{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:57:09Z","timestamp":1777435029409,"version":"3.51.4"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"unspecified","delay-in-days":7347,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Helminthol."],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The mouse bile duct tapeworm <jats:italic>Hymenolepis microstoma<\/jats:italic> requires beetles as the obligatory intermediate host. However, when congenitally athymic NMRI-<jats:italic>nu<\/jats:italic> mice were infected with the mature tapeworm and allowed to eat their own faeces with tapeworm eggs, the oncospheres penetrated the intestinal tissue and developed to cysticercoids. After excysting, growth to adult worms occurs in the lumen of the small intestine and bile duct. Furthermore, the same happened when NMRI-<jats:italic>nu<\/jats:italic> mice, non-obese diabetic severe combined immunodeficiency (NOD\/Shi-<jats:italic>scid<\/jats:italic>) mice and NOD\/Shi-<jats:italic>scid<\/jats:italic>, IL-2 R\u03b3<jats:sup>null<\/jats:sup> (NOG) mice were orally inoculated with shell-free eggs of this parasite. Differences between the cysticercoids of <jats:italic>H. microstoma<\/jats:italic> and <jats:italic>H. nana<\/jats:italic> developed in the mouse intestinal tissues were: (i) the time course for the development of fully matured cysticercoids of <jats:italic>H. microstoma<\/jats:italic> in mice was about 11 days but only 4 days for <jats:italic>H. nana<\/jats:italic>; and (ii) cysticercoids of <jats:italic>H. microstoma<\/jats:italic> developed in mice had a tail while those of <jats:italic>H. nana<\/jats:italic> had none.<\/jats:p>","DOI":"10.1079\/joh2003207","type":"journal-article","created":{"date-parts":[[2004,2,28]],"date-time":"2004-02-28T01:33:07Z","timestamp":1077931987000},"page":"1-5","source":"Crossref","is-referenced-by-count":21,"title":["<i>Hymenolepis microstoma<\/i>: direct life cycle in immunodeficient mice"],"prefix":"10.1017","volume":"78","author":[{"given":"J.","family":"Andreassen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nakaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"S0022149X00702690_ref013","first-page":"549","article-title":"Development of Hymenolepis nana and Hymenolepis diminuta (Cestoda: Hymenolepididae) in the intermediate host Tribolium confusum","volume":"59","author":"Voge","year":"1957","journal-title":"University of California Publications in Zoology"},{"key":"S0022149X00702690_ref001","doi-asserted-by":"publisher","DOI":"10.2307\/3276089"},{"key":"S0022149X00702690_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00012086"},{"key":"S0022149X00702690_ref010","volume-title":"CRC handbook of tapeworm identification","author":"Schmidt","year":"1986"},{"key":"S0022149X00702690_ref012","doi-asserted-by":"publisher","DOI":"10.2307\/3276032"},{"key":"S0022149X00702690_ref004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1989.tb00681.x"},{"key":"S0022149X00702690_ref006","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701343"},{"key":"S0022149X00702690_ref003","first-page":"345","article-title":"Photomicroscopic observation of infective cysticercoid and the earlier stages of Hymenolepis nana isolated from the mouse intestine","volume":"26","author":"Ito","year":"1977","journal-title":"Japanese Journal of Parasitology"},{"key":"S0022149X00702690_ref011","doi-asserted-by":"publisher","DOI":"10.2307\/3279462"},{"key":"S0022149X00702690_ref002","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.158.8.3578"},{"key":"S0022149X00702690_ref014","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.1.204"},{"key":"S0022149X00702690_ref009","doi-asserted-by":"publisher","DOI":"10.1084\/jem.189.10.1601"},{"key":"S0022149X00702690_ref005","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2001-12-0207"},{"key":"S0022149X00702690_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182097001741"}],"container-title":["Journal of Helminthology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0022149X00702690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T02:30:02Z","timestamp":1712889002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0022149X00702690\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0022149X00702690"],"URL":"https:\/\/doi.org\/10.1079\/joh2003207","relation":{},"ISSN":["0022-149X","1475-2697"],"issn-type":[{"value":"0022-149X","type":"print"},{"value":"1475-2697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}