{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:53:42Z","timestamp":1789412022374,"version":"build-2803163510"},"reference-count":63,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":2121,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular & Cellular Proteomics"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1074\/mcp.m113.037291","type":"journal-article","created":{"date-parts":[[2014,9,6]],"date-time":"2014-09-06T03:10:02Z","timestamp":1409973002000},"page":"3410-3420","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics"],"prefix":"10.1016","volume":"13","author":[{"given":"Daniel","family":"Hornburg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Drepper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk","family":"Butter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Meissner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sendtner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M113.037291_bib1","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.jocn.2009.03.005","article-title":"Frontotemporal dementia and motor neurone disease: overlapping clinic-pathological disorders","volume":"16","author":"Lillo","year":"2009","journal-title":"J. Clin. Neurosci"},{"key":"10.1074\/mcp.M113.037291_bib2","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S1474-4422(10)70195-2","article-title":"TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia","volume":"9","author":"Mackenzie","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1074\/mcp.M113.037291_bib3","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1136\/jnnp.2010.207464","article-title":"An estimate of amyotrophic lateral sclerosis heritability using twin data","volume":"81","author":"Al-Chalabi","year":"2010","journal-title":"J. Neurol. Neurosurg"},{"key":"10.1074\/mcp.M113.037291_bib4","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/364362c0","article-title":"Mutations in Cu\/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis","volume":"364","author":"Rosen","year":"1993","journal-title":"Nature"},{"key":"10.1074\/mcp.M113.037291_bib5","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/ng1001-166","article-title":"A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2","volume":"29","author":"Hadano","year":"2001","journal-title":"Nat. Genet"},{"key":"10.1074\/mcp.M113.037291_bib6","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1086\/421054","article-title":"DNA\/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)","volume":"74","author":"Chen","year":"2004","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/mcp.M113.037291_bib7","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1086\/425287","article-title":"A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis","volume":"75","author":"Nishimura","year":"2004","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/mcp.M113.037291_bib8","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","article-title":"Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis","volume":"314","author":"Neumann","year":"2006","journal-title":"Science"},{"key":"10.1074\/mcp.M113.037291_bib9","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1126\/science.1154584","article-title":"TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis","volume":"319","author":"Sreedharan","year":"2008","journal-title":"Science"},{"key":"10.1074\/mcp.M113.037291_bib10","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1126\/science.1165942","article-title":"Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6","volume":"323","author":"Vance","year":"2009","journal-title":"Science"},{"key":"10.1074\/mcp.M113.037291_bib11","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1126\/science.1166066","article-title":"Mutations in the FUS\/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis","volume":"323","author":"Kwiatkowski","year":"2009","journal-title":"Science"},{"key":"10.1074\/mcp.M113.037291_bib12","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.neuron.2010.11.036","article-title":"Exome sequencing reveals VCP mutations as a cause of familial ALS","volume":"68","author":"Johnson","year":"2010","journal-title":"Neuron"},{"key":"10.1074\/mcp.M113.037291_bib13","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nature11280","article-title":"Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis","volume":"488","author":"Wu","year":"2012","journal-title":"Nature"},{"key":"10.1074\/mcp.M113.037291_bib14","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nrn3430","article-title":"The changing scene of amyotrophic lateral sclerosis","volume":"14","author":"Robberecht","year":"2013","journal-title":"Nat. Rev. Neurosci"},{"key":"10.1074\/mcp.M113.037291_bib15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"10.1074\/mcp.M113.037291_bib16","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neuron.2011.09.011","article-title":"Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS","volume":"72","author":"DeJesus-Hernandez","year":"2011","journal-title":"Neuron"},{"key":"10.1074\/mcp.M113.037291_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00401-014-1329-4","article-title":"C9orf72 FTLD\/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration","volume":"128","author":"May","year":"2014","journal-title":"Acta Neuropathol"},{"key":"10.1074\/mcp.M113.037291_bib18","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s00401-012-1022-4","article-title":"The genetics and neuropathology of amyotrophic lateral sclerosis","volume":"124","author":"Al-Chalabi","year":"2012","journal-title":"Acta Neuropathol,"},{"key":"10.1074\/mcp.M113.037291_bib19","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nrneurol.2011.152","article-title":"Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis","volume":"7","author":"Ferraiuolo","year":"2011","journal-title":"Nat. Rev. Neurol"},{"key":"10.1074\/mcp.M113.037291_bib20","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.brainres.2012.01.044","article-title":"Spinal muscular atrophy: the role of SMN in axonal mRNA regulation","volume":"1462","author":"Fallini","year":"2012","journal-title":"Brain Res"},{"key":"10.1074\/mcp.M113.037291_bib21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.neulet.2012.04.079","article-title":"Cellular and molecular approaches to motor neuron therapy in amyotrophic lateral sclerosis and spinal muscular atrophy","volume":"527","author":"O'Connor","year":"2012","journal-title":"Neurosci. Lett"},{"key":"10.1074\/mcp.M113.037291_bib22","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1126\/science.8209258","article-title":"Motor-neuron degeneration in mice that express a human Cu,Zn superoxide-dismutase mutation","volume":"264","author":"Gurney","year":"1994","journal-title":"Science"},{"key":"10.1074\/mcp.M113.037291_bib23","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.cell.2008.04.039","article-title":"The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors","volume":"133","author":"Tsuda","year":"2008","journal-title":"Cell"},{"key":"10.1074\/mcp.M113.037291_bib24","doi-asserted-by":"crossref","first-page":"e13368","DOI":"10.1371\/journal.pone.0013368","article-title":"Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy","volume":"5","author":"Laird","year":"2010","journal-title":"PLoS One"},{"key":"10.1074\/mcp.M113.037291_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nprot.2009.193","article-title":"Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos","volume":"5","author":"Wiese","year":"2010","journal-title":"Nat. Protoc"},{"key":"10.1074\/mcp.M113.037291_bib26","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/aja.1001940306","article-title":"Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons","volume":"194","author":"Cashman","year":"1992","journal-title":"Dev. Dyn"},{"key":"10.1074\/mcp.M113.037291_bib27","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.1471-4159.2007.05053.x","article-title":"Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells","volume":"104","author":"Oh","year":"2008","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M113.037291_bib28","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/jnr.21507","article-title":"Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking","volume":"86","author":"Matusica","year":"2008","journal-title":"J. Neurosci. Res"},{"key":"10.1074\/mcp.M113.037291_bib29","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1046\/j.1471-4159.2000.0741895.x","article-title":"Development and characterisation of a glutamate-sensitive motor neurone cell line","volume":"74","author":"Eggett","year":"2000","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M113.037291_bib30","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1074\/mcp.M800258-MCP200","article-title":"Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions","volume":"8","author":"Pan","year":"2009","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib31","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1038\/msb.2011.81","article-title":"Deep proteome and transcriptome mapping of a human cancer cell line","volume":"7","author":"Nagaraj","year":"2011","journal-title":"Mol. Syst. Biol"},{"key":"10.1074\/mcp.M113.037291_bib32","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/msb.2011.82","article-title":"The quantitative proteome of a human cell line","volume":"7","author":"Beck","year":"2011","journal-title":"Mol. Syst. Biol"},{"key":"10.1074\/mcp.M113.037291_bib33","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrg3356","article-title":"Next-generation proteomics: towards an integrative view of proteome dynamics","volume":"14","author":"Altelaar","year":"2013","journal-title":"Nat. Rev. Genet"},{"key":"10.1074\/mcp.M113.037291_bib34","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.011015","article-title":"Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer","volume":"10","author":"Michalski","year":"2011","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib35","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00216-012-6203-4","article-title":"Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present","volume":"404","author":"Bantscheff","year":"2012","journal-title":"Anal. Bioanal. Chem"},{"key":"10.1074\/mcp.M113.037291_bib36","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.013722","article-title":"System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap","volume":"11","author":"Nagaraj","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib37","doi-asserted-by":"crossref","first-page":"5674","DOI":"10.1021\/pr900748n","article-title":"Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome","volume":"8","author":"Wisniewski","year":"2009","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M113.037291_bib38","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1038\/nprot.2007.261","article-title":"Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips","volume":"2","author":"Rappsilber","year":"2007","journal-title":"Nat. Protoc"},{"key":"10.1074\/mcp.M113.037291_bib39","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/nmeth1060","article-title":"Higher-energy C-trap dissociation for peptide modification analysis","volume":"4","author":"Olsen","year":"2007","journal-title":"Nat. Methods"},{"key":"10.1074\/mcp.M113.037291_bib40","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/nbt.1511","article-title":"MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification","volume":"26","author":"Cox","year":"2008","journal-title":"Nat. Biotechnol"},{"key":"10.1074\/mcp.M113.037291_bib41","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/pr101065j","article-title":"Andromeda: a peptide search engine integrated into the MaxQuant environment","volume":"10","author":"Cox","year":"2011","journal-title":"J. Proteome Res"},{"key":"10.1074\/mcp.M113.037291_bib42","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M113.031591","article-title":"MaxLFQ allows accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction","author":"Cox","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib43","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature10098","article-title":"Global quantification of mammalian gene expression control","volume":"473","author":"Schwanhausser","year":"2011","journal-title":"Nature"},{"key":"10.1074\/mcp.M113.037291_bib44","series-title":"R: A Language and Environment for Statistical Computing","author":"Team","year":"2008"},{"key":"10.1074\/mcp.M113.037291_bib45","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1083\/jcb.200911091","article-title":"Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions","volume":"189","author":"Hubner","year":"2010","journal-title":"J. Cell Biol"},{"key":"10.1074\/mcp.M113.037291_bib46","doi-asserted-by":"crossref","first-page":"5116","DOI":"10.1073\/pnas.091062498","article-title":"Significance analysis of microarrays applied to the ionizing radiation response","volume":"98","author":"Tusher","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M113.037291_bib47","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The Gene Ontology Consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. Genet"},{"key":"10.1074\/mcp.M113.037291_bib48","doi-asserted-by":"crossref","first-page":"D109","DOI":"10.1093\/nar\/gkr988","article-title":"KEGG for integration and interpretation of large-scale molecular data sets","volume":"40","author":"Kanehisa","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M113.037291_bib49","doi-asserted-by":"crossref","first-page":"bar009","DOI":"10.1093\/database\/bar009","article-title":"UniProt Knowledgebase: a hub of integrated protein data","volume":"2011","author":"Magrane","year":"2011","journal-title":"Database"},{"key":"10.1074\/mcp.M113.037291_bib50","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1038\/nn.3467","article-title":"Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity","volume":"16","author":"Mazzoni","year":"2013","journal-title":"Nat. Neurosci"},{"key":"10.1074\/mcp.M113.037291_bib51","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.014050","article-title":"Comparative proteomic analysis of eleven common cell lines reveals ubiquitous but varying expression of most proteins","volume":"11","author":"Geiger","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib52","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/msb.2012.44","article-title":"Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma","volume":"8","author":"Wisniewski","year":"2012","journal-title":"Mol. Syst. Biol"},{"key":"10.1074\/mcp.M113.037291_bib53","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.pneurobio.2009.05.004","article-title":"Axon guidance proteins: novel therapeutic targets for ALS?","volume":"88","author":"Schmidt","year":"2009","journal-title":"Prog. Neurobiol"},{"key":"10.1074\/mcp.M113.037291_bib54","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S1474-4422(11)70015-1","article-title":"Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease","volume":"10","author":"Philips","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1074\/mcp.M113.037291_bib55","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.014068","article-title":"Analysis of high accuracy, quantitative proteomics data in the MaxQB database","volume":"11","author":"Schaab","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M113.037291_bib56","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.bbadis.2006.05.002","article-title":"The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis","volume":"1762","author":"Van Den Bosch","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/mcp.M113.037291_bib57","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0006-8993(93)90304-6","article-title":"Spinal cord motoneurons express p75NGFR and p145trkB mRNA in amyotrophic lateral sclerosis","volume":"621","author":"Seeburger","year":"1993","journal-title":"Brain Res"},{"key":"10.1074\/mcp.M113.037291_bib58","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1006\/exnr.1996.0153","article-title":"Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: a comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS)","volume":"141","author":"Wu","year":"1996","journal-title":"Exp. Neurol"},{"key":"10.1074\/mcp.M113.037291_bib59","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1073\/pnas.0703842105","article-title":"Nogo receptor antagonizes p75NTR-dependent motor neuron death","volume":"105","author":"Dupuis","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M113.037291_bib60","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/nrn1726","article-title":"The yin and yang of neurotrophin action","volume":"6","author":"Lu","year":"2005","journal-title":"Nat. Rev. Neurosci"},{"key":"10.1074\/mcp.M113.037291_bib61","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1093\/hmg\/ddq230","article-title":"Neurotoxic effects of TDP-43 overexpression in C. elegans","volume":"19","author":"Ash","year":"2010","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M113.037291_bib62","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1073\/pnas.0912417107","article-title":"TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration","volume":"107","author":"Wils","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M113.037291_bib63","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/ana.22615","article-title":"Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders","volume":"70","author":"Jucker","year":"2011","journal-title":"Ann. Neurol"}],"container-title":["Molecular & Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620337671?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1535947620337671?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M113.037291","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:56:47Z","timestamp":1761526607000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1535947620337671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":63,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S1535947620337671"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m113.037291","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M113.037291","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}