{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T04:17:23Z","timestamp":1782793043042,"version":"3.54.5"},"reference-count":78,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T00:00:00Z","timestamp":1601683200000},"content-version":"vor","delay-in-days":6730,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular &amp; Cellular Proteomics"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1074\/mcp.m200016-mcp200","type":"journal-article","created":{"date-parts":[[2003,4,2]],"date-time":"2003-04-02T16:49:56Z","timestamp":1049302196000},"page":"366-375","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["Alterations in the Mouse and Human Proteome Caused by Huntington's Disease"],"prefix":"10.1016","volume":"1","author":[{"given":"Claus","family":"Zabel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Chamrad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Priller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Woodman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut E.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian P.","family":"Bates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Klose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M200016-MCP200_bib1","series-title":"Huntington\u2019s Disease","author":"Harper","year":"1991"},{"key":"10.1074\/mcp.M200016-MCP200_bib2","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","article-title":"A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes","volume":"72","year":"1993","journal-title":"Cell."},{"key":"10.1074\/mcp.M200016-MCP200_bib3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/78054","article-title":"Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity","volume":"25","author":"Li","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/exnr.1998.6832","article-title":"Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways","volume":"152","author":"Velier","year":"1998","journal-title":"Exp. Neurol."},{"key":"10.1074\/mcp.M200016-MCP200_bib5","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1126\/science.1059581","article-title":"Loss of huntingtin-mediated BDNF gene transcription in Huntington\u2019s disease","volume":"293","author":"Zuccato","year":"2001","journal-title":"Science."},{"key":"10.1074\/mcp.M200016-MCP200_bib6","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0092-8674(00)81369-0","article-title":"Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice","volume":"87","author":"Mangiarini","year":"1996","journal-title":"Cell."},{"key":"10.1074\/mcp.M200016-MCP200_bib7","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.1523\/JNEUROSCI.19-08-03248.1999","article-title":"Characterization of progressive motor deficits in mice transgenic for the human Huntington\u2019s disease mutation","volume":"19","author":"Carter","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1074\/mcp.M200016-MCP200_bib8","doi-asserted-by":"crossref","first-page":"10428","DOI":"10.1523\/JNEUROSCI.19-23-10428.1999","article-title":"Selective discrimination learning impairments in mice expressing the human Huntington\u2019s disease mutation","volume":"19","author":"Lione","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1074\/mcp.M200016-MCP200_bib9","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.1523\/JNEUROSCI.20-13-05115.2000","article-title":"Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington\u2019s disease mutation","volume":"20","author":"Murphy","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1074\/mcp.M200016-MCP200_bib10","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0092-8674(00)80513-9","article-title":"Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation","volume":"90","author":"Davies","year":"1997","journal-title":"Cell."},{"key":"10.1074\/mcp.M200016-MCP200_bib11","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1073\/pnas.95.11.6480","article-title":"Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington\u2019s disease gene","volume":"95","author":"Cha","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib12","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0306-4522(00)00157-3","article-title":"Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington\u2019s disease mice","volume":"98","author":"Denovan-Wright","year":"2000","journal-title":"Neuroscience."},{"key":"10.1074\/mcp.M200016-MCP200_bib13","doi-asserted-by":"crossref","first-page":"6809","DOI":"10.1073\/pnas.120166397","article-title":"Severe deficiencies in dopamine signaling in presymptomatic Huntington\u2019s disease mice","volume":"97","author":"Bibb","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib14","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0306-4522(00)00008-7","article-title":"The pattern of neurodegeneration in Huntington\u2019s disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington\u2019s disease","volume":"97","author":"Glass","year":"2000","journal-title":"Neuroscience."},{"key":"10.1074\/mcp.M200016-MCP200_bib15","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/0306-4522(95)00595-1","article-title":"Reduction in enkephalin and substance P messenger RNA in the striatum of early grade Huntington\u2019s disease: a detailed cellular in situ hybridization study","volume":"72","author":"Augood","year":"1996","journal-title":"Neuroscience."},{"key":"10.1074\/mcp.M200016-MCP200_bib16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/ana.410400110","article-title":"Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington\u2019s disease","volume":"40","author":"Weeks","year":"1996","journal-title":"Ann. Neurol."},{"key":"10.1074\/mcp.M200016-MCP200_bib17","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1093\/hmg\/9.9.1259","article-title":"Decreased expression of striatal signaling genes in a mouse model of Huntington\u2019s disease","volume":"9","author":"Luthi-Carter","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib18","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1126\/science.277.5334.1990","article-title":"Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain","volume":"277","author":"DiFiglia","year":"1997","journal-title":"Science."},{"key":"10.1074\/mcp.M200016-MCP200_bib19","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1093\/hmg\/8.7.1227","article-title":"Ultrastructural localization and progressive formation of neuropil aggregates in Huntington\u2019s disease transgenic mice","volume":"8","author":"Li","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib20","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1083\/jcb.143.6.1457","article-title":"Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation","volume":"143","author":"Perez","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/mcp.M200016-MCP200_bib21","doi-asserted-by":"crossref","first-page":"11404","DOI":"10.1073\/pnas.96.20.11404","article-title":"Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells","volume":"96","author":"Kazantsev","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib22","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1046\/j.1365-2990.2000.00269.x","article-title":"Small heat shock proteins, the cytoskeleton, and inclusion body formation","volume":"26","author":"Head","year":"2000","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1074\/mcp.M200016-MCP200_bib23","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/502","article-title":"Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1","volume":"19","author":"Cummings","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib24","doi-asserted-by":"crossref","first-page":"6763","DOI":"10.1073\/pnas.100110097","article-title":"The Huntington\u2019s disease protein interacts with p53 and CREB-binding protein and represses transcription","volume":"97","author":"Steffan","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib25","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1126\/science.1056784","article-title":"Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity","volume":"291","author":"Nucifora","year":"2001","journal-title":"Science."},{"key":"10.1074\/mcp.M200016-MCP200_bib26","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1093\/hmg\/9.13.2009","article-title":"Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity","volume":"9","author":"Jana","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib27","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/S0002-9440(10)65409-0","article-title":"Formation of GFAP cytoplasmic inclusions in astrocytes and their disaggregation by \u03b1B-crystallin","volume":"154","author":"Koyama","year":"1999","journal-title":"Am. J. Pathol."},{"key":"10.1074\/mcp.M200016-MCP200_bib28","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0896-6273(00)80716-3","article-title":"Caspase-8 is required for cell death induced by expanded polyglutamine repeats","volume":"22","author":"Sanchez","year":"1999","journal-title":"Neuron."},{"key":"10.1074\/mcp.M200016-MCP200_bib29","doi-asserted-by":"crossref","first-page":"7841","DOI":"10.1073\/pnas.140202897","article-title":"Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils","volume":"97","author":"Muchowski","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib30","first-page":"1743","article-title":"Overexpression and abnormal modification of the stress proteins \u03b1B-crystallin and HSP27 in Alexander disease","volume":"143","author":"Head","year":"1993","journal-title":"Am. J. Pathol."},{"key":"10.1074\/mcp.M200016-MCP200_bib31","first-page":"345","article-title":"Accumulation of \u03b1B-crystallin in central nervous system glia and neurons in pathologic conditions","volume":"140","author":"Iwaki","year":"1992","journal-title":"Am. J. Pathol."},{"key":"10.1074\/mcp.M200016-MCP200_bib32","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/00005072-198511000-00003","article-title":"Neuropathological classification of Huntington\u2019s disease","volume":"44","author":"Vonsattel","year":"1985","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1074\/mcp.M200016-MCP200_bib33","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00296185","article-title":"Expression of \u03b1B-crystallin in Alzheimer\u2019s disease","volume":"87","author":"Renkawek","year":"1994","journal-title":"Acta Neuropathol."},{"key":"10.1074\/mcp.M200016-MCP200_bib34","doi-asserted-by":"crossref","first-page":"8093","DOI":"10.1073\/pnas.110078997","article-title":"Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington\u2019s disease","volume":"97","author":"Turmaine","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib35","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/ng0297-197","article-title":"Instability of highly expanded CAG repeats in mice transgenic for the Huntington\u2019s disease mutation","volume":"15","author":"Mangiarini","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib36","first-page":"67","article-title":"Fractionated extraction of total tissue proteins from mouse and human for 2-D electrophoresis","volume":"112","author":"Klose","year":"1999","journal-title":"Methods Mol. Biol."},{"key":"10.1074\/mcp.M200016-MCP200_bib37","first-page":"147","article-title":"Large-gel 2-D electrophoresis","volume":"112","author":"Klose","year":"1999","journal-title":"Methods Mol. Biol."},{"key":"10.1074\/mcp.M200016-MCP200_bib38","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/elps.11501601175","article-title":"Two-dimensional electrophoresis of proteins: an updated protocol and implications for a functional analysis of the genome","volume":"16","author":"Klose","year":"1995","journal-title":"Electrophoresis."},{"key":"10.1074\/mcp.M200016-MCP200_bib39","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1002\/elps.1150190607","article-title":"Peptide mass fingerprint sequence coverage from differently stained proteins on two-dimensional electrophoresis patterns by matrix assisted laser desorption\/ionization-mass spectrometry (MALDI-MS)","volume":"19","author":"Scheler","year":"1998","journal-title":"Electrophoresis."},{"key":"10.1074\/mcp.M200016-MCP200_bib40","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/ng861","article-title":"Genetic analysis of the mouse brain proteome","volume":"30","author":"Klose","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib41","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1002\/1522-2683(200105)22:9<1669::AID-ELPS1669>3.0.CO;2-7","article-title":"Identification of post-translationally modified proteins in proteome studies","volume":"22","author":"Sickmann","year":"2001","journal-title":"Electrophoresis."},{"key":"10.1074\/mcp.M200016-MCP200_bib42","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1002\/elps.1150170513","article-title":"Structural analysis and identification of gel-purified proteins, available in the femtomole range, using a novel computer program for peptide sequence assignment, by matrix-assisted laser desorption ionization-reflectron time-of-flight-mass spectrometry","volume":"17","author":"Gevaert","year":"1996","journal-title":"Electrophoresis."},{"key":"10.1074\/mcp.M200016-MCP200_bib43","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1021\/ac991363o","article-title":"ProFound: an expert system for protein identification using mass spectrometric peptide mapping information","volume":"72","author":"Zhang","year":"2000","journal-title":"Anal. Chem."},{"key":"10.1074\/mcp.M200016-MCP200_bib44","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/1044-0305(94)80016-2","article-title":"An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database","volume":"5","author":"Eng","year":"1994","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"10.1074\/mcp.M200016-MCP200_bib45","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/hmg\/8.5.813","article-title":"Formation of polyglutamine inclusions in non-CNS tissue","volume":"8","author":"Sathasivam","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200016-MCP200_bib46","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0378-1119(82)90158-5","article-title":"Variation in mouse major urinary protein (MUP) genes and the MUP gene products within and between inbred lines","volume":"18","author":"Clissold","year":"1982","journal-title":"Gene."},{"key":"10.1074\/mcp.M200016-MCP200_bib47","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1002\/(SICI)1522-2683(19990701)20:10<2100::AID-ELPS2100>3.0.CO;2-D","article-title":"Proteomics in human disease: cancer, heart and infectious diseases","volume":"20","author":"Jungblut","year":"1999","journal-title":"Electrophoresis."},{"key":"10.1074\/mcp.M200016-MCP200_bib48","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0167-5699(94)90137-6","article-title":"The acute phase response","volume":"15","author":"Baumann","year":"1994","journal-title":"Immunol. Today."},{"key":"10.1074\/mcp.M200016-MCP200_bib49","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1146\/annurev.bi.52.070183.003255","article-title":"Human plasma proteinase inhibitors","volume":"52","author":"Travis","year":"1983","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/mcp.M200016-MCP200_bib50","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/00001756-199202000-00020","article-title":"\u03b11-Antitrypsin and \u03b11-antichymotrypsin are in the lesions of Alzheimer\u2019s disease","volume":"3","author":"Gollin","year":"1992","journal-title":"Neuroreport."},{"key":"10.1074\/mcp.M200016-MCP200_bib51","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1111\/j.1460-9568.1997.tb01425.x","article-title":"Serpins inhibit the toxicity of amyloid peptides","volume":"9","author":"Schubert","year":"1997","journal-title":"Eur. J. Neurosci."},{"key":"10.1074\/mcp.M200016-MCP200_bib52","doi-asserted-by":"crossref","first-page":"11798","DOI":"10.1074\/jbc.M008503200","article-title":"\u03b11-Proteinase inhibitor, \u03b11-antichymotrypsin, and \u03b12-macroglobulin are the antiapoptotic factors of vascular smooth muscle cells","volume":"276","author":"Ikari","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200016-MCP200_bib53","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1161\/01.CIR.102.12.1420","article-title":"Functional protection by acute phase proteins \u03b1(1)-acid glycoprotein and \u03b1(1)-antitrypsin against ischemia\/reperfusion injury by preventing apoptosis and inflammation","volume":"102","author":"Daemen","year":"2000","journal-title":"Circulation."},{"key":"10.1074\/mcp.M200016-MCP200_bib54","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0014-4800(68)90042-7","article-title":"Experimental hepatitis induced by @@ce:small-cap@@d@@\/ce:small-cap@@-galactosamine","volume":"9","author":"Keppler","year":"1968","journal-title":"Exp. Mol. Pathol."},{"key":"10.1074\/mcp.M200016-MCP200_bib55","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/77528","article-title":"Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington\u2019s disease","volume":"6","author":"Chen","year":"2000","journal-title":"Nat. Med."},{"key":"10.1074\/mcp.M200016-MCP200_bib56","doi-asserted-by":"crossref","first-page":"5235","DOI":"10.4049\/jimmunol.163.10.5235","article-title":"Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins","volume":"163","author":"Van Molle","year":"1999","journal-title":"J. Immunol."},{"key":"10.1074\/mcp.M200016-MCP200_bib57","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0009-8981(97)00090-9","article-title":"Albumin contamination of a purified human \u03b11-antitrypsin preparation does not affect either structural conformation or the electrophoretic mobility of the inhibitor","volume":"264","author":"Finotti","year":"1997","journal-title":"Clin. Chim. Acta."},{"key":"10.1074\/mcp.M200016-MCP200_bib58","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/311175a0","article-title":"Plasma protease inhibitors in mouse and man: divergence within the reactive centre regions","volume":"311","author":"Hill","year":"1984","journal-title":"Nature."},{"key":"10.1074\/mcp.M200016-MCP200_bib59","doi-asserted-by":"crossref","first-page":"9417","DOI":"10.1073\/pnas.88.21.9417","article-title":"Multiple murine \u03b11-protease inhibitor genes show unusual evolutionary divergence","volume":"88","author":"Borriello","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib60","doi-asserted-by":"crossref","first-page":"33293","DOI":"10.1074\/jbc.R100016200","article-title":"The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - evolution, mechanism of inhibition, novel functions, and a revised nomenclature","volume":"276","author":"Silverman","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200016-MCP200_bib61","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/oxfordjournals.molbev.a025778","article-title":"Expression of the \u03b11-proteinase inhibitor gene family during evolution of the genus Mus","volume":"14","author":"Goodwin","year":"1997","journal-title":"Mol. Biol. Evol."},{"key":"10.1074\/mcp.M200016-MCP200_bib62","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1016\/S0021-9258(18)34943-3","article-title":"Mouse plasma trypsin inhibitors. Isolation and characterization of \u03b1-1-antitrypsin and contrapsin, a novel trypsin inhibitor","volume":"257","author":"Takahara","year":"1982","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200016-MCP200_bib63","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/abbi.1997.0317","article-title":"Differential effects of heparin and glucose on structural conformation of human \u03b11 antitrypsin: evidence for a heparin-induced cleaved form of the inhibitor","volume":"347","author":"Finotti","year":"1997","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/mcp.M200016-MCP200_bib64","doi-asserted-by":"crossref","first-page":"10449","DOI":"10.1073\/pnas.89.21.10449","article-title":"\u03b1-crystallin can function as a molecular chaperone","volume":"89","author":"Horwitz","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib65","doi-asserted-by":"crossref","first-page":"3652","DOI":"10.1073\/pnas.88.9.3652","article-title":"\u03b1B-crystallin is a small heat shock protein","volume":"88","author":"Klemenz","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/mcp.M200016-MCP200_bib66","first-page":"1083","article-title":"Expression of the murine \u03b1B-crystallin gene is not restricted to the lens","volume":"9","author":"Dubin","year":"1989","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/mcp.M200016-MCP200_bib67","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0165-5728(99)00260-X","article-title":"Differential expression of stress proteins in human adult astrocytes in response to cytokines","volume":"106","author":"Bajramovic","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1074\/mcp.M200016-MCP200_bib68","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1002\/ijc.2910550511","article-title":"Expression of \u03b1B-crystallin in human brain tumors","volume":"55","author":"Aoyama","year":"1993","journal-title":"Int. J. Cancer."},{"key":"10.1074\/mcp.M200016-MCP200_bib69","doi-asserted-by":"crossref","first-page":"48417","DOI":"10.1074\/jbc.M104140200","article-title":"Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation","volume":"276","author":"Zhou","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200016-MCP200_bib70","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0167-4838(00)00149-7","article-title":"Major urinary proteins, \u03b1(2U)-globulins and aphrodisin","volume":"1482","author":"Cavaggioni","year":"2000","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1074\/mcp.M200016-MCP200_bib71","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3181\/00379727-48-13332","volume":"48","author":"Wicks","year":"1941","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1074\/mcp.M200016-MCP200_bib72","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/BF01923448","article-title":"Pheromone binding proteins of the mouse,","volume":"48","author":"Bacchini","year":"1992","journal-title":"Mus musculus. Experientia."},{"key":"10.1074\/mcp.M200016-MCP200_bib73","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1007\/PL00000880","article-title":"The vomeronasal system","volume":"58","author":"Brennan","year":"2001","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1074\/mcp.M200016-MCP200_bib74","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1006\/anbe.1997.0650","article-title":"Proteins in urine scent marks of male house mice extend the longevity of olfactory signals","volume":"55","author":"Hurst","year":"1998","journal-title":"Anim. Behav."},{"key":"10.1074\/mcp.M200016-MCP200_bib75","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1023\/A:1005578911652","article-title":"Stimulation of estrus in female mice by male urinary proteins","volume":"26","author":"Marchlewska-Koj","year":"2000","journal-title":"J. Chem. Ecol."},{"key":"10.1074\/mcp.M200016-MCP200_bib76","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/414631a","article-title":"Individual recognition in mice mediated by major urinary proteins","volume":"414","author":"Hurst","year":"2001","journal-title":"Nature."},{"key":"10.1074\/mcp.M200016-MCP200_bib77","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1161\/01.STR.32.3.753","article-title":"Acute-phase proteins before cerebral ischemia in stroke-prone rats: identification by proteomics","volume":"32","author":"Sironi","year":"2001","journal-title":"Stroke."},{"key":"10.1074\/mcp.M200016-MCP200_bib78","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/ng0597-44","article-title":"HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain","volume":"16","author":"Kalchman","year":"1997","journal-title":"Nat. Genet."}],"container-title":["Molecular &amp; Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762034439X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762034439X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M200016-MCP200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:00:35Z","timestamp":1761526835000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153594762034439X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":78,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S153594762034439X"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m200016-mcp200","relation":{},"ISSN":["1535-9476"],"issn-type":[{"value":"1535-9476","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations in the Mouse and Human Proteome Caused by Huntington's Disease","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M200016-MCP200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2002 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}