{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:32:34Z","timestamp":1787005954725,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":1309,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2007,6]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:italic>\n . Both misoprostol\u2010alone and a combination of mifepristone plus misoprostol have been used in induction of labor in cases of intrauterine fetal death (IUFD).\n Methods<\/jats:italic>\n . Data from 130 women with IUFD at 21\u201342 weeks of gestation were analysed retrospectively. A total of 82 women received 100 \u03bcg (median) of misoprostol at 4\u2010h intervals. Some 48 women received 200 mg of mifepristone, followed 19 h (median) later by single doses of 25 \u03bcg of misoprostol at 4\u2010h intervals.\n Results<\/jats:italic>\n . The induction\u2010to\u2010delivery time did not differ between the groups (13.3 versus 12.8 h). However, between 21 and 25 weeks of gestation, the induction\u2010to\u2010delivery time was shorter with the combination regimen (\n p<\/jats:italic>\n = 0.04). The total dose of misoprostol needed was lower in the group pre\u2010treated with mifepristone (\n p<\/jats:italic>\n = 0.0028). The 2 groups did not differ as regards complications experienced during labor and delivery.\n Conclusions<\/jats:italic>\n . Both regimens, misoprostol\u2010only and the combination of mifepristone and misoprostol, are effective and safe in induction of labor after IUFD. Pre\u2010treatment with mifepristone is more effective at earlier gestational weeks.\n <\/jats:p>","DOI":"10.1080\/00016340701379853","type":"journal-article","created":{"date-parts":[[2007,5,23]],"date-time":"2007-05-23T20:54:33Z","timestamp":1179953673000},"page":"701-705","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Misoprostol\u2010only versus mifepristone plus misoprostol in induction of labor following intrauterine fetal death"],"prefix":"10.1111","volume":"86","author":[{"given":"WILMA","family":"V\u00c4YRYNEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OSKARI","family":"HEIKINHEIMO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MIKA","family":"NUUTILA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-198706000-00011"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6934(03)00068-3"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90295-X"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/01443619609004091"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/01443619609030086"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200306000-00044"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.12.012"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2005.00338.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(95)02593-6"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01238.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2004.04.001"},{"key":"e_1_2_5_13_2","first-page":"266","article-title":"Pelvic scoring for elective induction","volume":"24","author":"Bishop EH","year":"1964","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)60522-6"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1988.tb06840.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(00)00506-6"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101043440107"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F00016340701379853","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/00016340701379853","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:45:55Z","timestamp":1697060755000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1080\/00016340701379853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1080\/00016340701379853"],"URL":"https:\/\/doi.org\/10.1080\/00016340701379853","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}