{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:18:11Z","timestamp":1789607891418,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":1582,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Background.<\/jats:italic>\n                    Few studies have examined smoking prior to pregnancy and the occurrence of spontaneous abortion, as most studies have addressed the risk of spontaneous abortion in relation to smoking during pregnancy. However, results are not entirely consistent. The aim of the present study was to assess the risk of spontaneous abortion considering smoking prior to pregnancy.\n                    <jats:italic>Methods.<\/jats:italic>\n                    We performed a nested case\u2013control study using prospective data from a population\u2010based cohort comprising 11,088 women aged 20\u201329 years. From this cohort, women who experienced either a spontaneous abortion (\n                    <jats:italic>n<\/jats:italic>\n                    =343) or who gave birth (\n                    <jats:italic>n<\/jats:italic>\n                    =1,578) during follow\u2010up were selected. Associations between self\u2010reported smoking at enrolment and subsequent spontaneous abortion were analyzed by means of multiple logistic regression.\n                    <jats:italic>Results.<\/jats:italic>\n                    The risk of spontaneous abortion in relation to pre\u2010pregnancy smoking showed a clear dose\u2013response effect. The adjusted odds ratio (95% confidence interval) for spontaneous abortion among current smokers prior to conception was 1.20 (1.04\u20131.39) per every extra five cigarettes smoked per day. The increased risk was only present for current smokers. The duration of smoking prior to pregnancy was not a significant predictor for subsequent spontaneous abortion.\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    The amount of daily smoking prior to pregnancy seems to be associated with an increased risk of spontaneous abortion, whereas the duration of smoking does not seem to be related to an increased risk of spontaneous abortion.\n                  <\/jats:p>","DOI":"10.1080\/00016340600589560","type":"journal-article","created":{"date-parts":[[2009,12,8]],"date-time":"2009-12-08T12:34:28Z","timestamp":1260275668000},"page":"1057-1065","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Maternal smoking predicts the risk of spontaneous abortion"],"prefix":"10.1111","volume":"85","author":[{"given":"Ann","family":"Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Gerd Hannibal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodil","family":"Eriksen Lindekilde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janne","family":"Tolstrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Frederiksen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Munk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bergholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisbeth","family":"Buss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bent","family":"Ottesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Gr\u00f8nbaek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Kr\u00fcger Kjaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2003.00078.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2003.00244.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.11.2426"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-842X.2000.tb01604.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199902043400501"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-2797(98)00017-9"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117444"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01719278"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.82.1.85"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116250"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(89)90023-3"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19960301)65:5<601::AID-IJC8>3.0.CO;2-6"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg480"},{"key":"e_1_2_6_15_2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1055\/s-0038-1635466","article-title":"Registration of diagnoses in the Danish National Registry of patients","volume":"25","author":"J\u00fcrgensen HJ","year":"1986","journal-title":"Methods Inf Med"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7251.1708"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1998.0377"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.11.024"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/5.2.125"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/140349489302100309"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/6.2.122"},{"key":"e_1_2_6_22_2","doi-asserted-by":"crossref","unstructured":"BussL TolstrupJ MunkC BergholtT OttesenB Gr\u00f8nb\u00e6kM et al.Spontaneous abortion \u2013 a prospective cohort study of younger women from the general population in Denmark. Validation occurrence and risk determinants.Acta Obstet Gynecol Scand2005(in press).","DOI":"10.1080\/00016340500494887"},{"key":"e_1_2_6_23_2","unstructured":"MunkC.Younger women and smoking: a longitudinal study of the trend in smoking prevalence and determinants of smoking initiation and cessation among nearly 14.000 Danish women. Ph.D. dissertation. Institute of Cancer Epidemiology Danish Cancer Society University of Copenhagen 2001."}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F00016340600589560","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/00016340600589560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T09:51:40Z","timestamp":1697017900000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1080\/00016340600589560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1080\/00016340600589560"],"URL":"https:\/\/doi.org\/10.1080\/00016340600589560","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}