{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:20:36Z","timestamp":1787167236267,"version":"build-2736575974"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":4999,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1993,7]]},"abstract":"<jats:p>\n                    Sheep fed\n                    <jats:italic>ad lib<\/jats:italic>\n                    . on a good-quality pelleted diet (g\/kg; hay 500, barley 300, molasses, fish meal and minerals) were infused via the hepatic portal vein with mixtures of the sodium salts of volatile fatty acids, acetate and propionate, and a variety of equivalent osmotic loads. Propionate infused at rates between 0\u00b76 and 2\u00b75 mmol\/min consistently reduced food intake in a linear, dose-related manner. Propionate infusions resulted in consistent dose-related increases in peripheral venous plasma glucose concentration but variable changes in insulin concentration. Infusion of osmotically balanced mixtures of propionate, acetate, mannitol or saline (9 g NaCI\/I) indicated that at constant osmotic loading propionate caused a greater reduction in intake than other infusions. Acetate infusions only depressed food intake when administered as a 1 M solution. Lower concentrations had little effect, similar to that of equivalent osmotic loads of mannitol or saline. It is concluded that portal propionate flow has a potential role in the control of food intake in ruminants which is independent of osmotic effects or changes in plasma insulin concentration.\n                  <\/jats:p>","DOI":"10.1079\/bjn19930103","type":"journal-article","created":{"date-parts":[[2005,6,11]],"date-time":"2005-06-11T14:09:04Z","timestamp":1118498944000},"page":"37-46","source":"Crossref","is-referenced-by-count":59,"title":["The role of propionate and acetate in the control of food intake in sheep"],"prefix":"10.1017","volume":"70","author":[{"given":"D. A. H.","family":"Farningham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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