{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:53:07Z","timestamp":1761807187340},"reference-count":39,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":7191,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1987,7]]},"abstract":"<jats:p>1. In Expt 1, fractional synthesis rates (FSR) of tissue protein were measured along the gastrointestinal tract (GIT) of six 1-week-old, milk-fed lambs by using a large amount of L-[3,4(n)-<jats:sup>3<\/jats:sup>H]valine.<\/jats:p><jats:p>2. In Expt 2, eighteen lambs were used to determine the fractional growth rate (FGR) of gastrointestinal tissue protein.<\/jats:p><jats:p>3. FSR<jats:sub>Minimum(Min)<\/jats:sub> and FSR<jats:sub>Maximum(Max)<\/jats:sub> were calculated assuming plasma or tissue homogenate free valine specific radioactivity was representative of the valine precursor pool for protein synthesis. There were no significant differences between FSR<jats:sub>(Min)<\/jats:sub> and FSR<jats:sub>(Max)<\/jats:sub> in any gastrointestinal tissue of lambs used in Expt 1 (P &gt; 0.05). FSR gradually and significantly (P &gt; 0.05) increased from the oesophagus (FSR<jats:sub>(Max)<\/jats:sub>26.5%\/d). reticulo-rumen (30.1%\/d), omasum (41.0%\/d) and abomasum (56.1%\/d) to small intestine (87.5%\/d), and then declined significantly (P &lt; 0.05) towards the caecum (45.2%\/d) and the colon (38.4%\/d). No significant differences were observed between FSR in the duodenum, jejunum or ileum (P &gt; 0.05).<\/jats:p><jats:p>4. FGR ranged from 2,6%\/d in the oesophagus to 8,7%\/d in the omasum. The ratio, FGR:FSR, which reflected the efficiency of protein deposition, was at a maximum in the stomachs and caecum and at a minimum in the small intestine.<\/jats:p><jats:p>5. The relative contribution of the oesophagus, stomachs, small intestine and large intestine to GIT protein synthesis was 1, 13, 76 and 10% respectively. The GIT accounted for approximately 11.5% of whole-body protein synthesis.<\/jats:p>","DOI":"10.1079\/bjn19870079","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T00:07:20Z","timestamp":1126915640000},"page":"159-169","source":"Crossref","is-referenced-by-count":18,"title":["Protein synthesis and growth in the gastrointestinal tract of the young preruminant lamb"],"prefix":"10.1017","volume":"58","author":[{"given":"D.","family":"Attaix","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Arnal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S0007114587000813_ref035","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19850013"},{"key":"S0007114587000813_ref033","volume-title":"M\u00e9thodes 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