{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:55:54Z","timestamp":1770062154993,"version":"3.49.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":4572,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1994,9]]},"abstract":"<jats:p>Changes in the concentrations of glucosinolates from rapeseed meal and some glucosinolate degradation products during incubation <jats:italic>in vitro<\/jats:italic> with myrosinase (<jats:italic>EC<\/jats:italic> 3.2.3.1), with pepsin (<jats:italic>EC<\/jats:italic> 3.4.23.1)\u2013HCI, and with contents of porcine small intestine and caecum were studied. When rapeseed meal was incubated with myrosinase, 5-vinyl oxazolidinethione (OZT) and butenyl and pentenyl isothiocyanates were produced; OZT concentration rose to a plateau after about 2 h. However, when incubated with caecal contents only OZT could be detected; its concentration peaked after about 4\u20135 h then declined. Under <jats:italic>in vitro<\/jats:italic> conditions whirh attempted to simulate peptic and small intestinal digestion no OZT could be detected; the individual glucosinolates differed in susceptibility to peptic conditions, losses ranging from 3 to 23%. Under the small intestinal conditions the losses of individual glucosinolates ranged from about 7 to 28%. Addition of CuSO<jats:sub>4<\/jats:sub>, ascorbic acid, tylosin or a probiotic had little effect on the outcome of peptic or small intestinal incubations but tylosin appeared tc slow the degradation of glucosinolates in the presence of caecal contents.<\/jats:p>","DOI":"10.1079\/bjn19940047","type":"journal-article","created":{"date-parts":[[2005,6,9]],"date-time":"2005-06-09T07:49:51Z","timestamp":1118303391000},"page":"455-466","source":"Crossref","is-referenced-by-count":31,"title":["Degradation of glucosinolates during in <i>vitro<\/i> incubations of rapeseed meal with myrosinase (<i>EC<\/i> 3.2.3 1) and with pepsin (<i>EC<\/i> 3.4.23.l)\u2013hydrochloric acid, and contents of porcine small intestine and caecum"],"prefix":"10.1017","volume":"72","author":[{"given":"Ian","family":"Maskell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Smithard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S0007114594000486_ref006","doi-asserted-by":"publisher","DOI":"10.2527\/jas1974.39157x"},{"key":"S0007114594000486_ref005","first-page":"823","article-title":"Decomposition of sinalbin. 11. The decomposition products of sinalbin and their degradation pathways","volume":"31","author":"Kawakishi","year":"1967","journal-title":"Agricultural and Biological Chemistry"},{"key":"S0007114594000486_ref003","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.2740370805"},{"key":"S0007114594000486_ref004","first-page":"172","volume-title":"Handbuch der Tierernahrung","author":"Hill","year":"1969"},{"key":"S0007114594000486_ref002","first-page":"1","volume-title":"Proceedings of the Second Spring Conference","author":"Duncan","year":"1991"},{"key":"S0007114594000486_ref008","unstructured":"Maskell I. (1990). Nutritional aspects of feeding rapeseed products to rats and pigs. PhD Thesis, University of Newcastle upon Tyne."},{"key":"S0007114594000486_ref012","doi-asserted-by":"publisher","DOI":"10.4141\/cjas87-117"},{"key":"S0007114594000486_ref001","doi-asserted-by":"publisher","DOI":"10.1021\/bi00866a041"},{"key":"S0007114594000486_ref013","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.2740420404"},{"key":"S0007114594000486_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)84863-3"},{"key":"S0007114594000486_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0377-8401(91)90131-B"},{"key":"S0007114594000486_ref010","first-page":"427","article-title":"Antinutrients in rapeseeds","volume":"59","author":"Pusztai","year":"1989","journal-title":"Nutrition Abstracts and Reviews Series"},{"key":"S0007114594000486_ref007","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0034-5288(18)34951-8","author":"Kidder","year":"1961","journal-title":"Research in Veterinary Science"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0007114594000486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T03:13:52Z","timestamp":1557890032000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0007114594000486\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,9]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1994,9]]}},"alternative-id":["S0007114594000486"],"URL":"https:\/\/doi.org\/10.1079\/bjn19940047","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,9]]}}}