{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:44:38Z","timestamp":1789627478033,"version":"build-2803163510"},"reference-count":34,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":5668,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1991,9]]},"abstract":"<jats:p>Twelve lambs, paired on the basis of live weight, were cannulated in the abomasum, in the proximal jejunum approximately 4 m distal to the pylorus and in the terminal ileum. Six were infected with 3000 <jats:italic>Trichostrongylus colubriformis<\/jats:italic> and 3000 <jats:italic>Ostertagia circumcincta<\/jats:italic> larvae each day for 18 weeks and the remainder were pair-fed to individual infected lambs. All animals were offered ryegrass (<jats:italic>Lolium perenne<\/jats:italic>)\u2013white clover (<jats:italic>Trifolium repens<\/jats:italic>) pasture, cut daily. Dry matter (DM) intake, live weight, faecal egg concentration, plasma pepsinogen and plasma protein concentrations were measured weekly. During weeks 7 and 17 after commencement of infection, the flow of digesta along the gastrointestinal tract was measured together with enteric plasma loss and true digestion and absorption of <jats:sup>125<\/jats:sup>I-labelled albumin in the small intestine. DM intake was depressed by parasitism, being 1331, (se 70), 423 (se 32) and 529 (se 52) g\/d during weeks 3, 7 and 17 respectively. The flow of nitrogen at the proximal jejunum and in faeces was increased by parasitism during week 7 and at the abomasum and ileum during week 17. Plasma protein-N loss (g\/d) into the gastrointestinal tract was 0.68 (se 0.091) and 1.97 (se 0.139) during week 7, and 0.85 (se0.158) and 1.96 (se 0.396) during week 17, in control and infected sheep respectively. True digestion and absorption of albumin in the proximal small intestine, the site of infection, was very low (mean 0.08) and was not affected by parasitism. Between the abomasum and terminal ileum absorption of albumin was high (mean 0.87) and again was not affected by parasitism. It was calculated that of the total increase in endogenous protein passing from the ileum tract as a result of infection, plasma protein comprised only a small percentage (10\u201336%). The major proportion of digestion and absorption of protein occurred in the distal small intestine beyond the site of infection and was not affected by infection.<\/jats:p>","DOI":"10.1079\/bjn19910028","type":"journal-article","created":{"date-parts":[[2005,5,19]],"date-time":"2005-05-19T19:49:52Z","timestamp":1116532192000},"page":"237-249","source":"Crossref","is-referenced-by-count":33,"title":["Nitrogen transactions along the digestive tract of lambs concurrently infected with <i>Trichostrongylus colubriformis<\/i> and <i>Ostertagia circumcincta<\/i>"],"prefix":"10.1017","volume":"66","author":[{"given":"M. D.","family":"Bown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. P.","family":"Poppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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