{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T12:53:48Z","timestamp":1762520028929},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":9504,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1981,3]]},"abstract":"<jats:p>1. Serum levels of retinol-binding protein (RBP), total vitamin A and retinyl ester were measured in twenty-four malnourished children with corneal lesions and nine normal children.<\/jats:p><jats:p>2. Initially, the RBP and vitamin A levels were significantly lower in malnourished children than in normal children.<\/jats:p><jats:p>3. After intramuscular injection of 30000 \u03bcg of aqueous vitamin A, serum levels of total vitamin A were increased significantly at 24 h and tended to fall within 5 d of treatment in both groups.<\/jats:p><jats:p>4. Before treatment, retinyl ester accounted for less than 10% of the vitamin in circulation. After vitamin A injection, it increased to 30%, a level much lower than that reported in patients with hypervitaminosis A.<\/jats:p><jats:p>5. There was no significant difference between the two groups of children and none of them showed clinical signs of toxicity. These observations indicate that administration of massive doses of vitamin A over a short period will not produce toxic effects even in malnourished children.<\/jats:p>","DOI":"10.1079\/bjn19810098","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T04:07:20Z","timestamp":1126930040000},"page":"229-232","source":"Crossref","is-referenced-by-count":5,"title":["Effect of intramuscular vitamin A injection on plasma levels of vitamin A and retinol-binding protein in malnourished children"],"prefix":"10.1017","volume":"45","author":[{"given":"Vinodini","family":"Reddy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mohanram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S0007114581000317_ref011","first-page":"198","author":"Reddy","year":"1978","journal-title":"Proc. int. 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