{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:42:13Z","timestamp":1791999733431,"version":"4.4.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T00:00:00Z","timestamp":1600128000000},"content-version":"vor","delay-in-days":1567,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS073584"],"award-info":[{"award-number":["NS073584"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM103507"],"award-info":[{"award-number":["GM103507"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["IOS1021860"],"award-info":[{"award-number":["IOS1021860"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular & Cellular Proteomics"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1074\/mcp.m115.051920","type":"journal-article","created":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T01:26:54Z","timestamp":1459992414000},"page":"2055-2075","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Nucleolar Enrichment of Brain Proteins with Critical Roles in Human Neurodevelopment"],"prefix":"10.1016","volume":"15","author":[{"given":"Lukasz P.","family":"Slomnicki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Malinowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Kistowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Palusinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Juan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Sepp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonis","family":"Timmusk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Dadlez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Hetman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M115.051920_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00418-007-0359-6","article-title":"Nucleolus: the fascinating nuclear body","volume":"129","author":"Sirri","year":"2008","journal-title":"Histochem. Cell Biol"},{"key":"10.1074\/mcp.M115.051920_bib2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1146\/annurev.pharmtox.010909.105844","article-title":"The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer","volume":"50","author":"Drygin","year":"2010","journal-title":"Annu. Rev. Pharmacol. Toxicol"},{"key":"10.1074\/mcp.M115.051920_bib3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1039\/b919670f","article-title":"When ribosomes go bad: diseases of ribosome biogenesis","volume":"6","author":"Freed","year":"2010","journal-title":"Mol. Biosyst"},{"key":"10.1074\/mcp.M115.051920_bib4","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.bbamcr.2009.10.009","article-title":"Driving ribosome assembly","volume":"1803","author":"Kressler","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/mcp.M115.051920_bib5","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1111\/j.1471-4159.1983.tb09038.x","article-title":"Different rates of synthesis and turnover of ribosomal RNA in rat brain and liver","volume":"41","author":"Stoykova","year":"1983","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M115.051920_bib6","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.tins.2012.01.002","article-title":"Emerging roles of the neuronal nucleolus","volume":"35","author":"Hetman","year":"2012","journal-title":"Trends Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/0165-3806(85)90185-3","article-title":"Changes in nucleolar morphology and volume of the supraoptic nucleus neurons during postnatal development of the rat","volume":"354","author":"Lafarga","year":"1985","journal-title":"Brain Res"},{"key":"10.1074\/mcp.M115.051920_bib8","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/cne.903020407","article-title":"Ultrastructural and morphometric analysis of nucleolar and nuclear changes during the early growth period in hamster facial neurons","volume":"302","author":"Clark","year":"1990","journal-title":"J. Comp. Neurol"},{"key":"10.1074\/mcp.M115.051920_bib9","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.jsb.2006.12.008","article-title":"Cajal body number and nucleolar size correlate with the cell body mass in human sensory ganglia neurons","volume":"158","author":"Berciano","year":"2007","journal-title":"J. Struct. Biol"},{"key":"10.1074\/mcp.M115.051920_bib10","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1074\/jbc.M110.170134","article-title":"RNA polymerase 1-driven transcription as a mediator of BDNF-induced neurite outgrowth","volume":"286","author":"Gomes","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/mcp.M115.051920_bib11","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.molcel.2010.09.024","article-title":"The nucleolus under stress","volume":"40","author":"Boulon","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib12","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1111\/j.1471-4159.2008.05316.x","article-title":"Inhibition of nucleolar transcription as a trigger for neuronal apoptosis","volume":"105","author":"Kalita","year":"2008","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M115.051920_bib13","doi-asserted-by":"crossref","first-page":"12759","DOI":"10.1523\/JNEUROSCI.2439-08.2008","article-title":"Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice","volume":"28","author":"Parlato","year":"2008","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib14","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1083\/jcb.200812014","article-title":"In search of nonribosomal nucleolar protein function and regulation","volume":"184","author":"Pederson","year":"2009","journal-title":"J. Cell Biol"},{"key":"10.1074\/mcp.M115.051920_bib15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1083\/jcb.201105143","article-title":"The nucleolus directly regulates p53 export and degradation","volume":"194","author":"Boyd","year":"2011","journal-title":"J. Cell Biol"},{"key":"10.1074\/mcp.M115.051920_bib16","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/onc.2010.469","article-title":"Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability","volume":"30","author":"Latonen","year":"2011","journal-title":"Oncogene"},{"key":"10.1074\/mcp.M115.051920_bib17","doi-asserted-by":"crossref","first-page":"811","DOI":"10.4161\/epi.21072","article-title":"Formation of nuclear heterochromatin: the nucleolar point of view","volume":"7","author":"Guetg","year":"2012","journal-title":"Epigenetics"},{"key":"10.1074\/mcp.M115.051920_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0960-9822(01)00650-9","article-title":"Directed proteomic analysis of the human nucleolus","volume":"12","author":"Andersen","year":"2002","journal-title":"Curr. Biol"},{"key":"10.1074\/mcp.M115.051920_bib19","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1091\/mbc.e02-05-0271","article-title":"Functional proteomic analysis of human nucleolus","volume":"13","author":"Scherl","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib20","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/mas.20067","article-title":"Deciphering the human nucleolar proteome","volume":"25","author":"Coute","year":"2006","journal-title":"Mass Spectrom. Rev"},{"key":"10.1074\/mcp.M115.051920_bib21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nature03207","article-title":"Nucleolar proteome dynamics","volume":"433","author":"Andersen","year":"2005","journal-title":"Nature"},{"key":"10.1074\/mcp.M115.051920_bib22","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.molcel.2013.08.011","article-title":"The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors","volume":"51","author":"Tafforeau","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib23","doi-asserted-by":"crossref","first-page":"D181","DOI":"10.1093\/nar\/gkn804","article-title":"NOPdb: Nucleolar Proteome Database\u20132008 update","volume":"37","author":"Ahmad","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1074\/mcp.M900429-MCP200","article-title":"A quantitative proteomics analysis of subcellular proteome localization and changes induced by DNA damage","volume":"9","author":"Boisvert","year":"2010","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M115.051920_bib25","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1523\/JNEUROSCI.0590-10.2011","article-title":"Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling","volume":"31","author":"Rieker","year":"2011","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib26","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1038\/cdd.2013.66","article-title":"A neuroprotective phase precedes striatal degeneration upon nucleolar stress","volume":"20","author":"Kreiner","year":"2013","journal-title":"Cell Death Differ"},{"key":"10.1074\/mcp.M115.051920_bib27","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nmeth.1322","article-title":"Universal sample preparation method for proteome analysis","volume":"6","author":"Wisniewski","year":"2009","journal-title":"Nat. Methods"},{"key":"10.1074\/mcp.M115.051920_bib28","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1016\/j.jprot.2012.05.030","article-title":"Diffprot - software for non-parametric statistical analysis of differential proteomics data","volume":"75","author":"Malinowska","year":"2012","journal-title":"J. Proteomics"},{"key":"10.1074\/mcp.M115.051920_bib29","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nmeth785","article-title":"Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations","volume":"2","author":"Elias","year":"2005","journal-title":"Nat. Methods"},{"key":"10.1074\/mcp.M115.051920_bib30","doi-asserted-by":"crossref","DOI":"10.1145\/1656274.1656278","article-title":"The WEKA Data Mining Software: An Update","volume":"11","author":"Hall","year":"2009","journal-title":"SIGKDD Explorations"},{"key":"10.1074\/mcp.M115.051920_bib31","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1186\/1471-2105-12-317","article-title":"NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins","volume":"12","author":"Scott","year":"2011","journal-title":"BMC Bioinform"},{"key":"10.1074\/mcp.M115.051920_bib32","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1093\/hmg\/10.18.1995","article-title":"Large-scale identification of mammalian proteins localized to nuclear sub-compartments","volume":"10","author":"Sutherland","year":"2001","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M115.051920_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"Huang da","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib34","doi-asserted-by":"crossref","first-page":"W305","DOI":"10.1093\/nar\/gkp427","article-title":"ToppGene Suite for gene list enrichment analysis and candidate gene prioritization","volume":"37","author":"Chen","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib35","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1093\/hmg\/dds112","article-title":"Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects","volume":"21","author":"Sepp","year":"2012","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M115.051920_bib36","doi-asserted-by":"crossref","first-page":"11300","DOI":"10.1523\/JNEUROSCI.2270-05.2005","article-title":"Control of dendritic arborization by the phosphoinositide-3\u2032-kinase-Akt-mammalian target of rapamycin pathway","volume":"25","author":"Jaworski","year":"2005","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib37","doi-asserted-by":"crossref","first-page":"10020","DOI":"10.1523\/JNEUROSCI.2644-06.2006","article-title":"Role of megakaryoblastic acute leukemia-1 in ERK1\/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity","volume":"26","author":"Kalita","year":"2006","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib38","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.1093\/nar\/gkt159","article-title":"RNA elements directing in vivo assembly of the 7SK\/MePCE\/Larp7 transcriptional regulatory snRNP","volume":"41","author":"Muniz","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib39","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1471-4159.2005.03543.x","article-title":"NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002 by NR2B-mediated suppression of glycogen synthase kinase-3beta-induced apoptosis","volume":"96","author":"Habas","year":"2006","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M115.051920_bib40","doi-asserted-by":"crossref","first-page":"49577","DOI":"10.1074\/jbc.M111227200","article-title":"ERK1\/2 Antagonizes Glycogen Synthase Kinase-3beta -induced Apoptosis in Cortical Neurons","volume":"277","author":"Hetman","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/mcp.M115.051920_bib41","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1523\/JNEUROSCI.3574-07.2008","article-title":"Ciliary neurotrophic factor mediates dopamine D2 receptor-induced CNS neurogenesis in adult mice","volume":"28","author":"Yang","year":"2008","journal-title":"J. Neurosci"},{"key":"10.1074\/mcp.M115.051920_bib42","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1471-4159.2011.07279.x","article-title":"Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide-induced DNA damage","volume":"117","author":"Pietrzak","year":"2011","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M115.051920_bib43","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1073\/pnas.1111561108","article-title":"Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin","volume":"109","author":"Liu","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/mcp.M115.051920_bib44","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jprot.2012.09.031","article-title":"Novel nucleolar isolation method reveals rapid response of human nucleolar proteomes to serum stimulation","volume":"77","author":"Liang","year":"2012","journal-title":"J. Proteomics"},{"key":"10.1074\/mcp.M115.051920_bib45","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.neuron.2013.10.036","article-title":"The central dogma decentralized: new perspectives on RNA function and local translation in neurons","volume":"80","author":"Holt","year":"2013","journal-title":"Neuron"},{"key":"10.1074\/mcp.M115.051920_bib46","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.cell.2011.03.028","article-title":"Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning","volume":"145","author":"Kondrashov","year":"2011","journal-title":"Cell"},{"key":"10.1074\/mcp.M115.051920_bib47","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1371\/journal.pone.0000037","article-title":"Ribosomal protein gene knockdown causes developmental defects in zebrafish","volume":"1","author":"Uechi","year":"2006","journal-title":"PLoS ONE"},{"key":"10.1074\/mcp.M115.051920_bib48","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1534\/genetics.114.168211","article-title":"A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans","volume":"198","author":"Brooks","year":"2014","journal-title":"Genetics"},{"key":"10.1074\/mcp.M115.051920_bib49","doi-asserted-by":"crossref","first-page":"D218","DOI":"10.1093\/nar\/gkj004","article-title":"NOPdb: Nucleolar Proteome Database","volume":"34","author":"Leung","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib50","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.molimm.2011.09.005","article-title":"Proteomic profiling of the human T-cell nucleolus","volume":"49","author":"Jarboui","year":"2011","journal-title":"Mol. Immunol"},{"key":"10.1074\/mcp.M115.051920_bib51","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1093\/nar\/gkn061","article-title":"LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated","volume":"36","author":"Krueger","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib52","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.molcel.2008.01.003","article-title":"A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis","volume":"29","author":"He","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib53","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1093\/nar\/gkq1153","article-title":"7SK small nuclear RNA directly affects HMGA1 function in transcription regulation","volume":"39","author":"Eilebrecht","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib54","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1091\/mbc.e04-11-0992","article-title":"Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition","volume":"16","author":"Shav-Tal","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib55","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/embor.2008.72","article-title":"The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes","volume":"9","author":"Markert","year":"2008","journal-title":"EMBO Rep"},{"key":"10.1074\/mcp.M115.051920_bib56","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/nmeth.1714","article-title":"MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics","volume":"8","author":"Ting","year":"2011","journal-title":"Nat. Methods"},{"key":"10.1074\/mcp.M115.051920_bib57","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1242\/jcs.113.24.4463","article-title":"Characterisation of transcriptionally active and inactive chromatin domains in neurons","volume":"113","author":"Akhmanova","year":"2000","journal-title":"J. Cell Sci"},{"key":"10.1074\/mcp.M115.051920_bib58","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1042\/bj0980636","article-title":"The relationship between cellular nucleic acids in the developing rat cerebral cortex","volume":"98","author":"Adams","year":"1966","journal-title":"Biochem. J"},{"key":"10.1074\/mcp.M115.051920_bib59","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1111\/j.1471-4159.1967.tb09518.x","article-title":"The effects of maturation on in vitro RNA synthesis by mouse brain cells","volume":"14","author":"Johnson","year":"1967","journal-title":"J. Neurochem"},{"key":"10.1074\/mcp.M115.051920_bib60","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/bj1540529","article-title":"Nucleo-cytoplasmic relationships of high-molecular-weight ribonucleic acid, including polyadenylated species, in the developing rat brain","volume":"154","author":"Berthold","year":"1976","journal-title":"Biochem. J"},{"key":"10.1074\/mcp.M115.051920_bib61","doi-asserted-by":"crossref","first-page":"5721","DOI":"10.1074\/jbc.M115.682161","article-title":"Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree","volume":"291","author":"Slomnicki","year":"2016","journal-title":"J. Biol. Chem"},{"key":"10.1074\/mcp.M115.051920_bib62","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.bbadis.2013.11.010","article-title":"Ribosome biogenesis in skeletal development and the pathogenesis of skeletal disorders","volume":"1842","author":"Trainor","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/mcp.M115.051920_bib63","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.bbadis.2013.12.013","article-title":"Nucleolar stress in Diamond Blackfan anemia pathophysiology","volume":"1842","author":"Ellis","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/mcp.M115.051920_bib64","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0301-0082(87)90015-3","article-title":"Directions in neurogenetic gradients and patterns of anatomical connections in the telencephalon","volume":"29","author":"Bayer","year":"1987","journal-title":"Prog. Neurobiol"},{"key":"10.1074\/mcp.M115.051920_bib65","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1002\/humu.22175","article-title":"Loss of function mutation in LARP7, chaperone of 7SK ncRNA, causes a syndrome of facial dysmorphism, intellectual disability, and primordial dwarfism","volume":"33","author":"Alazami","year":"2012","journal-title":"Hum. Mutat"},{"key":"10.1074\/mcp.M115.051920_bib66","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1038\/emm.2013.32","article-title":"Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription","volume":"45","author":"Sweatt","year":"2013","journal-title":"Exp. Mol. Med"},{"key":"10.1074\/mcp.M115.051920_bib67","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.celrep.2014.03.053","article-title":"Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation","volume":"7","author":"Dai","year":"2014","journal-title":"Cell Rep"},{"key":"10.1074\/mcp.M115.051920_bib68","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.molcel.2009.07.008","article-title":"Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing","volume":"35","author":"Gagnon-Kugler","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1074\/mcp.M115.051920_bib69","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/stem.591","article-title":"Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells","volume":"29","author":"Peng","year":"2011","journal-title":"Stem Cells"},{"key":"10.1074\/mcp.M115.051920_bib70","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.immuni.2010.11.023","article-title":"Continuous expression of the transcription factor e2\u20132 maintains the cell fate of mature plasmacytoid dendritic cells","volume":"33","author":"Ghosh","year":"2010","journal-title":"Immunity"},{"key":"10.1074\/mcp.M115.051920_bib71","doi-asserted-by":"crossref","first-page":"e73169","DOI":"10.1371\/journal.pone.0073169","article-title":"Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation","volume":"8","author":"Forrest","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1074\/mcp.M115.051920_bib72","first-page":"311","article-title":"c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat","volume":"7","author":"Grandori","year":"2005","journal-title":"Cell Biol"},{"key":"10.1074\/mcp.M115.051920_bib73","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1093\/nar\/gkq1205","article-title":"c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation","volume":"39","author":"Poortinga","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/mcp.M115.051920_bib74","doi-asserted-by":"crossref","first-page":"e1003857","DOI":"10.1371\/journal.pgen.1003857","article-title":"Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome","volume":"9","author":"Xu","year":"2013","journal-title":"PLoS Genet"},{"key":"10.1074\/mcp.M115.051920_bib75","article-title":"l-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome","author":"Xu","year":"2014","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/mcp.M115.051920_bib76","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1074\/mcp.A111.015156","article-title":"Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription","volume":"11","author":"Tsai","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/mcp.M115.051920_bib77","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1038\/nature12819","article-title":"Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification","volume":"505","author":"Tessarz","year":"2014","journal-title":"Nature"}],"container-title":["Molecular & Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762033557X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762033557X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M115.051920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:51:58Z","timestamp":1761526318000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153594762033557X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":77,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S153594762033557X"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m115.051920","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nucleolar Enrichment of Brain Proteins with Critical Roles in Human Neurodevelopment","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M115.051920","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}