{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T12:53:45Z","timestamp":1770987225562,"version":"3.50.1"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2007,1,2]],"date-time":"2007-01-02T00:00:00Z","timestamp":1167696000000},"content-version":"unspecified","delay-in-days":700,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Public Health Nutr."],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1368980005000066_sec01\"><jats:title>Background<\/jats:title><jats:p>In areas where vitamin A deficiency (VAD) is prevalent, vitamin A repletion reduces child mortality by 23% on average.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980005000066_sec02\"><jats:title>Objectives<\/jats:title><jats:p>To estimate the potential child survival benefits of policies and programmes aimed at controlling VAD in Mozambique, and to make policy and programme recommendations.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980005000066_sec03\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>The potential contribution of VAD to child mortality in Mozambique was estimated by combining the observed VAD prevalence in the under-5s (71.2%), the measured child mortality effects of VAD (risk of death in children with VAD = 1.75 times higher than in children without VAD) and the observed under-5 mortality rate in the country (210 per 1000 live births).<\/jats:p><\/jats:sec><jats:sec id=\"S1368980005000066_sec04\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In Mozambique, an estimated 2.3 million children below the age of 5 years are vitamin-A-deficient. In the absence of appropriate policy and programme action, VAD will be the attributable cause of over 30 000 deaths annually in the under-5s. This represents 34.8% of all-cause mortality in this age group.<\/jats:p><\/jats:sec><jats:sec id=\"S1368980005000066_sec05\" sec-type=\"discussion\"><jats:title>Discussion<\/jats:title><jats:p>Vitamin A supplementation (VAS) has been adopted as a short- to medium-term strategy to control VAD in children, and is integrated into routine child health services. However, the last VAS coverage survey showed that only 46% of children received a vitamin A supplement in the 6 months preceding the survey. If VAS coverage is to increase significantly in the foreseeable future, four areas appear to be of paramount importance: (1) reduce missed opportunities for VAS such as visits of sick children to child health services and community outreach activities; (2) take advantage of all potential opportunities for accelerating VAS coverage, such as additional vaccination campaigns and emergency response activities; (3) strengthen health workers\u2019 training, supervision and monitoring skills; and (4) increase community demand for VAS of children. Biannual VAS, as the primary component of an integrated strategy for VAD control in children, has the promise to be among the most cost-effective\/high-impact child survival interventions in Mozambique.<\/jats:p><\/jats:sec>","DOI":"10.1079\/phn2005664","type":"journal-article","created":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T03:56:58Z","timestamp":1107835018000},"page":"29-31","source":"Crossref","is-referenced-by-count":34,"title":["Vitamin A deficiency and child mortality in Mozambique"],"prefix":"10.1017","volume":"8","author":[{"given":"Victor M","family":"Aguayo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Kahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Ismael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Meershoek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2007,1,2]]},"reference":[{"key":"S1368980005000066_ref008","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1600398"},{"key":"S1368980005000066_ref007","volume-title":"Community-based Strategies for Breastfeeding Promotion and Support in Developing Countries","year":"2003"},{"key":"S1368980005000066_ref009","volume-title":"Can Food-Based Strategies Help Reduce Vitamin A and Iron Deficiencies? A Review of Recent Evidence","author":"Ruel","year":"2001"},{"key":"S1368980005000066_ref002","unstructured":"2 Ismael, C , Khan, SG , Thompson, R , Meershoek, S , Van Streirteghem, V . Inqu\u00e9rito nacional sobre a defici\u00eancia de vitamina A e preval\u00eancia de anemia e mal\u00e1ria em crian\u00e7as dos 6\u201359 meses e respectivas m\u00e3es. Maputo: MISAU \u2013 Reparti\u00e7\u00e3o de Nutri\u00e7\u00e3o e Instituto Nacional de Sa\u00fade, Helen Keller International and United Nations Children's Fund, 2003."},{"key":"S1368980005000066_ref005","volume-title":"The State of the World's Children 2002","year":"2002"},{"key":"S1368980005000066_ref003","volume-title":"Derivation of the Relative Risk of Child Mortality due to Vitamin A Deficiency","author":"Ross","year":"1996"},{"key":"S1368980005000066_ref004","volume-title":"Mo\u00e7ambique, Inqu\u00e9rito Demogr\u00e1fico e de Sa\u00fade 1997","author":"Da Costa Gaspar","year":"1998"},{"key":"S1368980005000066_ref001","volume-title":"Effectiveness of Vitamin A Supplementation in the Control of Young Child Morbidity and Mortality in Developing Countries","author":"Beaton","year":"1993"},{"key":"S1368980005000066_ref006","first-page":"80","article-title":"Contribution of breastfeeding to vitamin A nutrition of infants: a simulation model","volume":"81","author":"Ross","year":"2003","journal-title":"Bulletin of the World Health Organization"}],"container-title":["Public Health Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1368980005000066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T02:38:57Z","timestamp":1660185537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1368980005000066\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":9,"aliases":["10.1079\/phn2004664"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S1368980005000066"],"URL":"https:\/\/doi.org\/10.1079\/phn2005664","relation":{},"ISSN":["1368-9800","1475-2727"],"issn-type":[{"value":"1368-9800","type":"print"},{"value":"1475-2727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}