41","article-title":"Stressed out about obesity and insulin resistance","volume":"12","author":"de Luca","year":"2006","journal-title":"Nat. Med"},{"key":"10.1074\/mcp.M111.008094_bib3","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1146\/annurev.pathol.2.010506.091859","article-title":"Endocrine functions of adipose tissue","volume":"2","author":"Waki","year":"2007","journal-title":"Annu. Rev. Pathol"},{"key":"10.1074\/mcp.M111.008094_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-59745-245-8_1","article-title":"Overview of adipose tissue and its role in obesity and metabolic disorders","volume":"456","author":"Fr\u00fchbeck","year":"2008","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/mcp.M111.008094_bib5","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1677\/JOE-10-0272","article-title":"Lipodystrophy: Metabolic insights from a rare disorder","volume":"207","author":"Huang-Doran","year":"2010","journal-title":"J. Endocrinol"},{"key":"10.1074\/mcp.M111.008094_bib6","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1586\/14789450.5.6.827","article-title":"Adipose proteome analysis: focus on mediators of insulin resistance","volume":"5","author":"Chen","year":"2008","journal-title":"Expert Rev. Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib7","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1586\/epr.09.53","article-title":"Tackling the human adipose tissue proteome to gain insight into obesity and related pathologies","volume":"6","author":"Peral","year":"2009","journal-title":"Expert Rev. Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib8","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1021\/pr800942k","article-title":"Differential proteomics of omental and subcutaneous adipose tissue reflects their unalike biochemical and metabolic properties","volume":"8","author":"P\u00e9rez-P\u00e9rez","year":"2009","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib9","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1002\/pmic.201000350","article-title":"The stromal-vascular fraction of adipose tissue contributes to major differences between subcutaneous and visceral fat depots","volume":"10","author":"Peinado","year":"2010","journal-title":"Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib10","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1074\/mcp.M400198-MCP200","article-title":"Proteomic analysis of primary cultures of human adipose-derived stem cells: modulation by Adipogenesis","volume":"4","author":"DeLany","year":"2005","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/pmic.200800035","article-title":"Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature","volume":"9","author":"Roche","year":"2009","journal-title":"Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib12","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1021\/pr100887r","article-title":"Proteome of human subcutaneous adipose tissue stromal vascular fraction cells versus mature adipocytes based on DIGE","volume":"10","author":"Kheterpal","year":"2011","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib13","doi-asserted-by":"crossref","first-page":"5228","DOI":"10.1021\/pr100521c","article-title":"Temporal profiling of the secretome during adipogenesis in humans","volume":"9","author":"Zhong","year":"2010","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib14","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.jprot.2011.03.010","article-title":"Secretome analysis of rat adipose tissues shows location-specific roles for each depot type","volume":"74","author":"Roca-Rivada","year":"2011","journal-title":"J. Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib15","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.2337\/db08-0604","article-title":"Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals","volume":"57","author":"Boden","year":"2008","journal-title":"Diabetes"},{"key":"10.1074\/mcp.M111.008094_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006884","article-title":"Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway","volume":"4","author":"Jiang","year":"2009","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M111.008094_bib17","doi-asserted-by":"crossref","first-page":"3244","DOI":"10.1002\/pmic.200800761","article-title":"Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet","volume":"9","author":"de Roos","year":"2009","journal-title":"Proteomics"},{"key":"10.1074\/mcp.M111.008094_bib18","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1111\/j.1474-9726.2010.00613.x","article-title":"Modulation of white adipose tissue proteome by aging and calorie restriction","volume":"9","author":"Valle","year":"2010","journal-title":"Aging Cell"},{"key":"10.1074\/mcp.M111.008094_bib19","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1021\/pr901175w","article-title":"Proteomic analysis for antiobesity potential of capsaicin on white adipose tissue in rats fed with a high fat diet","volume":"9","author":"Joo","year":"2010","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib20","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.tem.2010.06.006","article-title":"Central players in inherited lipodystrophies","volume":"21","author":"Jeninga","year":"2010","journal-title":"Trends Endocrinol. Metab"},{"key":"10.1074\/mcp.M111.008094_bib21","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1056\/NEJMra025261","article-title":"Acquired and inherited lipodystrophies","volume":"350","author":"Garg","year":"2004","journal-title":"N. Engl. J. Med"},{"key":"10.1074\/mcp.M111.008094_bib22","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.2174\/138161210793563455","article-title":"Targets of Metabolic Toxicity of HIV Antiretroviral Drugs: The Multiple Roads to Lipodystrophy and Metabolic Syndrome","volume":"16","author":"Domingo","year":"2010","journal-title":"Curr. Pharm. Des"},{"key":"10.1074\/mcp.M111.008094_bib23","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1172\/JCI37679","article-title":"Laminopathies and the long strange trip from basic cell biology to therapy","volume":"119","author":"Worman","year":"2009","journal-title":"J. Clin. Invest"},{"key":"10.1074\/mcp.M111.008094_bib24","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1101\/gad.1652708","article-title":"Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin","volume":"22","author":"Dechat","year":"2008","journal-title":"Genes Dev"},{"key":"10.1074\/mcp.M111.008094_bib25","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1515\/BC.2009.080","article-title":"ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disorders","volume":"390","author":"Barrowman","year":"2009","journal-title":"Biol. Chem"},{"key":"10.1074\/mcp.M111.008094_bib26","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/ng871","article-title":"Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice","volume":"31","author":"Pendas","year":"2002","journal-title":"Nat. Genet"},{"key":"10.1074\/mcp.M111.008094_bib27","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1093\/hmg\/ddn120","article-title":"Premature aging in mice activates a systemic metabolic response involving autophagy induction","volume":"17","author":"Mari\u00f1o","year":"2008","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M111.008094_bib28","doi-asserted-by":"crossref","first-page":"16268","DOI":"10.1073\/pnas.1002696107","article-title":"Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function","volume":"107","author":"Mari\u00f1o","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M111.008094_bib29","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.18632\/aging.100262","article-title":"Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?","volume":"2","author":"Ugalde","year":"2010","journal-title":"Aging"},{"key":"10.1074\/mcp.M111.008094_bib30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nmeth1019","article-title":"Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry","volume":"4","author":"Elias","year":"2007","journal-title":"Nat. Methods"},{"key":"10.1074\/mcp.M111.008094_bib31","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.trac.2008.01.008","article-title":"LC-MS-based methodology for global metabolite profiling in metabonomics\/metabolomics","volume":"27","author":"Theodoridis","year":"2008","journal-title":"Trends Analyt. Chem"},{"key":"10.1074\/mcp.M111.008094_bib32","doi-asserted-by":"crossref","first-page":"4501","DOI":"10.1021\/pr1002593","article-title":"Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease","volume":"9","author":"Barr","year":"2010","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib33","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nm1786","article-title":"Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging","volume":"14","author":"Varela","year":"2008","journal-title":"Nat. Med"},{"key":"10.1074\/mcp.M111.008094_bib34","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1007\/s00018-009-0035-1","article-title":"Structural insight into function and regulation of carnitine palmitoyltransferase","volume":"66","author":"Rufer","year":"2009","journal-title":"Cell. Mol. Life Sci"},{"key":"10.1074\/mcp.M111.008094_bib35","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1073\/pnas.0308258100","article-title":"Rapid transformation of white adipocytes into fat-oxidizing machines","volume":"101","author":"Orci","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M111.008094_bib36","doi-asserted-by":"crossref","first-page":"6650","DOI":"10.1210\/jc.2005-1024","article-title":"Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro","volume":"90","author":"Bogacka","year":"2005","journal-title":"J. Clin. Endocrinol. Metab"},{"key":"10.1074\/mcp.M111.008094_bib37","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/wsbm.41","article-title":"Phosphoproteomics","volume":"2","author":"Ozlu","year":"2010","journal-title":"Wiley Interdiscip. Rev. Syst. Biol. Med"},{"key":"10.1074\/mcp.M111.008094_bib38","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1021\/pr0603396","article-title":"A clean, more efficient method for in-solution digestion of protein mixtures without detergent or urea","volume":"5","author":"Kim","year":"2006","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M111.008094_bib39","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1126\/science.1123965","article-title":"Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase","volume":"312","author":"Haemmerle","year":"2006","journal-title":"Science"},{"key":"10.1074\/mcp.M111.008094_bib40","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1194\/jlr.M000729","article-title":"Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells","volume":"51","author":"Duncan","year":"2010","journal-title":"J. Lipid Res"},{"key":"10.1074\/mcp.M111.008094_bib41","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1373\/clinchem.2008.115352","article-title":"Fatty acid synthase: association with insulin resistance, type 2 diabetes, and cancer","volume":"55","author":"Menendez","year":"2009","journal-title":"Clin. Chem"},{"key":"10.1074\/mcp.M111.008094_bib42","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1096\/fj.02-0407rev","article-title":"Glyceroneogenesis comes of age","volume":"16","author":"Beale","year":"2002","journal-title":"FASEB J"},{"key":"10.1074\/mcp.M111.008094_bib43","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1073\/pnas.022616299","article-title":"A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice","volume":"99","author":"Olswang","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M111.008094_bib44","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1210\/en.2009-1364","article-title":"Long-term ritonavir exposure increases fatty acid and glycerol recycling in 3T3-L1 adipocytes as compensatory mechanisms for increased triacylglycerol hydrolysis","volume":"151","author":"Adler-Wailes","year":"2010","journal-title":"Endocrinology"},{"key":"10.1074\/mcp.M111.008094_bib45","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1042\/bj3270225","article-title":"Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes","volume":"327","author":"Brown","year":"1997","journal-title":"Biochem. J"},{"key":"10.1074\/mcp.M111.008094_bib46","doi-asserted-by":"crossref","first-page":"927","DOI":"10.2353\/ajpath.2009.081155","article-title":"Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations","volume":"175","author":"De Pauw","year":"2009","journal-title":"Am. J. Pathol"},{"key":"10.1074\/mcp.M111.008094_bib47","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1086\/429697","article-title":"In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA","volume":"191","author":"Mallon","year":"2005","journal-title":"J. Infect. Dis"},{"key":"10.1074\/mcp.M111.008094_bib48","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.3851\/IMP1457","article-title":"Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months","volume":"14","author":"Boothby","year":"2009","journal-title":"Antivir. Ther"},{"key":"10.1074\/mcp.M111.008094_bib49","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1086\/599986","article-title":"Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy","volume":"200","author":"Sievers","year":"2009","journal-title":"J. Infect. Dis"},{"key":"10.1074\/mcp.M111.008094_bib50","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1128\/AAC.01449-07","article-title":"Mitochondrial DNA content, an inaccurate biomarker of mitochondrial alteration in human immunodeficiency virus-related lipodystrophy","volume":"52","author":"Kim","year":"2008","journal-title":"Antimicrob. Agents Chemother"},{"key":"10.1074\/mcp.M111.008094_bib51","doi-asserted-by":"crossref","first-page":"13432","DOI":"10.1073\/pnas.0704212104","article-title":"HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells","volume":"104","author":"Coffinier","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M111.008094_bib52","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1038\/sj.cdd.4402197","article-title":"Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence","volume":"14","author":"Caron","year":"2007","journal-title":"Cell Death Differ"},{"key":"10.1074\/mcp.M111.008094_bib53","doi-asserted-by":"crossref","first-page":"6495","DOI":"10.1021\/bi900558g","article-title":"Redox potential and peroxide reactivity of human peroxiredoxin 3","volume":"48","author":"Cox","year":"2009","journal-title":"Biochemistry"},{"key":"10.1074\/mcp.M111.008094_bib54","doi-asserted-by":"crossref","first-page":"6297","DOI":"10.1074\/jbc.273.11.6297","article-title":"Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha","volume":"273","author":"Kang","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1074\/mcp.M111.008094_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018532","article-title":"Oxidative Stress Accumulates in Adipose Tissue during Aging and Inhibits Adipogenesis","volume":"6","author":"Findeisen","year":"2011","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M111.008094_bib56","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1042\/BJ20071072","article-title":"Vimentin supports mitochondrial morphology and organization","volume":"410","author":"Tang","year":"2008","journal-title":"Biochem. J"},{"key":"10.1074\/mcp.M111.008094_bib57","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1242\/jcs.109.13.3047","article-title":"Disruption of the vimentin intermediate filament system during adipose conversion of 3T3-L1 cells inhibits lipid droplet accumulation","volume":"109","author":"Lieber","year":"1996","journal-title":"J. Cell Sci"},{"key":"10.1074\/mcp.M111.008094_bib58","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0092-8674(87)90763-X","article-title":"Rearrangement of the vimentin cytoskeleton during adipose conversion: formation of an intermediate filament cage around lipid globules","volume":"49","author":"Franke","year":"1987","journal-title":"Cell"},{"key":"10.1074\/mcp.M111.008094_bib59","doi-asserted-by":"crossref","first-page":"9244","DOI":"10.1074\/jbc.M605571200","article-title":"Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis","volume":"282","author":"Kumar","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/mcp.M111.008094_bib60","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.molcel.2007.06.029","article-title":"HMGB1 is a cofactor in mammalian base excision repair","volume":"27","author":"Prasad","year":"2007","journal-title":"Mol. Cell"},{"key":"10.1074\/mcp.M111.008094_bib61","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.4161\/auto.6.8.13651","article-title":"HMGB1: A novel Beclin 1-binding protein active in autophagy","volume":"6","author":"Kang","year":"2010","journal-title":"Autophagy"},{"key":"10.1074\/mcp.M111.008094_bib62","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/978-1-4419-7002-2_6","article-title":"Autophagy and aging: lessons from progeria models","volume":"694","author":"Mari\u00f1o","year":"2010","journal-title":"Adv. Exp. Med. Biol"},{"key":"10.1074\/mcp.M111.008094_bib63","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.mce.2007.09.012","article-title":"Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP\/F-1 mice","volume":"280","author":"Lamounier-Zepter","year":"2008","journal-title":"Mol. Cell. Endocrinol"},{"key":"10.1074\/mcp.M111.008094_bib64","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.beem.2008.10.002","article-title":"The role of the endocannabinoid system in lipogenesis and fatty acid metabolism","volume":"23","author":"Vettor","year":"2009","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab"},{"key":"10.1074\/mcp.M111.008094_bib65","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s11745-010-3392-5","article-title":"Lysophosphatidylcholine containing docosahexaenoic acid at the sn-1 position is anti-inflammatory","volume":"45","author":"Huang","year":"2010","journal-title":"Lipids"},{"key":"10.1074\/mcp.M111.008094_bib66","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1476-9255-5-17","article-title":"Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties","volume":"5","author":"Cunningham","year":"2008","journal-title":"J. Inflamm"},{"key":"10.1074\/mcp.M111.008094_bib67","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.2174\/092986707782793899","article-title":"Role of lysophosphatidylcholine (LPC) in atherosclerosis","volume":"14","author":"Matsumoto","year":"2007","journal-title":"Curr. Med. Chem"},{"key":"10.1074\/mcp.M111.008094_bib68","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s11306-006-0045-z","article-title":"Applications of a new subspace clustering algorithm (COSA) in medical systems biology","volume":"3","author":"Damian","year":"2007","journal-title":"Metabolomics"},{"key":"10.1074\/mcp.M111.008094_bib69","doi-asserted-by":"crossref","first-page":"e218","DOI":"10.1371\/journal.pone.0000218","article-title":"Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects\u2013a monozygotic twin study","volume":"2","author":"Pietil\u00e4inen","year":"2007","journal-title":"PLoS One"}],"container-title":["Molecular & Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620300955?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620300955?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M111.008094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:15:04Z","timestamp":1761524104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1535947620300955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":69,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S1535947620300955"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m111.008094","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proteomic Profiling of Adipose Tissue from Zmpste24\u2212\/\u2212 Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M111.008094","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2011 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"M111.008094"}}