{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:24:09Z","timestamp":1758479049009},"reference-count":6,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":9259,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1981,11]]},"abstract":"<jats:p>1. The excretion of <jats:sup>75<\/jats:sup>Se and stable Se in bile and urine was measured in four steers during 6 h after intravenous injections of <jats:sup>75<\/jats:sup>Se as either selenite or selenate containing either 5 or 5000 \u03bcg carrier Se.<\/jats:p><jats:p>2. When 5000 \u03bcg Se were given, the rate of urinary excretion and plasma clearance of <jats:sup>75<\/jats:sup>Se was similar for both salts. Approximately 23% was excreted in urine and plasma clearance was triexponential, the mean half-life (t<jats:sub>\u00bd<\/jats:sub>) of the successive components, \u03b1, \u03b2 and \u03b3, being 2\u00b73, 15\u00b72 and 465 min respectively. The amount of <jats:sup>75<\/jats:sup>Se excreted in bile was small; 1\u00b794% of the <jats:sup>75<\/jats:sup>SeO<jats:sub>3<\/jats:sub><jats:sup>2\u2212<\/jats:sup> and 0\u00b786% of the <jats:sup>75<\/jats:sup>SeO<jats:sub>4<\/jats:sub><jats:sup>2\u2212<\/jats:sup> dose.<\/jats:p><jats:p>3. When 5 \u03bcg Se were given the plasma clearance of <jats:sup>75<\/jats:sup>Se was initially biexponential but the entry of <jats:sup>75<\/jats:sup>Se-labelled protein from the liver caused an increase in plasma radioactivity after 30\u201340 min. The effect was most marked after 5 \u03bcg <jats:sup>75<\/jats:sup>SeO<jats:sub>3<\/jats:sub><jats:sup>2\u2212<\/jats:sup> when plasma <jats:sup>75<\/jats:sup>Se radioactivity returned to 60% of the activity present at 2 min. Values for t<jats:sub>\u00bd<\/jats:sub> of the two components of clearance for <jats:sup>75<\/jats:sup>SeO<jats:sub>3<\/jats:sub><jats:sup>2\u2212<\/jats:sup> and <jats:sup>75<\/jats:sup>SeO<jats:sub>4<\/jats:sub><jats:sup>2\u2212<\/jats:sup> were respectively \u03b1 2\u00b76 and 2\u00b75 min, and \u03b2 15\u00b79 and 36\u00b76 min. Similar amounts of <jats:sup>75<\/jats:sup>Se appeared in bile (0\u00b72% of the dose) after injections of either salt but much less <jats:sup>75<\/jats:sup>Se was excreted in urine after <jats:sup>75<\/jats:sup>SeO<jats:sub>3<\/jats:sub><jats:sup>2\u2212<\/jats:sup> (6%) than after <jats:sup>75<\/jats:sup>SeO<jats:sub>4<\/jats:sub><jats:sup>2\u2212<\/jats:sup> (37%).<\/jats:p><jats:p>4. At low dosage rates (5 \u03bcg) Se is more readily incorporated into tissues from SeO<jats:sub>3<\/jats:sub><jats:sup>2\u2212<\/jats:sup> than from SeO<jats:sub>4<\/jats:sub><jats:sup>2\u2212<\/jats:sup>.<\/jats:p>","DOI":"10.1079\/bjn19810057","type":"journal-article","created":{"date-parts":[[2005,5,18]],"date-time":"2005-05-18T23:51:57Z","timestamp":1116460317000},"page":"487-493","source":"Crossref","is-referenced-by-count":3,"title":["The excretion of selenium in bile and urine of steers: the influence of form and amount of Se salt"],"prefix":"10.1017","volume":"46","author":[{"given":"H. W.","family":"Symonds","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise L.","family":"Mather","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"Vagg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S0007114581001335_ref004","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0034-5288(18)32915-1","volume":"26","author":"Little","year":"1979","journal-title":"Res. vet. Sci."},{"key":"S0007114581001335_ref001","first-page":"2","volume":"21","author":"Dejneka","year":"1979","journal-title":"Polski Archwum Wet."},{"key":"S0007114581001335_ref002","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1962.sp006927"},{"key":"S0007114581001335_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0020-708X(67)90054-3"},{"key":"S0007114581001335_ref005","author":"Symonds","year":"1982","journal-title":"Res. vet. Sci."},{"key":"S0007114581001335_ref006","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19810084"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114581001335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T19:24:44Z","timestamp":1558812284000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114581001335\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,11]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1981,11]]}},"alternative-id":["S0007114581001335"],"URL":"https:\/\/doi.org\/10.1079\/bjn19810057","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,11]]}}}