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Administration of increasing doses of thiocyanate raised the plasma thiocyanate concentration and reduced the thyroid iodine content and the plasma protein-bound iodine.<\/jats:p><jats:p>3. In producing these effects, the daily ingestion of 10 g cassava root containing 1\u00b76 mg cyanide was approximately equivalent to a daily intake of about 1\u20132 mg thiocyanate.<\/jats:p><jats:p>4. 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