{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:06:18Z","timestamp":1760954778067},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2008,12,8]],"date-time":"2008-12-08T00:00:00Z","timestamp":1228694400000},"content-version":"unspecified","delay-in-days":10875,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1979,3]]},"abstract":"<jats:p>1. Male guinea-pigs were assigned to four different groups at birth. The heaviest group of animals was severely undernourished from 21 d of age (weight gain: 1.2 g\/d <jats:italic>v.<\/jats:italic> 10 g\/d for normally-fed animals).<\/jats:p><jats:p>2. At 35, 45, 55 and 65 d of age in normally-fed animals, and at 45 and 55 d of age in undernourished animals, blood testosterone levels were determined by radioimmunoassay, epididymidal tissue examined for the presence of spermatozoa and testes sectioned for rating of spermatogenesis using light microscopy.<\/jats:p><jats:p>3. Sexual maturity in terms of potential fertility (spermatozoa in the epididymis) was reached by all normally-fed animals between 45 and 55 d of age. High birth-weight animals had a higher incidence of the most advanced stages of spermatogenesis than low birth-weight ones at the various ages studied. In the undernourished animals spermatogenesis was clearly delayed.<\/jats:p><jats:p>4. Plasma testosterone concentrations were already in the adult range at 35 d and independent of age and birth-weight. The undernourished animals, however, had very low levels. Maintenance of spermatogenesis seemed compatible with low plasma levels of testosterone.<\/jats:p><jats:p>5. It is concluded that the timing of testicular development seems to be determined by the time the animals are born and appears to be unaffected by severe undernutrition from 21 d of age.<\/jats:p>","DOI":"10.1079\/bjn19790032","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T04:07:20Z","timestamp":1126930040000},"page":"231-237","source":"Crossref","is-referenced-by-count":19,"title":["Body growth, puberty and undernutrition in the male guinea-pig"],"prefix":"10.1017","volume":"41","author":[{"given":"A. Koos","family":"Slob","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. T. M.","family":"Vreeburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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