{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:05:24Z","timestamp":1791158724509,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":1095,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background.<\/jats:italic> Previous studies suggest that the occurrence of pre\u2010eclampsia is seasonally distributed. This retrospective study aims to determine whether there is a seasonal variation in the number of admissions and the prevalence of women with pre\u2010eclampsia in Tygerberg Hospital, South Africa. <jats:italic>Methods.<\/jats:italic> The number of women admitted with a diagnosis of pre\u2010eclampsia, eclampsia or haemolysis elevated liver enzymes low platelets (HELLP) syndrome (together called pre\u2010eclampsia) was obtained from hospital records from 2002 to 2003 for each season and month. Associations were analysed with Odds Ratios (OR). Furthermore, these data was compared with the Cape Town temperatures recorded on each day over the period, as well as the total rainfall for each month. Bivariate logistic regression of the probability of pre\u2010eclampsia on temperature and rainfall was performed. <jats:italic>Results.<\/jats:italic> Pre\u2010eclampsia occurred in 11.5% of all admissions (1,329\/11,585). The prevalence was highest in winter (13.6% pre\u2010eclampsia patients from all admissions). Women admitted in winter had a higher risk of developing pre\u2010eclampsia compared to those admitted in summer (OR =1.69, 95% CI: 1.07\u20131.53). The risk of developing pre\u2010eclampsia in June was higher than in February (summer in South Africa, reference month) (OR =2.81, 95% CI: 2.06\u20133.83). There was a significant correlation between the number of admissions with pre\u2010eclampsia and the minimum daily temperature (<jats:italic>r<\/jats:italic> = \u22120.620, <jats:italic>p<\/jats:italic> = 0.032). <jats:italic>Conclusions.<\/jats:italic> Pre\u2010eclampsia occurs more frequently in winter at Tygerberg Hospital, South Africa. The findings have implications for future research related to the aetiology of pre\u2010eclampsia as well as for clinical care.<\/jats:p>","DOI":"10.1080\/00016340701743066","type":"journal-article","created":{"date-parts":[[2007,12,21]],"date-time":"2007-12-21T21:39:17Z","timestamp":1198273157000},"page":"36-42","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Seasonal influence on the admittance of pre\u2010eclampsia patients in Tygerberg Hospital"],"prefix":"10.1111","volume":"87","author":[{"given":"ANNELIES","family":"IMMINK","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SICCO","family":"SCHERJON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RON","family":"WOLTERBEEK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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