{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T22:42:41Z","timestamp":1787784161391,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":1340,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>. Part of the success of ultrasound\u2010guided embryo transfer has been associated with the beneficial effect of uterine straightening by passive bladder distention. Even so, this has not been properly analysed in the literature. <jats:italic>Methods<\/jats:italic>. This is a systematic review and meta\u2010analysis of prospective, randomised, controlled trials, comparing embryo transfer with a full versus empty bladder. Electronic (e.g. PubMed, EMBASE, Cochrane Library) and hand searches were performed to locate trials. Primary outcomes were live\u2010birth, ongoing and clinical pregnancy rates. Secondary outcomes were rates of implantation, miscarriage, multiple and ectopic pregnancies, and retained embryos. Also, the ease of transfer, need for instrumental assistance, and presence of blood on the catheter tip were evaluated. Four studies were identified, of which 1 study was excluded. Meta\u2010analysis was conducted with the Mantel\u2013Haenszel method, utilising the fixed\u2010effect model. <jats:italic>Results<\/jats:italic>. For the primary outcome measures, no data was available for the LBR rate. There was a significantly higher chance of an ongoing pregnancy [OR = 1.44 (95% CI = 1.04\u20132.04)] and clinical pregnancy [OR = 1.55 (95% CI = 1.16\u20132.08)] with a full bladder. For the secondary outcomes, there was a significantly greater incidence of difficulty, or need for instrumental assistance, with an empty bladder. Other outcome measures were not significantly different. <jats:italic>Conclusion<\/jats:italic>. There is evidence in the literature advising to fill the bladder prior to embryo transfer.<\/jats:p>","DOI":"10.1080\/00016340701252126","type":"journal-article","created":{"date-parts":[[2007,7,25]],"date-time":"2007-07-25T03:45:43Z","timestamp":1185335143000},"page":"516-522","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Effect of passive uterine straightening during embryo transfer: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"86","author":[{"given":"AHMED M.","family":"ABOU\u2010SETTA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/10.suppl_2.60"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.5.1149"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.6.1540"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei198"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)60860-7"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)53829-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00315-X"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg359"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_6_11_2","unstructured":"Lorusso F Depalo R Bettocchi S Vacca M Vimereati A Selvaggi L.Outcome ofin vitrofertilization after transabdominal ultrasound\u2010assisted embryo transfer with a full or empty bladder.Research Papers in Fertility and Reproductive Medicine: Proceedings of the 18th World Congress on Fertility and Sterility (IFFS 2004);2004."},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01132876"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02765749"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.04.027"},{"key":"e_1_2_6_15_2","first-page":"998","article-title":"Impact of \u2018non\u2010physician factors\u2019 on the \u2018physician factor\u2019 of in vitro fertilization success: is it the broth, the cooks, or the statistics?","volume":"71","author":"Lu MC","year":"1999","journal-title":"Fertil Steril"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","unstructured":"Abou\u2010Setta AM Mansour RT Al\u2010Inany HG Aboulghar MM Serour GI Aboulghar MA.Among women undergoing embryo transfer is the probability of pregnancy and live birth improved with ultrasound\u2010guidance than with clinical touch alone? A systemic review and meta\u2010analysis of prospective randomized trials.Fertil Steril.2007(in press).","DOI":"10.1016\/j.fertnstert.2007.07.149"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a019470"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/14.3.677"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.8.2107"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)48854-0"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93094-P"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(03)01009-4"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.319.7204.220"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01228088"},{"key":"e_1_2_6_25_2","doi-asserted-by":"crossref","unstructured":"Al\u2010Inany HG Abou\u2010Setta AM Garzo G.ET catheters for assisted reproduction. 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