{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:04:06Z","timestamp":1760645046832},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,7,24]],"date-time":"2007-07-24T00:00:00Z","timestamp":1185235200000},"content-version":"unspecified","delay-in-days":12622,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1973,1]]},"abstract":"<jats:p>1. Rats were given a low-protein (10 g\/kg) diet for 16 weeks and the changes occurring in their serum amino acids were studied; during this time a full picture of protein-energy malnutrition was manifested. Groups of rats were killed at intervals of 4 weeks.<\/jats:p><jats:p>2. Food intake decreased gradually from the 4th to the 8th week, then increased slightly from the 9th to the 11th week, and then decreased again.<\/jats:p><jats:p>3. The body-weight of the rats fell progressively from the 1st week on the low-protein diet, remained stationary from the 10th to the 13th week, and then decreased again during the last 4 weeks.<\/jats:p><jats:p>4. The ratio of non-essential to essential amino acid was not correlated with the severity of protein deficiency.<\/jats:p><jats:p>5. The ratios between some individual amino acids were compared with these ratios in control rats during the 4-week periods of protein deficiency. The ratio of serine+glycine to threonine was always significantly higher in the protein-deficient than in the control rats.<\/jats:p>","DOI":"10.1079\/bjn19730083","type":"journal-article","created":{"date-parts":[[2005,5,13]],"date-time":"2005-05-13T04:37:29Z","timestamp":1115959049000},"page":"113-120","source":"Crossref","is-referenced-by-count":7,"title":["Experimental protein-energy deficiency in rats. Ratio of serine+glycine to threonine as an index of deficiency"],"prefix":"10.1017","volume":"29","author":[{"given":"Sohair I.","family":"Salem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Hegazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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