{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:53:14Z","timestamp":1762159994621,"version":"build-2065373602"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T00:00:00Z","timestamp":1601683200000},"content-version":"vor","delay-in-days":6730,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["mcponline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular & Cellular Proteomics"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1074\/mcp.m200023-mcp200","type":"journal-article","created":{"date-parts":[[2003,4,2]],"date-time":"2003-04-02T16:49:56Z","timestamp":1049302196000},"page":"394-403","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Multidomain TIGR\/Olfactomedin Protein Family with Conserved Structural Similarity in the N-terminal Region and Conserved Motifs in the C-terminal Region"],"prefix":"10.1016","volume":"1","author":[{"given":"Michelle L.","family":"Green","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teri E.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/mcp.M200023-MCP200_bib1","first-page":"656","article-title":"Similarities and differences between the TIGR and olfactomedin proteins","volume":"42","author":"Green","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1074\/mcp.M200023-MCP200_bib2","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1093\/oxfordjournals.molbev.a025975","article-title":"Molecular evolution of olfactomedin","volume":"15","author":"Karavanich","year":"1998","journal-title":"Mol. Biol. Evol."},{"key":"10.1074\/mcp.M200023-MCP200_bib3","doi-asserted-by":"crossref","first-page":"30591","DOI":"10.1074\/jbc.272.49.30591","article-title":"Understanding enzyme superfamilies. Chemistry as the fundamental determinant in the evolution of new catalytic activities","volume":"272","author":"Babbitt","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200023-MCP200_bib4","doi-asserted-by":"crossref","first-page":"6341","DOI":"10.1074\/jbc.273.11.6341","article-title":"Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells","volume":"273","author":"Nguyen","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/mcp.M200023-MCP200_bib5","first-page":"20","article-title":"GLC1A mutations point to regions of potential functional importance on the TIGR\/MYOC protein","volume":"4","author":"Rozsa","year":"1998","journal-title":"Mol. Vis."},{"key":"10.1074\/mcp.M200023-MCP200_bib6","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1017\/S0016672300004584","article-title":"Characterization and differential expression of a human gene family of olfactomedin-related proteins","volume":"76","author":"Kulkarni","year":"2000","journal-title":"Genet. Res."},{"key":"10.1074\/mcp.M200023-MCP200_bib7","first-page":"571","article-title":"Comparative analysis of multiple protein-sequence alignment methods","volume":"11","author":"McClure","year":"1994","journal-title":"Mol. Biol. Evol."},{"key":"10.1074\/mcp.M200023-MCP200_bib8","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/bioinformatics\/15.9.729","article-title":"Shotgun: getting more from sequence similarity searches","volume":"15","author":"Pegg","year":"1999","journal-title":"Bioinformatics."},{"key":"10.1074\/mcp.M200023-MCP200_bib9","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1093\/bioinformatics\/14.10.892","article-title":"JPred: a consensus secondary structure prediction server","volume":"14","author":"Cuff","year":"1998","journal-title":"Bioinformatics."},{"key":"10.1074\/mcp.M200023-MCP200_bib10","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"ClustalW: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice","volume":"22","author":"Thompson","year":"1994","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/mcp.M200023-MCP200_bib11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0959-440X(98)80073-0","article-title":"How far divergent evolution goes in proteins","volume":"8","author":"Murzin","year":"1998","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1074\/mcp.M200023-MCP200_bib12","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/372631a0","article-title":"Protein superfamilies and domain superfolds","volume":"372","author":"Orengo","year":"1994","journal-title":"Nature."},{"key":"10.1074\/mcp.M200023-MCP200_bib13","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1006\/jmbi.1997.1287","article-title":"Do aligned sequences share the same fold?","volume":"273","author":"Abagyan","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1074\/mcp.M200023-MCP200_bib14","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1093\/hmg\/6.12.2091","article-title":"Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma","volume":"6","author":"Adam","year":"1997","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib15","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJM199804093381503","article-title":"Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)","volume":"338","author":"Alward","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1074\/mcp.M200023-MCP200_bib16","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archopht.116.6.793","article-title":"A novel mutation in the GLC1A gene causes juvenile open-angle glaucoma in 4 families from the Italian region of Puglia","volume":"116","author":"Angius","year":"1998","journal-title":"Arch. Ophthalmol."},{"key":"10.1074\/mcp.M200023-MCP200_bib17","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1101\/gr.8.4.377","article-title":"Characterization and comparison of the human and mouse GLC1A glaucoma genes","volume":"8","author":"Fingert","year":"1998","journal-title":"Genome Res."},{"key":"10.1074\/mcp.M200023-MCP200_bib18","first-page":"21","article-title":"Normal homozygotes for primary open-angle glaucoma caused by the TIGR\/GLC1A gene: Evidence for a new form of dominance in man","volume":"61","author":"Raymond","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib19","first-page":"412","article-title":"Identification of new TIGR mutations in juvenile-onset primary open angle glaucoma (JOAG) families from different populations","volume":"61","author":"Stoilova","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib20","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1126\/science.275.5300.668","article-title":"Identification of a gene that causes primary open angle glaucoma","volume":"275","author":"Stone","year":"1997","journal-title":"Science."},{"key":"10.1074\/mcp.M200023-MCP200_bib21","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1086\/301612","article-title":"Mutations in the TIGR gene in familial primary open-angle glaucoma in Japan","volume":"61","author":"Suzuki","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib22","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1136\/jmg.37.4.301","article-title":"Novel mutation in the MYOC gene in primary open angle glaucoma patients","volume":"37","author":"Vasconcellos","year":"2000","journal-title":"J. Med. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib23","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1093\/hmg\/8.12.2221","article-title":"A cellular assay distinguishes normal and mutant TIGR\/myocilin protein","volume":"8","author":"Zhou","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/mcp.M200023-MCP200_bib24","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1021\/bi00699a002","article-title":"Prediction of protein conformation","volume":"13","author":"Chou","year":"1974","journal-title":"Biochemistry."},{"key":"10.1074\/mcp.M200023-MCP200_bib25","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0076-6879(96)66034-0","article-title":"GOR method for predicting protein secondary structure from amino acid sequence","volume":"266","author":"Garnier","year":"1996","journal-title":"Methods Enzymol."}],"container-title":["Molecular & Cellular Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762034442X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153594762034442X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/mcp.M200023-MCP200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T01:00:15Z","timestamp":1761526815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153594762034442X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S153594762034442X"],"URL":"https:\/\/doi.org\/10.1074\/mcp.m200023-mcp200","relation":{},"ISSN":["1535-9476"],"issn-type":[{"type":"print","value":"1535-9476"}],"subject":[],"published":{"date-parts":[[2002,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Multidomain TIGR\/Olfactomedin Protein Family with Conserved Structural Similarity in the N-terminal Region and Conserved Motifs in the C-terminal Region","name":"articletitle","label":"Article Title"},{"value":"Molecular & Cellular Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/mcp.M200023-MCP200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2002 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}