{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T13:00:52Z","timestamp":1769605252253,"version":"3.49.0"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"2b","license":[{"start":{"date-parts":[[2007,9,27]],"date-time":"2007-09-27T00:00:00Z","timestamp":1190851200000},"content-version":"unspecified","delay-in-days":2370,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2001,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                    <jats:p>Iodine deficiency disorders (IDD) are related to the degree of iodine\n                        deficiency. In european countries, characterized by mild to moderate iodine\n                        deficiency, neurological deficits or minor neuropsychological impairments\n                        have been described. Urinary iodine excretion (UIE) ranged from 30 to 170\n                        mcg\/L, 141 millions of people were at risk of IDD, 97 millions were affected\n                        by goiter and 0.9 millions had an impaired mental development.<\/jats:p>\n                    <jats:p>Iodine prophylaxis is devoid of adverse reactions with the exception of\n                        sporadic cases of transitory hyperthyroidism, associated to the severity of\n                        iodine deficiency before the prophylaxis. The International Council for\n                        Control of IDD recommends an universal iodine prophylaxis, instituted\n                        gradually in severe iodine deficient countries. The total cost of universal\n                        iodine prophylaxis is very cheap compared to the social cost of goiter and\n                        cretinism.<\/jats:p>\n                    <jats:p>In conclusion, most european countries are still characterized by mild\n                        to moderate iodine deficiency. Iodine prophylaxis programs are already\n                        operating, its cost is irrelevant with respect to the undebatable beneficial\n                        impact on the health. Adverse effects are not observed except in severe\n                        iodine deficient areas where iodine intake was abruptly increased.<\/jats:p>","DOI":"10.1079\/phn2001138","type":"journal-article","created":{"date-parts":[[2008,6,3]],"date-time":"2008-06-03T14:03:09Z","timestamp":1212501789000},"page":"529-535","source":"Crossref","is-referenced-by-count":46,"title":["Iodine deficiency disorders in Europe"],"prefix":"10.1017","volume":"4","author":[{"given":"Paolo","family":"Vitti","sequence":"first","affiliation":[{"name":"Universit\u00e0 di Pisa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Rago","sequence":"additional","affiliation":[{"name":"Universit\u00e0 di Pisa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Aghini-Lombardi","sequence":"additional","affiliation":[{"name":"Universit\u00e0 di Pisa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Pinchera","sequence":"additional","affiliation":[{"name":"Universit\u00e0 di Pisa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,9,27]]},"reference":[{"key":"S1368980001001446_manual_ref-10","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-70-2-379"},{"key":"S1368980001001446_manual_ref-14","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-1245-9_53"},{"key":"S1368980001001446_manual_ref-27","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1999.9.545"},{"key":"S1368980001001446_manual_ref-6","doi-asserted-by":"publisher","DOI":"10.1210\/endo.132.4.8462484"},{"key":"S1368980001001446_manual_ref-26","unstructured":"26 WHO-ICCIDD-UNICEF. Multicentre study to assess the\n                            impact of salt iodization level on iodine status.\n                            1997."},{"key":"S1368980001001446_manual_ref-20","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412293312603"},{"key":"S1368980001001446_manual_ref-19","first-page":"497","article-title":"Iodized salt prophylaxis of endemic goiter: an experience in\n                            Toscana (Italy)","volume":"129","author":"Aghini Lombardi","year":"1993","journal-title":"Acta. Endocrinol."},{"key":"S1368980001001446_manual_ref-7","doi-asserted-by":"publisher","DOI":"10.1007\/BF03349700"},{"key":"S1368980001001446_manual_ref-28","first-page":"70","volume-title":"Salt Iodization for the elimination of iodine deficiency.\n                            ICCIDD UNICEF","author":"Mannar","year":"1995"},{"key":"S1368980001001446_manual_ref-3","first-page":"215","volume-title":"Towards the eradication of endemic goiter, cretinism and\n                            iodine deficiency","author":"Dunn","year":"1986"},{"key":"S1368980001001446_manual_ref-11","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-0765-5_25"},{"key":"S1368980001001446_manual_ref-23","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92095-1"},{"key":"S1368980001001446_manual_ref-4","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1994.4.107"},{"key":"S1368980001001446_manual_ref-9","doi-asserted-by":"publisher","DOI":"10.1007\/BF03350696"},{"key":"S1368980001001446_manual_ref-13","unstructured":"13 World Health Organization, United Nations\n                            Children's Found and International Council for Control of Iodine\n                            Deficiency Disorders; Elimination of iodine deficiency disorder (IDD) in\n                            Central and Eastern Europe, the Commonwealth of Independent States and\n                            the Baltic States. Proceedings of a conference held in Munich Germany\n                            3\u20136 September 1997. WHO\/EURO\/NUT\/98.1."},{"key":"S1368980001001446_manual_ref-16","first-page":"20","article-title":"Endemic goiter in Finland and changes during 30years of\n                            iodine prophylaxis","author":"Lamberg","year":"1986","journal-title":"Endocrinol. Exper."},{"key":"S1368980001001446_manual_ref-15","first-page":"561","article-title":"The spectrum of thyroid disorders in an iodine deficient\n                            community: the Pescopagano survey","volume":"84","author":"Aghini-Lombardi","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"S1368980001001446_manual_ref-22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)90194-4"},{"key":"S1368980001001446_manual_ref-17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1991.tb00368.x"},{"key":"S1368980001001446_manual_ref-8","first-page":"293","volume-title":"The Damaged Brain of Iodine Deficiency","author":"Chiovato","year":"1994"},{"key":"S1368980001001446_manual_ref-25","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1320546"},{"key":"S1368980001001446_manual_ref-18","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1360180"},{"key":"S1368980001001446_manual_ref-2","unstructured":"2 Indicators for assessing Iodine Deficiency Disorder\n                            and their control through salt iodization.\n                            WHO\/NUT\/94.6."},{"key":"S1368980001001446_manual_ref-5","doi-asserted-by":"publisher","DOI":"10.1007\/BF03349967"},{"key":"S1368980001001446_manual_ref-21","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-41-2-221"},{"key":"S1368980001001446_manual_ref-1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90636-0"},{"key":"S1368980001001446_manual_ref-24","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)91188-5"},{"key":"S1368980001001446_manual_ref-12","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-1245-9"}],"container-title":["Public Health Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1368980001001446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T10:30:52Z","timestamp":1756204252000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1368980001001446\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":28,"journal-issue":{"issue":"2b","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["S1368980001001446"],"URL":"https:\/\/doi.org\/10.1079\/phn2001138","relation":{},"ISSN":["1368-9800","1475-2727"],"issn-type":[{"value":"1368-9800","type":"print"},{"value":"1475-2727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}