{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T18:10:14Z","timestamp":1758737414354,"version":"3.44.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["05044179","1993-1995"],"award-info":[{"award-number":["05044179","1993-1995"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Histochemica"],"published-print":{"date-parts":[[2001]]},"DOI":"10.1078\/0065-1281-00584","type":"journal-article","created":{"date-parts":[[2005,8,18]],"date-time":"2005-08-18T08:36:58Z","timestamp":1124354218000},"page":"159-165","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Immunohistochemical study of p53, p21 and PCNA in pterygium"],"prefix":"10.1016","volume":"103","author":[{"given":"Yoshiko","family":"Ueda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suketaka","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kitaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Dake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Ohira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amel Meddeb","family":"Ouertani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsugio","family":"Tsugio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1078\/0065-1281-00584_bib1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/362849a0","article-title":"Thymocyte apoptosis induced by p53-dependent and independent pathways","volume":"362","author":"Clarke","year":"1993","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib2","first-page":"582","article-title":"Comparison of clinical features of pterygium in patients in Nagasaki and Tunisia","volume":"47","author":"Dake","year":"1996","journal-title":"Folia Ophthalmol Jpn"},{"key":"10.1078\/0065-1281-00584_bib3","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1076\/ceyr.16.12.1179.5036","article-title":"P53 expression in altered limbal basal cells of pingueculae, pterygia, and limbal tumors","volume":"16","author":"Dushku","year":"1997","journal-title":"Curr Eye Res"},{"key":"10.1078\/0065-1281-00584_bib4","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0092-8674(93)90500-P","article-title":"WAF1, a potential mediator of p53 tumor suppression","volume":"75","author":"El-Deiry","year":"1993","journal-title":"Cell"},{"key":"10.1078\/0065-1281-00584_bib5","first-page":"307","article-title":"Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents","volume":"8","author":"Fritsche","year":"1993","journal-title":"Oncogene"},{"key":"10.1078\/0065-1281-00584_bib6","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/366707a0","article-title":"Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit","volume":"366","author":"Gu","year":"1993","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/path.1711620103","article-title":"Mutant p53-the commonest genetic abnormality in human cancer?","volume":"162","author":"Harris","year":"1990","journal-title":"J Pathol"},{"key":"10.1078\/0065-1281-00584_bib8","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0092-8674(93)90499-G","article-title":"The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases","volume":"75","author":"Harper","year":"1993","journal-title":"Cell"},{"key":"10.1078\/0065-1281-00584_bib9","first-page":"203","article-title":"High levels of p53 protein in UV-irradiated normal human skin","volume":"8","author":"Hall","year":"1993","journal-title":"Oncogene"},{"key":"10.1078\/0065-1281-00584_bib10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1126\/science.1905840","article-title":"P53 mutations in human cancers","volume":"253","author":"Hollstein","year":"1991","journal-title":"Science"},{"key":"10.1078\/0065-1281-00584_bib11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/path.1711700310","article-title":"Expression of p53 protein in normal, dysplastic, and malignant gastric mucosa: an immunohistochemical study","volume":"170","author":"Joypaul","year":"1993","journal-title":"J Pathol"},{"key":"10.1078\/0065-1281-00584_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/358015a0","article-title":"Cancer. P53, guardian of the genome","volume":"358","author":"Lane","year":"1992","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib13","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/362786a0","article-title":"A death in the life of p53","volume":"362","author":"Lane","year":"1993","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib14","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/371534a0","article-title":"Differential effect by the p21 CDK inhibitor on PCNA-dependent DNAreplication and repair","volume":"371","author":"Li","year":"1994","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib15","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/362847a0","article-title":"P53 is required for radiation-induced apoptosis in mouse thymocytes","volume":"362","author":"Lowe","year":"1993","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib16","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1006\/excr.1994.1063","article-title":"Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen","volume":"211","author":"Noda","year":"1994","journal-title":"Exp Cell Res"},{"key":"10.1078\/0065-1281-00584_bib17","doi-asserted-by":"crossref","first-page":"22008","DOI":"10.1074\/jbc.270.37.22008","article-title":"Inhibition of nucleotide excision repair","volume":"270","author":"Pan","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1078\/0065-1281-00584_bib18","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1177\/39.6.1709656","article-title":"Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue section","volume":"39","author":"Shi","year":"1991","journal-title":"J Histochem Cytochem"},{"key":"10.1078\/0065-1281-00584_bib19","series-title":"An atlas and textbook (4th Ed)","first-page":"235","article-title":"Cornea. Ophthalmic pathology","author":"Spencer","year":"1996"},{"key":"10.1078\/0065-1281-00584_bib20","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/369574a0","article-title":"The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA","volume":"369","author":"Waga","year":"1994","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib21","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/366701a0","article-title":"P21 is a universal inhibitor of cyclin kinases","volume":"366","author":"Xiong","year":"1993","journal-title":"Nature"},{"key":"10.1078\/0065-1281-00584_bib22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/352345a0","article-title":"Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6","volume":"352","author":"Yonish-Rouach","year":"1991","journal-title":"Nature"}],"container-title":["Acta Histochemica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065128104700653?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065128104700653?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:53:09Z","timestamp":1758736389000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0065128104700653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001]]}},"alternative-id":["S0065128104700653"],"URL":"https:\/\/doi.org\/10.1078\/0065-1281-00584","relation":{},"ISSN":["0065-1281"],"issn-type":[{"type":"print","value":"0065-1281"}],"subject":[],"published":{"date-parts":[[2001]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunohistochemical study of p53, p21 and PCNA in pterygium","name":"articletitle","label":"Article Title"},{"value":"Acta Histochemica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1078\/0065-1281-00584","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Urban & Fischer Verlag. Published by Elsevier GmbH All rights reserved.","name":"copyright","label":"Copyright"}]}}