{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T04:24:34Z","timestamp":1774585474857,"version":"3.50.1"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2007,7,24]],"date-time":"2007-07-24T00:00:00Z","timestamp":1185235200000},"content-version":"unspecified","delay-in-days":3766,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1997,4]]},"abstract":"<jats:p>Effects of different dietary fats on plasma, hepatic and biliary lipids were determined in male golden Syrian hamsters (<jats:italic>Mesocricetus auratus<\/jats:italic>) fed on purified diets for 7 weeks. Diets were made by blending different fats containing characteristic fatty acids: butter (14:0 + 16:0), palm stearin (16:0), coconut oil (12:0 + 14:0), rapeseed oil (18:1), olive oil (18:l) and sunflowerseed oil (18:2). In all diets except the sunflowerseed oil diet dietary 18:2 was held constant at 2% energy. Total fat supplied 12% of energy and cholesterol was added at 4 g\/kg diet. Plasma cholesterol and triacyglycerol concentrations were increased by dietary cholesterol. After 7 weeks, plasma cholesterol concentrations were highest with the palm Stearin, coconut oil and olive oil diets (8\u00b79, 8\u00b79 and 9\u00b72 mmol\/l) and lowest with the rapeseed oil and sdowerseed oil diets (6\u00b77 and 5\u00b75 mmol\/l) while the butter diet was intermediate (8\u00b75 mmol\/l). Hepatic cholesterol concentration was highest in hamsters fed on the olive oil diet and lowest with the palm stearin diet (228<jats:italic>v<\/jats:italic>. 144 \u00b5mol\/g liver). Biliary lipids, lithogenic index and bile acid profile of the gall-bladder bile did not differ significantly among the six diets. Although the gallstone incidence was generally low in this study, three out of 10 hamsters fed on the palm stearin diet developed cholesterol gallstones. In contrast, no cholesterol gallstones were found with the other diets. Rapeseed and dowerseed oils caused the lowest plasma cholesterol and triacyglycerol concentrations whereas olive oil failed to demonstrate a cholesterol-lowering effect compared with diets rich in saturated fatty acids. Since 18:2 was kept constant at 2% of energy in all diets, the different responses to rapeseed and olive oils could possibly be attributed to their different contents of 16:0 (5\u00b76 %<jats:italic>v<\/jats:italic>. 12\u00b78% respectively). Other possible explanations are discussed.<\/jats:p>","DOI":"10.1079\/bjn19970060","type":"journal-article","created":{"date-parts":[[2005,9,17]],"date-time":"2005-09-17T04:07:20Z","timestamp":1126930040000},"page":"605-620","source":"Crossref","is-referenced-by-count":25,"title":["Effect of dietary fats rich in lauric, myristic, palmitic, oleic or linoleic acid on plasma, hepatic and biliary lipids in cholesterol-fed hamsters"],"prefix":"10.1017","volume":"77","author":[{"given":"Elke 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