{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:38:48Z","timestamp":1759541928302},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2008,3,25]],"date-time":"2008-03-25T00:00:00Z","timestamp":1206403200000},"content-version":"unspecified","delay-in-days":11712,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1976,3]]},"abstract":"<jats:p>1. The observation that thyroid C cell hyperplasia occurred in rats given the iron-deficient diet described by McCall, Newman, O'Brien, Valberg &amp; Witts (1962) prompted a closer study of the preparation and constituents of this diet..<\/jats:p><jats:p>2. It became apparent that there was a discrepancy between the amounts of fat-soluble vitamins in the dietary formulation reported and the supposed final content of the diet. A diet prepared as described by McCall<jats:italic>et al.<\/jats:italic>(1962) contains 1000 \u03bcg (40000 i.u.) ergocalciferol and 10 \u03bcg (14 500 i.u.) retinyl palmitate\/kg..<\/jats:p><jats:p>3. An experiment was designed to study the effect of Fe-deficient and Fe-supplemented, high-vitamin-D diets, and an Fe-supplemented, normal-vitamin-D diet, on thyroid C cell volume and serum calcium concentration..<\/jats:p><jats:p>4. Thyroid C cell volumes and serum Ca concentrations were significantly higher in both groups given excess vitamin D than in the group given the Fe-supplemented, normal-vitamin-D diet. It is evident therefore, that hypervitaminosis D was the cause of the morphological and biochemical changes found in rats given the McCall<jats:italic>et al.<\/jats:italic>(1962) diet.<\/jats:p>","DOI":"10.1079\/bjn19760032","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T04:07:20Z","timestamp":1126930040000},"page":"277-280","source":"Crossref","is-referenced-by-count":2,"title":["Excessive vitamin D content of a standard iron-deficient diet for rats"],"prefix":"10.1017","volume":"35","author":[{"given":"Stella M.","family":"Triggs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2008,3,25]]},"reference":[{"key":"S0007114576000986_ref007","doi-asserted-by":"publisher","DOI":"10.1007\/BF01944797"},{"key":"S0007114576000986_ref017","unstructured":"Triggs S. M. (1974). Studies on the role of dietary factors in the induction of tumours of the thyroid and parathyroid. PhD Thesis, University of Wales."},{"key":"S0007114576000986_ref016","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1152\/ajplegacy.1971.220.3.674","volume":"220","author":"Thomson","year":"1971","journal-title":"Am. J. Physiol."},{"key":"S0007114576000986_ref014","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19690012"},{"key":"S0007114576000986_ref015","doi-asserted-by":"publisher","DOI":"10.1210\/endo-68-2-292"},{"key":"S0007114576000986_ref001","first-page":"193","volume":"56","author":"Bailey-Wood","year":"1975","journal-title":"J. exp. Path."},{"key":"S0007114576000986_ref008","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/58.5.376"},{"key":"S0007114576000986_ref011","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19620031"},{"key":"S0007114576000986_ref003","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1182\/blood.V42.1.131.131","volume":"43","author":"Bedard","year":"1973","journal-title":"Blood"},{"key":"S0007114576000986_ref002","first-page":"944","volume":"65","author":"Bannerman","year":"1965","journal-title":"J. Lab. clin. Med."},{"key":"S0007114576000986_ref012","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1972.tb07095.x"},{"key":"S0007114576000986_ref005","volume-title":"Elementary Statistics","author":"Croxton","year":"1959"},{"key":"S0007114576000986_ref009","volume-title":"Hypervitaminosis D. K\u00f8benhaun","author":"Guldager","year":"1936"},{"key":"S0007114576000986_ref006","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/jn\/97.4.475","volume":"97","author":"Dallman","year":"1969","journal-title":"J. Nutr."},{"key":"S0007114576000986_ref013","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1965.tb04283.x"},{"key":"S0007114576000986_ref010","doi-asserted-by":"publisher","DOI":"10.1007\/BF00525003"},{"key":"S0007114576000986_ref004","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19690074"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114576000986","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T15:51:47Z","timestamp":1586447507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114576000986\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,3]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,3]]}},"alternative-id":["S0007114576000986"],"URL":"https:\/\/doi.org\/10.1079\/bjn19760032","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,3]]}}}