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Controls received an equal volume of sucrose solution.<\/jats:p><jats:p>2. A dose of 50 mg ascorbic acid\/d resulted in a significant rise in the specific activities of both cytochromes P-450 and b<jats:sub>5<\/jats:sub>. At doses of 200 and 300 mg ascorbic acid\/d the concentration of both haemoproteins was significantly lower than the control values. These effects were mirrored by total microsomal haem concentration.<\/jats:p><jats:p>3. 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