{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T13:11:19Z","timestamp":1755695479613},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"6a","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Current interest in preventive nutritional supplementation strategies during the reproductive cycle in developed countries focuses mainly on iron and folic acid. Iron deficiency is the most common cause of anaemia. Inadequate iron nutrition is mainly a problem in developing countries but it also seems to affect a large proportion of pregnant women in the industrialised world. There is no chance for diet modification alone to meet iron requirements during pregnancy. However, dietary advice must be provided to increase iron intake and iron bioavailability. The best choice is prescribed supplementation adapted to the individual's needs.<\/jats:p><jats:p>Folic Acid supplementation during the periconceptional period reduces the occurrence and recurrence of neural tube defects (NTDs). According to the updated edition of American Dietary Reference Intakes, recommended dietary allowance for folate for women of childbearing age varies throughout the reproductive cycle from 400 \u03bcg day<jats:sup>\u22121<\/jats:sup> of dietary folate equivalents (DFEs) for non-pregnant women, to 600 \u03bcg day<jats:sup>\u22121<\/jats:sup> DFEs for pregnant women and 500 \u03bcg day<jats:sup>\u22121<\/jats:sup> DFEs in lactating women. Increasing dietary folate, fortifying staple foods with folic acid or use of folic acid supplements can increase folate intake.<\/jats:p>","DOI":"10.1079\/phn2001219","type":"journal-article","created":{"date-parts":[[2003,2,26]],"date-time":"2003-02-26T12:47:22Z","timestamp":1046263642000},"page":"1363-1366","source":"Crossref","is-referenced-by-count":5,"title":["Preventive nutritional supplementation throughout the reproductive life cycle"],"prefix":"10.1017","volume":"4","author":[{"given":"Joan","family":"Fern\u00e1ndez-Ballart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle M","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2001,4,1]]},"reference":[{"key":"S1368980001000350_ref021","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990521)84:2<151::AID-AJMG12>3.0.CO;2-T"},{"key":"S1368980001000350_ref019","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530210052030"},{"key":"S1368980001000350_ref018","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7753(00)71316-9"},{"key":"S1368980001000350_ref017","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1600467"},{"key":"S1368980001000350_ref014","first-page":"1","article-title":"Recommendations for the use of folic acid to reduce the number of spina bifida cases and other neural tube defects","volume":"41","year":"1992","journal-title":"MMWR Morb. 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