{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:10:31Z","timestamp":1789783831973,"version":"4.0.1"},"reference-count":71,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":2434,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular &amp; Cellular Proteomics"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1074\/mcp.m113.029280","type":"journal-article","created":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T22:03:08Z","timestamp":1385589788000},"page":"475-488","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic\/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain"],"prefix":"10.1016","volume":"13","author":[{"given":"Fabian M.","family":"Nensa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin H.D.","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schr\u00f6tter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Przyborski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mastalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergej","family":"Susdalzew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Loo\u03b2e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Helling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouzi","family":"El Magraoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Erdmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut E.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Uszkoreit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Eisenacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehong","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne Y.","family":"Gu\u00e9nette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelli","family":"R\u00f6hner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donat","family":"K\u00f6gel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Theiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Marcus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M113.029280_bib1","doi-asserted-by":"crossref","first-page":"32869","DOI":"10.1074\/jbc.272.52.32869","article-title":"The WW domain of neural protein FE65 interacts with proline-rich motifs in MENA, the mammalian homolog of Drosophila enabled","volume":"272","author":"Ermekova","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib2","doi-asserted-by":"crossref","first-page":"17284","DOI":"10.1074\/jbc.274.24.17284","article-title":"A single point mutation in a group I WW domain shifts its specificity to that of group II WW domains","volume":"274","author":"Espanel","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib3","doi-asserted-by":"crossref","first-page":"6229","DOI":"10.1128\/MCB.16.11.6229","article-title":"The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein","volume":"16","author":"Borg","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/mcp.M113.029280_bib4","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1093\/hmg\/5.10.1589","article-title":"cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein","volume":"5","author":"Bressler","year":"1996","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M113.029280_bib5","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1152\/physrev.2001.81.2.741","article-title":"Alzheimer's disease: genes, proteins, and therapy","volume":"81","author":"Selkoe","year":"2001","journal-title":"Physiol. Rev"},{"key":"10.1074\/mcp.M113.029280_bib6","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1126\/science.1058783","article-title":"A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60","volume":"293","author":"Cao","year":"2001","journal-title":"Science"},{"key":"10.1074\/mcp.M113.029280_bib7","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1471-4159.2005.03026.x","article-title":"Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load","volume":"93","author":"Santiard-Baron","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M113.029280_bib8","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.1523\/JNEUROSCI.5451-03.2004","article-title":"FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein","volume":"24","author":"Pietrzik","year":"2004","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib9","doi-asserted-by":"crossref","first-page":"28530","DOI":"10.1074\/jbc.M203372200","article-title":"The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells","volume":"277","author":"Kinoshita","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mcn.2007.02.003","article-title":"A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching","volume":"35","author":"Ikin","year":"2007","journal-title":"Mol. Cell. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib11","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1083\/jcb.153.7.1403","article-title":"The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement","volume":"153","author":"Sabo","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/mcp.M113.029280_bib12","doi-asserted-by":"crossref","first-page":"5407","DOI":"10.1523\/JNEUROSCI.23-13-05407.2003","article-title":"The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo","volume":"23","author":"Sabo","year":"2003","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib13","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1074\/jbc.M507735200","article-title":"Fe65 interacts with P2X2 subunits at excitatory synapses and modulates receptor function","volume":"281","author":"Masin","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib14","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.nbd.2004.10.011","article-title":"Interaction of Tau with Fe65 links tau to APP","volume":"18","author":"Barbato","year":"2005","journal-title":"Neurobiol. Dis"},{"key":"10.1074\/mcp.M113.029280_bib15","doi-asserted-by":"crossref","first-page":"8354","DOI":"10.1523\/JNEUROSCI.21-21-08354.2001","article-title":"Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65","volume":"21","author":"Kinoshita","year":"2001","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib16","doi-asserted-by":"crossref","first-page":"24521","DOI":"10.1074\/jbc.M600728200","article-title":"FE65 interaction with the ApoE receptor ApoEr2","volume":"281","author":"Hoe","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib17","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1750-1326-7-9","article-title":"FE65 as a link between VLDLR and APP to regulate their trafficking and processing","volume":"7","author":"Dumanis","year":"2012","journal-title":"Mol. Neurodegener"},{"key":"10.1074\/mcp.M113.029280_bib18","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.mcn.2010.07.005","article-title":"Megalin interacts with APP and the intracellular adapter protein FE65 in neurons","volume":"45","author":"Alvira-Botero","year":"2010","journal-title":"Mol. Cell Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib19","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1128\/MCB.01280-06","article-title":"Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65","volume":"27","author":"Bao","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/mcp.M113.029280_bib20","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1016\/j.febslet.2011.09.028","article-title":"Phosphorylation of LRP1 regulates the interaction with Fe65","volume":"585","author":"Klug","year":"2011","journal-title":"FEBS Lett"},{"key":"10.1074\/mcp.M113.029280_bib21","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1021\/bi200508f","article-title":"Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein","volume":"50","author":"Mulvihill","year":"2011","journal-title":"Biochemistry"},{"key":"10.1074\/mcp.M113.029280_bib22","doi-asserted-by":"crossref","first-page":"6545","DOI":"10.1074\/jbc.M007340200","article-title":"The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation","volume":"276","author":"Minopoli","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib23","doi-asserted-by":"crossref","first-page":"40353","DOI":"10.1074\/jbc.M104059200","article-title":"Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid","volume":"276","author":"Ando","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib24","doi-asserted-by":"crossref","first-page":"4327","DOI":"10.1128\/MCB.02393-05","article-title":"Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration","volume":"26","author":"Chang","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/mcp.M113.029280_bib25","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1038\/embor.2008.188","article-title":"Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2","volume":"9","author":"Radzimanowski","year":"2008","journal-title":"EMBO Rep"},{"key":"10.1074\/mcp.M113.029280_bib26","doi-asserted-by":"crossref","first-page":"23113","DOI":"10.1074\/jbc.M800861200","article-title":"Crystal structure of the human Fe65-PTB1 domain","volume":"283","author":"Radzimanowski","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3233\/JAD-2009-0970","article-title":"Phosphorylation of a tyrosine in the amyloid-beta protein precursor intracellular domain inhibits Fe65 binding and signaling","volume":"16","author":"Zhou","year":"2009","journal-title":"J. Alzheimers Dis"},{"key":"10.1074\/mcp.M113.029280_bib28","doi-asserted-by":"crossref","first-page":"e15503","DOI":"10.1371\/journal.pone.0015503","article-title":"Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo","volume":"5","author":"Barbagallo","year":"2010","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M113.029280_bib29","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1093\/oxfordjournals.hmg.a018918","article-title":"The transcriptional factor LBP-1c\/CP2\/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease","volume":"9","author":"Lambert","year":"2000","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M113.029280_bib30","doi-asserted-by":"crossref","first-page":"20128","DOI":"10.1074\/jbc.273.32.20128","article-title":"The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2\/LSF\/LBP1","volume":"273","author":"Zambrano","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/sj.embor.7400309","article-title":"Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET","volume":"6","author":"Telese","year":"2005","journal-title":"EMBO Rep"},{"key":"10.1074\/mcp.M113.029280_bib32","doi-asserted-by":"crossref","first-page":"e5071","DOI":"10.1371\/journal.pone.0005071","article-title":"FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4","volume":"4","author":"Kajiwara","year":"2009","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M113.029280_bib33","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0092-8674(02)00809-7","article-title":"Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappa B and beta-amyloid precursor protein","volume":"110","author":"Baek","year":"2002","journal-title":"Cell"},{"key":"10.1074\/mcp.M113.029280_bib34","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1111\/j.1460-9568.2004.03611.x","article-title":"Mutation of the feh-1 gene, the Caenorhabditis elegans orthologue of mammalian Fe65, decreases the expression of two acetylcholinesterase genes","volume":"20","author":"Bimonte","year":"2004","journal-title":"Eur. J. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib35","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1242\/jcs.01323","article-title":"The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor","volume":"117","author":"von Rotz","year":"2004","journal-title":"J. Cell Sci"},{"key":"10.1074\/mcp.M113.029280_bib36","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1091\/mbc.e06-04-0283","article-title":"Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)","volume":"18","author":"Muller","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/mcp.M113.029280_bib37","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1074\/jbc.C600276200","article-title":"Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage","volume":"282","author":"Minopoli","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib38","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/sj.emboj.7600926","article-title":"Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development","volume":"25","author":"Guenette","year":"2006","journal-title":"EMBO J"},{"key":"10.1074\/mcp.M113.029280_bib39","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jprot.2013.04.026","article-title":"Differential proteomic analysis of abnormal intramyoplasmic aggregates in desminopathy","volume":"90","author":"Maerkens","year":"2013","journal-title":"J. Proteomics"},{"key":"10.1074\/mcp.M113.029280_bib40","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1074\/mcp.M112.023176","article-title":"A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients","volume":"12","author":"Kley","year":"2013","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.029280_bib41","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1074\/mcp.M112.019364","article-title":"The APP family members are key players in S-adenosylmethionine formation by MAT2A and modify BACE1 and PSEN1 gene expression\u2014relevance for Alzheimer's disease","volume":"11","author":"Schrotter","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.029280_bib42","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.bbapap.2012.07.017","article-title":"A ternary complex consisting of AICD, FE65, and TIP60 down-regulates Stathmin1","volume":"1834","author":"Muller","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/mcp.M113.029280_bib43","doi-asserted-by":"crossref","first-page":"5398","DOI":"10.1021\/pr200654k","article-title":"Sense and nonsense of pathway analysis software in proteomics","volume":"10","author":"Muller","year":"2011","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M113.029280_bib44","doi-asserted-by":"crossref","first-page":"573","DOI":"10.2174\/156720511796391827","article-title":"The AICD interacting protein DAB1 is up-regulated in Alzheimer frontal cortex brain samples and causes deregulation of proteins involved in gene expression changes","volume":"8","author":"Muller","year":"2011","journal-title":"Curr. Alzheimer Res"},{"key":"10.1074\/mcp.M113.029280_bib45","doi-asserted-by":"crossref","first-page":"e29560","DOI":"10.1371\/journal.pone.0029560","article-title":"Levetiracetam reverses synaptic deficits produced by overexpression of SV2A","volume":"6","author":"Nowack","year":"2011","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M113.029280_bib46","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF00381888","article-title":"Axoplasmic transport of horseradish peroxidase in single neurons of the dorsal root ganglion studied in vitro by microinjection","volume":"270","author":"Meller","year":"1992","journal-title":"Cell Tissue Res"},{"key":"10.1074\/mcp.M113.029280_bib47","doi-asserted-by":"crossref","DOI":"10.4061\/2010\/548145","article-title":"cNEUPRO: novel biomarkers for neurodegenerative diseases","author":"Spitzer","year":"2010","journal-title":"Int. J. Alzheimers Dis"},{"key":"10.1074\/mcp.M113.029280_bib48","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S1016-8478(23)13970-7","article-title":"The PPLA motif of glycogen synthase kinase 3beta is required for interaction with Fe65","volume":"26","author":"Lee","year":"2008","journal-title":"Mol. Cells"},{"key":"10.1074\/mcp.M113.029280_bib49","doi-asserted-by":"crossref","first-page":"42364","DOI":"10.1074\/jbc.M504278200","article-title":"Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment","volume":"280","author":"Sumioka","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib50","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1002\/pmic.200700919","article-title":"Deja vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins","volume":"8","author":"Petrak","year":"2008","journal-title":"Proteomics"},{"key":"10.1074\/mcp.M113.029280_bib51","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/1471-2105-9-271","article-title":"TiGER: a database for tissue-specific gene expression and regulation","volume":"9","author":"Liu","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"10.1074\/mcp.M113.029280_bib52","doi-asserted-by":"crossref","first-page":"15074","DOI":"10.1021\/bi051251t","article-title":"Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel","volume":"44","author":"Yamaguchi","year":"2005","journal-title":"Biochemistry"},{"key":"10.1074\/mcp.M113.029280_bib53","first-page":"2480","article-title":"FE65 regulates and interacts with the Bloom syndrome protein in dynamic nuclear spheres\u2014potential relevance to Alzheimer's disease","volume":"126","author":"Schroetter","year":"2013","journal-title":"J. Cell Sci"},{"key":"10.1074\/mcp.M113.029280_bib54","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/biof.142","article-title":"Endoplasmic reticulum calcium pumps and cancer","volume":"37","author":"Arbabian","year":"2011","journal-title":"Biofactors"},{"key":"10.1074\/mcp.M113.029280_bib55","doi-asserted-by":"crossref","first-page":"C640","DOI":"10.1152\/ajpcell.00407.2004","article-title":"Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle","volume":"288","author":"Perez","year":"2005","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"10.1074\/mcp.M113.029280_bib56","doi-asserted-by":"crossref","first-page":"4529","DOI":"10.1093\/nar\/26.19.4529","article-title":"Gene amplification and transcriptional upregulation of the sarco\/endoplasmic reticulum Ca2+ transport ATPase in thapsigargin-resistant hamster smooth muscle cells","volume":"26","author":"Rishi","year":"1998","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M113.029280_bib57","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1242\/jcs.048090","article-title":"Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway","volume":"122","author":"Goodger","year":"2009","journal-title":"J. Cell Sci"},{"key":"10.1074\/mcp.M113.029280_bib58","doi-asserted-by":"crossref","first-page":"18367","DOI":"10.1073\/pnas.0907652106","article-title":"Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain","volume":"106","author":"Ghosal","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M113.029280_bib59","doi-asserted-by":"crossref","first-page":"7952","DOI":"10.1074\/jbc.274.12.7952","article-title":"Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein","volume":"274","author":"Sabo","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib60","doi-asserted-by":"crossref","first-page":"33556","DOI":"10.1074\/jbc.273.50.33556","article-title":"Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein","volume":"273","author":"Trommsdorff","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M113.029280_bib61","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s11910-008-0053-7","article-title":"New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K (v) 7\/KCNQ\/M potassium channels","volume":"8","author":"Rogawski","year":"2008","journal-title":"Curr. Neurol. Neurosci. Rep"},{"key":"10.1074\/mcp.M113.029280_bib62","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1001\/archneurol.2009.15","article-title":"Epilepsy and cognitive impairments in Alzheimer disease","volume":"66","author":"Palop","year":"2009","journal-title":"Arch. Neurol"},{"key":"10.1074\/mcp.M113.029280_bib63","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3233\/JAD-2011-101005","article-title":"Region- and age-specific changes in glutamate transport in the AbetaPP23 mouse model for Alzheimer's disease","volume":"24","author":"Schallier","year":"2011","journal-title":"J. Alzheimers Dis"},{"key":"10.1074\/mcp.M113.029280_bib64","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.neurobiolaging.2011.09.021","article-title":"Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease","volume":"33","author":"Cassano","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1074\/mcp.M113.029280_bib65","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1101\/lm.1499309","article-title":"The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation","volume":"16","author":"Wang","year":"2009","journal-title":"Learn. Mem"},{"key":"10.1074\/mcp.M113.029280_bib66","doi-asserted-by":"crossref","first-page":"13089","DOI":"10.1523\/JNEUROSCI.2855-06.2006","article-title":"Genetic analysis of Mint\/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family","volume":"26","author":"Ho","year":"2006","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib67","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.tins.2008.06.005","article-title":"Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease","volume":"31","author":"Bezprozvanny","year":"2008","journal-title":"Trends Neurosci"},{"key":"10.1074\/mcp.M113.029280_bib68","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ejphar.2004.12.038","article-title":"Caffeine induced Ca2+ release and capacitative Ca2+ entry in human embryonic kidney (HEK293) cells","volume":"509","author":"Luo","year":"2005","journal-title":"Eur. J. Pharmacol"},{"key":"10.1074\/mcp.M113.029280_bib69","doi-asserted-by":"crossref","first-page":"e176","DOI":"10.1038\/cddis.2011.57","article-title":"New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc","volume":"2","author":"Corona","year":"2011","journal-title":"Cell Death Dis"},{"key":"10.1074\/mcp.M113.029280_bib70","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.1073\/pnas.072033799","article-title":"A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP","volume":"99","author":"Leissring","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M113.029280_bib71","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1083\/jcb.200706171","article-title":"SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production","volume":"181","author":"Green","year":"2008","journal-title":"J. Cell Biol."}],"container-title":["Molecular &amp; Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620346399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620346399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M113.029280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:03:00Z","timestamp":1761526980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1535947620346399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":71,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S1535947620346399"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m113.029280","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic\/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M113.029280","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}