{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:25:56Z","timestamp":1760898356423,"version":"3.38.0"},"reference-count":30,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Chirurgica Belgica"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1080\/00015458.2006.11679834","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T13:38:29Z","timestamp":1462369109000},"page":"55-58","source":"Crossref","is-referenced-by-count":17,"title":["Comparison of Topical Glyceryl Trinitrate Ointment and Oral Nifedipine in the Treatment of Chronic Anal Fissure"],"prefix":"10.1080","volume":"106","author":[{"given":"N. A.","family":"Mustafa","sequence":"first","affiliation":[{"name":"Department of General Surgery, Karadeniz Technical University, Faculty of Medicine","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Agaoglu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Karadeniz Technical University, Faculty of Medicine","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Cengiz","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Karadeniz Technical University, Faculty of Medicine","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"T\u00fcrkyilmaz","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Karadeniz Technical University, Faculty of Medicine","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Y\u00fccel","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Karadeniz Technical University, Faculty of Medicine","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,3,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","unstructured":"Khubchandail I. T. Reed J. F. Sequelae of internal sphincterotomy for chronic fissure in-ano. Br J Surg 1989 76: 431\u20134.","DOI":"10.1002\/bjs.1800760504"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Garcia Aguilar J. Belmonte C. Wong W. D. Lowry A. C. Madoff R. D. Open vs. closed sphincterotomy for chronic anal fissure: long-term results. Dis Colon Rectum 1996 39: 440\u20133.","DOI":"10.1007\/BF02054061"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","unstructured":"Cook T. A. Brading A. F. Mortensen N. J. M. Differences in contractile properties of anorectal smooth muscle and the effect of calcium channel blockade. Br J Surg 1999 86: 70\u20135.","DOI":"10.1046\/j.1365-2168.1999.00998.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","unstructured":"Cook T. A. Brading A. F. Mortensen N. J. M. Effects of nifedipine on anorectal smooth muscle in vitro. Dis Colon Rectum 1999 42: 782\u20137.","DOI":"10.1007\/BF02236936"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","unstructured":"MacLeod S. R. Evans J. Symptomatic care and nitroglycerin in the management of anal fissure. J Gastrointest 2002 6: 278\u201380.","DOI":"10.1016\/S1091-255X(01)00078-6"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","unstructured":"Carapeti E. A. Kamm M. A. Evans B. K. Philips R. Topical Diltiazem and bethanechol decrease anal sphincter pressure without side effects. Gut 1999 45: 719\u201322.","DOI":"10.1136\/gut.45.5.719"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","unstructured":"Pitt J. Daxon P. M. Hallan R. I. Boulos P. B. A double-blind randomized placebo-controlled trial of oral indoramin to treat chronic anal fissure. Colorectal Disease 2001 3: 165\u20138.","DOI":"10.1046\/j.1463-1318.2001.00227.x"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","unstructured":"Maria G. Cassetta E. Gul D. Brisinda G. Bentivogglo A. R. I. A comparison of botulinum toxin and saline for the treatment of chronic anal fissure. NEngl JMed 1998 338: 217\u201320.","DOI":"10.1056\/NEJM199801223380402"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","unstructured":"Birisinda G. Maria G. Bentivaglio A. R. Cassette E. Gui D. Albanase A. A comparison of injection of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure. N Eng J Med 1999 341: 65\u20139.","DOI":"10.1056\/NEJM199907083410201"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","unstructured":"Argov S. Levendovsky O. Open lateral sphincterotomy is still the best treatment for chronic anal fissure. Am J Surg 2000 179: 201\u20132.","DOI":"10.1016\/S0002-9610(00)00307-X"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","unstructured":"Pernikoff B. J. Eisenstat T. E. Rubin R. J. Oliver G. C. Selvati E. P. Reappraisal of partial lateral internal sphincterotomy. Dis Colon Rectum 1994 37: 1291\u20135.","DOI":"10.1007\/BF02257799"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","unstructured":"Richard C. S. Gregoire R. Plewes E. A. Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure: results of a randomized controlled trial by the Canadian Colorectal Surgical Trials Group. Dis Colon Rectum 2000 43: 1048\u201357.","DOI":"10.1007\/BF02236548"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","unstructured":"Jameson J. S. Chia Y. W. Kamm M. A. Speakman C. T. Chye Y. H. Henry M. M. Effect of age sex and parity on anorectal function. Br J Surg 1994 81: 1689\u201392.","DOI":"10.1002\/bjs.1800811143"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","unstructured":"O\u2019Kelly T. Brading A. Mortensen N. Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide. Gut 1993 34: 689\u201393.","DOI":"10.1136\/gut.34.5.689"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","unstructured":"Jonard P. Essamri B. Diltiazem and internal anal sphincter. Lancet 1987 1: 754.","DOI":"10.1016\/S0140-6736(87)90402-8"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","unstructured":"Lund J. N. Scholefield J. H. A prospective randomized double blind placebo-controlled trial of glyceryl trinitrate ointment treatment in anal fissure. Lancet 1997 349: 11\u20134.","DOI":"10.1016\/S0140-6736(96)06090-4"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","unstructured":"Kennedy M. L. Sowter S. Nguyen H. Lubowski D. Z. Glyceryl trinitrate ointment for the treatment of chronic anal fissure: Results of a placebo-controlled trial and long term follow-up. Dis Colon Rectum 1999 42: 1000\u20136.","DOI":"10.1007\/BF02236691"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","unstructured":"Loder P. B. Kamm M. A. Nicholls R. J. Phillips R. K. \u2018Reversible chemical sphincterotomy\u2019 by local application of glyceryl trinitrate. Br J Surg 1994 81: 1386\u20139.","DOI":"10.1002\/bjs.1800810949"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","unstructured":"Guillemot F. Lone Y. C. Leroi H. Lamblin M. D. Cortot A. Nitroglycerin in situ reduces upper anal canal pressure. Dig Dig Sci 1992 37: 155 (letter).","DOI":"10.1007\/BF01308361"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","unstructured":"Guillemot F. Leroi H. Lone Y. C. Rousseau C. G. Lamblin M. D. Cortot A. Action of in .situ nitroglycerin on upper anal canal pressure of patients with terminal constipation. A pilot study. Dis Colon Rectum 1993 36: 372\u20136.","DOI":"10.1007\/BF02053942"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","unstructured":"Knigt J. S. Birks M. Farouk R. Topical diltiazem ointment in the treatment of chronic anal fissure. Br J Surg 2001 88: 553\u20136.","DOI":"10.1046\/j.1365-2168.2001.01736.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"crossref","unstructured":"Carapeti E. A. Kamm M. A. Phillips R. K. Topical diltiazem and bethanechol decrease anal sphincter pressure and heal anal fissure without side effects. Dis Colon Rectum 2000 43: 1359\u201362.","DOI":"10.1007\/BF02236630"},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","unstructured":"Antropoli C. Perrotti P. Rubino M. Nifedipine for local use in conservative treatment of anal fissures: preliminary results of a multicenter study. Dis Colon Rectum 1999 42: 1011\u20135.","DOI":"10.1007\/BF02236693"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","unstructured":"Altomare D. F. Rinaldi M. Milito G. Glyceryl trinitrate for chronic anal fissure-healing or headache ? Results of a multicenter rnadomized placebo-controlled double-blind trial. Dis Colon Rectum 2000 43: 174\u201381.","DOI":"10.1007\/BF02236977"},{"key":"e_1_2_1_26_1","doi-asserted-by":"crossref","unstructured":"Bacher H. Mischinger H. J. Werkgartner G. Local nitroglyc-erin for treatment of anal fissure: An alternative to lateral sphinc-terotomy ?. Dis Colon Rectum 1997 40: 840\u20135.","DOI":"10.1007\/BF02055444"},{"key":"e_1_2_1_27_1","doi-asserted-by":"crossref","unstructured":"Carapeti E. A. Kamm M. A. McDonald P. J. Randomized controlled trial shows that glyceryl trinitrate heals anal fissures higher doses are not more effective and there is a high recurrence rate. Gut 1999 44: 727\u201330.","DOI":"10.1136\/gut.44.5.727"},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","unstructured":"Carapeti E. A. Kamm M. A. Evans B. K. Phillips R. K. S. Diltiazem lowers resting anal sphincter pressure: A potential low side-effect alternative to glyceryl trinitrate for fissures. Gut 1998 42: A97.","DOI":"10.1016\/S0016-5085(98)80026-7"},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","unstructured":"Cook T. A. Humphreys M. M. F. Mortensen N. J. M. Oral nifedipine reduces resting anal pressure and heals chronic anal fissure. Br J Surg 1999 86: 1269\u201373.","DOI":"10.1046\/j.1365-2168.1999.01292.x"},{"key":"e_1_2_1_30_1","doi-asserted-by":"crossref","unstructured":"Kocher H. M. Steward M. Leather A. J. M. Cullen P. T. Randomized clinical trial assessing the side-effect of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure. Br J Surg 2002 89: 413\u20137.","DOI":"10.1046\/j.0007-1323.2001.02042.x"},{"key":"e_1_2_1_31_1","doi-asserted-by":"crossref","unstructured":"Oettle G. J. Glycerly trinitrate vs. sphincterotomy for treatment of chronic fissure in-ano: a randomized controlled trial. Dis Colon Rectum 1997 40: 1318\u201320.","DOI":"10.1007\/BF02050816"}],"container-title":["Acta Chirurgica Belgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00015458.2006.11679834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T19:33:54Z","timestamp":1741894434000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00015458.2006.11679834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1080\/00015458.2006.11679834"],"URL":"https:\/\/doi.org\/10.1080\/00015458.2006.11679834","relation":{},"ISSN":["0001-5458","2577-0160"],"issn-type":[{"type":"print","value":"0001-5458"},{"type":"electronic","value":"2577-0160"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}