{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:18:43Z","timestamp":1767925123477,"version":"3.49.0"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":8408,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1984,3]]},"abstract":"<jats:p>1. Groups of rainbow trout (Salmo gairdneri) (mean weight 14 g) were given diets containing 0.8, 1.3, 2, 3, 4 or 6 g tryptophan\/kg diet for 12 weeks.<\/jats:p>\n\t  <jats:p>2. By analysis of the growth results, the dietary requirement of tryptophan was found to be 2.5 g\/kg diet (equivalent to 50 mg\/kg biomass per d).<\/jats:p>\n\t  <jats:p>3. Carbon dioxide expired by trout following intraperitoneal injection of [<jats:sup>14<\/jats:sup>COOH]tryptophan contained little radioactivity when dietary tryptophan level was low but, above 2.0 g\/kg diet, it increased rapidly with increasing dietary tryptophan level. The break point in the dose-response curve did not, however, coincide with that from the growth results.<\/jats:p>\n\t  <jats:p>4. Changes in concentrations of free tryptophan in blood and liver and activity of hepatic tryptophan pyrrolase (<jats:italic>EC<\/jats:italic> 1.13.11.11) in response to changes in dietary tryptophan concentration did not provide reliable indicators for quantifying dietary requirement. Unlike the situation in mammals, blood tryptophan was not protein-bound to any appreciable extent. Tryptophan pyrrolase of trout has properties which suggest it has no apoenzyme form.<\/jats:p>\n\t  <jats:p>5. In fish given adequate levels of tryptophan injected intraperitoneally with a tracer dose of [<jats:sup>14<\/jats:sup>COOH]tryptophan, 60% of the dose was incorporated into body protein within 1 d. The turnover of the label in this protein is very slow.<\/jats:p>\n\t  <jats:p>6. Those trout given diets deficient in tryptophan suffered from severe scoliosis and lordosis as well as having increased liver and kidney levels of calcium, magnesium, sodium and potassium.<\/jats:p>","DOI":"10.1079\/bjn19840032","type":"journal-article","created":{"date-parts":[[2005,5,19]],"date-time":"2005-05-19T23:49:52Z","timestamp":1116546592000},"page":"279-287","source":"Crossref","is-referenced-by-count":81,"title":["The effects of dietary tryptophan levels on growth and metabolism of rainbow trout (<i>Salmo gairdneri<\/i>)"],"prefix":"10.1017","volume":"51","author":[{"given":"M. J.","family":"Walton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"Coloso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. B.","family":"Cowey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Adron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Knox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S0007114584000337_manual_ref-30","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/106.5.631"},{"key":"S0007114584000337_manual_ref-23","first-page":"145","volume-title":"Finfish Nutrition and Fishfeed Technology","author":"Nose","year":"1979"},{"key":"S0007114584000337_manual_ref-6","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(74)90275-9"},{"key":"S0007114584000337_manual_ref-31","doi-asserted-by":"publisher","DOI":"10.2331\/suisan.47.1035"},{"key":"S0007114584000337_manual_ref-17","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(82)90197-3"},{"key":"S0007114584000337_manual_ref-7","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(68)90226-2"},{"key":"S0007114584000337_manual_ref-27","volume-title":"Principles and Procedures of Statistics","author":"Steel","year":"1980"},{"key":"S0007114584000337_manual_ref-5","volume-title":"Amino Acid Metabolism","author":"Bender","year":"1978"},{"key":"S0007114584000337_manual_ref-12","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(73)90318-0"},{"key":"S0007114584000337_manual_ref-32","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/102.12.1655"},{"key":"S0007114584000337_manual_ref-28","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/112.8.1525"},{"key":"S0007114584000337_manual_ref-2","doi-asserted-by":"publisher","DOI":"10.1042\/bj1580079"},{"key":"S0007114584000337_manual_ref-9","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19770068"},{"key":"S0007114584000337_manual_ref-10","first-page":"160","volume":"69","author":"Denkla","year":"1967","journal-title":"Journal of Laboratory Clinical Medicine"},{"key":"S0007114584000337_manual_ref-1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1500511"},{"key":"S0007114584000337_manual_ref-16","first-page":"197","volume-title":"Finfish Nutrition and Fishfeed Technology","author":"Kaushik","year":"1979"},{"key":"S0007114584000337_manual_ref-25","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/111.1.46"},{"key":"S0007114584000337_manual_ref-20","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19830079"},{"key":"S0007114584000337_manual_ref-8","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/111.9.1556"},{"key":"S0007114584000337_manual_ref-4","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(77)90251-2"},{"key":"S0007114584000337_manual_ref-14","first-page":"229","volume":"24","author":"Halver","year":"1965","journal-title":"Federation Proceedings"},{"key":"S0007114584000337_manual_ref-21","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/107.8.1361"},{"key":"S0007114584000337_manual_ref-24","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-163-40795"},{"key":"S0007114584000337_manual_ref-15","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(82)90199-7"},{"key":"S0007114584000337_manual_ref-22","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/93.1.21"},{"key":"S0007114584000337_manual_ref-33","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/103.12.1756"},{"key":"S0007114584000337_manual_ref-26","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/111.11.1942"},{"key":"S0007114584000337_manual_ref-19","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19810086"},{"key":"S0007114584000337_manual_ref-18","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/105.7.861"},{"key":"S0007114584000337_manual_ref-11","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)84513-1"},{"key":"S0007114584000337_manual_ref-13","doi-asserted-by":"publisher","DOI":"10.1042\/bj1560657"},{"key":"S0007114584000337_manual_ref-3","first-page":"361","volume":"72","author":"Barash","year":"1982","journal-title":"Cornell Veterinarian"},{"key":"S0007114584000337_manual_ref-29","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/108.10.1595"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114584000337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:44:34Z","timestamp":1750466674000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114584000337\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1984,5]]}},"alternative-id":["S0007114584000337"],"URL":"https:\/\/doi.org\/10.1079\/bjn19840032","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,3]]}}}