{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:54:18Z","timestamp":1765727658200},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2007,3,9]],"date-time":"2007-03-09T00:00:00Z","timestamp":1173398400000},"content-version":"unspecified","delay-in-days":3568,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nutr"],"published-print":{"date-parts":[[1997,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To investigate the chronological changes in conjunctival epithelium after supplementation with a massive oral dose of vitamin A, conjunctival impression cytology (CIC) with transfer was carried out repeatedly among 200 children aged 6\u2013120 months in a randomized, double-blind, placebo-controlled study in Chandigarh (India). Significant conversion to normal CIC started 71\u201380 d after vitamin A supplementation and by 101\u2013110d conversion had taken place in all children. Compared with the placebo group, plasma retinol concentration at 100d post-supplement was found to be significantly higher in the vitamin A-supplemented group P = 0\u00b704. This study demonstrates that CIC responds to a massive oral dose of vitamin A 3\u20134 months after supplementation. These findings should guide future studies and evaluations in which CIC is used to assess response to vitamin A interventions.<\/jats:p>","DOI":"10.1079\/bjn19970085","type":"journal-article","created":{"date-parts":[[2005,6,9]],"date-time":"2005-06-09T07:49:51Z","timestamp":1118303391000},"page":"863-869","source":"Crossref","is-referenced-by-count":3,"title":["Dynamics of conjunctival impression cytologic changes after vitamin A supplementation"],"prefix":"10.1017","volume":"77","author":[{"given":"Swapan","family":"Chowdhury","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. K.","family":"Ganguly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minni","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lata","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. N. S.","family":"Walia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,3,9]]},"reference":[{"key":"S000711459700086X_ref006","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1987.01060090082033"},{"key":"S000711459700086X_ref008","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/clinchem\/34.2.377","article-title":"Concurrent liquid chromatographic assay of retinol, \u03b1-tocopherol, \u03b2-carotene, \u03b1-carotene, lycopene and \u03b2-cryptoxanthin in plasma with tocopherol acetate as internal standard","volume":"34","author":"Thurnham","year":"1988","journal-title":"Clinical Chemistry"},{"key":"S000711459700086X_ref010","volume-title":"Periodic, Large Oral Doses of Vitamin A for the Prevention of Vitamin A Deficiency and Xerophthalmia: A Summary of Experiences. A Report of the International Vitamin A Consultative Group","author":"West","year":"1987"},{"key":"S000711459700086X_ref001","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/ajcn\/47.5.875","article-title":"Impression cytology detects subclinical vitamin A deficiency","volume":"47","author":"Amedee-Manesme","year":"1988","journal-title":"American Journal of Clinical Nutrition"},{"key":"S000711459700086X_ref003","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19920110"},{"key":"S000711459700086X_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90266-8"},{"key":"S000711459700086X_ref005","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1093\/ajcn\/48.3.695","article-title":"Impression cytology: a practical index of vitamin A status","volume":"48","author":"Natadisastra","year":"1988","journal-title":"American Journal of Clinical Nutrition"},{"key":"S000711459700086X_ref002","first-page":"122","volume-title":"Interpretation and Uses of Medical Statistics","author":"Bourke","year":"1985"},{"key":"S000711459700086X_ref004","first-page":"166","article-title":"Impression cytology with transfer. An easy method for detection of vitamin A deficiency","volume":"58","author":"Luzeau","year":"1988","journal-title":"International Journal for Vitamin and Nutrition Research"},{"key":"S000711459700086X_ref007","first-page":"1439","article-title":"Serum levels of vitamin A and carotenoids as reflectors of nutritional status","volume":"73","author":"Olson","year":"1984","journal-title":"Journal of the National Cancer Institute"}],"container-title":["British Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S000711459700086X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T15:43:56Z","timestamp":1586274236000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S000711459700086X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1997,6]]}},"alternative-id":["S000711459700086X"],"URL":"https:\/\/doi.org\/10.1079\/bjn19970085","relation":{},"ISSN":["0007-1145","1475-2662"],"issn-type":[{"value":"0007-1145","type":"print"},{"value":"1475-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,6]]}}}