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Quantitatively the duodenum was the most significant site of biotin absorption when crystalline biotin was included in the diet and when dietary ingredients contained highly available biotin. In contrast, when diets of low biotin availability were given the distal segments of the small intestine contributed a relatively greater amount to biotin absorption. During passage of digesta from the ileum to the caecum there was a tenfold increase in biotin concentration. About half the amount was of ileal origin with the remainder presumably resulting from microbial synthesis. About 20% of caecal biotin was in a \u2018free\u2019 form but the degree of absorption from the caeca was not determined. The amount of biotin disappearing from the gut of birds given maize-based diets was similar to the quantity appearing in portal blood. Biotin absorption was not detected from wheat-based diets using arteriovenous differences.<\/jats:p>","DOI":"10.1079\/bjn19890039","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T04:07:20Z","timestamp":1126930040000},"page":"389-398","source":"Crossref","is-referenced-by-count":13,"title":["Intestinal distribution and absorption of biotin in the chicken"],"prefix":"10.1017","volume":"62","author":[{"given":"W. 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