{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:10:36Z","timestamp":1757700636254},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":1064,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>. Retrospective study of 744 women at the Virgen del Camino Hospital in Pamplona concerning two variants for the active treatment of premature rupture of the membranes (PROM). The main purpose of the study was to assess the differences between two variants for the active treatment of PROM at term in pregnant women with negative vaginal\u2010rectal culture screening for Group B Streptococci, and a Bishop test of 4 or less on admission. <jats:italic>Methods.<\/jats:italic> Retrospective study of 744 patients with single pregnancy at term, PROM, and Bishop test &lt;4. The patients, who were not randomised, were treated with dinoprostone (Propess\u00ae) or expectant therapy, according to the physician's choice. Induction with oxytocin was started 12 h after PROM. Qualitative data were analysed using the \u03c7<jats:sup>2<\/jats:sup> test, while quantitative data were analysed using the Student's <jats:italic>t<\/jats:italic>\u2010test or the Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test according to the distribution of the variables. Regression models were applied to correct the biases caused by confounding variables. <jats:italic>Results<\/jats:italic>. Of the 744 patients, the cervix of 13% was maturated with pericervical dinoprostone, while 87% were subject to expectant management until 12 h after rupture of the membranes. The time of dilation and the time until labour were significantly shorter in the dinoprostone group (<jats:italic>p<\/jats:italic> = 0.0). The rate of caesarean sections was also lower in the dinoprostone group at 9.3% compared to 17.6% in the expectant management group, reaching statistical significance (<jats:italic>p<\/jats:italic> = 0.04). There were no differences in the parameters of fetal well being (Apgar and pH). <jats:italic>Conclusions<\/jats:italic>. The use of therapy with dinoprostone in patients with PROM could be a safe method and more effective than expectant management.<\/jats:p>","DOI":"10.1080\/00016340701837421","type":"journal-article","created":{"date-parts":[[2008,1,29]],"date-time":"2008-01-29T12:56:50Z","timestamp":1201611410000},"page":"195-200","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Dinoprostone vaginal slow\u2010release system (Propess\u00ae) compared to expectant management in the active treatment of premature rupture of the membranes at term: impact on maternal and fetal outcomes"],"prefix":"10.1111","volume":"87","author":[{"given":"CARLOS","family":"LARRA\u00d1AGA\u2010AZC\u00c1RATE","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GEMA","family":"CAMPO\u2010MOLINA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANA","family":"FELICITAS P\u00c9REZ\u2010RODR\u00cdGUEZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MIGUEL","family":"EZCURDIA\u2010GURPEGUI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_8_2_2","unstructured":"Sociedad Espa\u00f1ola de Ginecolog\u00eda y Obstetricia (SEGO).Protocolos asistenciales en obstetricia. Rotura prematura de membranas No. 30. SEGO;2003."},{"issue":"1","key":"e_1_2_8_3_2","first-page":"89","article-title":"Prostaglandins in preinduction cervical ripening. Meta\u2010analysis of worldwide clinical experience","volume":"38","author":"Keirse M","year":"1993","journal-title":"J Reprod Med"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00039.x"},{"issue":"3","key":"e_1_2_8_5_2","first-page":"173","article-title":"Early induction of labor with PGE2\u2010intravaginal gel in premature rupture of membranes","volume":"28","author":"Sturlese E","year":"2001","journal-title":"Clin Exp Obstet Gynecol"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604183341601"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349109007914"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199712000-00013"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(95)80014-X"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1992.tb14466.x"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.11.1417"},{"key":"e_1_2_8_12_2","first-page":"607","article-title":"Apport de l'administration intracervicale de PGE2 dans les ruptures pr\u00e9matur\u00e9es des membranes \u00e1 terme","volume":"29","author":"Hidar S","year":"2000","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"e_1_2_8_13_2","first-page":"115","article-title":"A randomized trial of vaginal prostaglandin E2 for induction of labor. Insert vs. tablet","volume":"47","author":"Rabl M","year":"2002","journal-title":"J Reprod Med"},{"key":"e_1_2_8_14_2","volume-title":"Planned early birth versus expectant management (waiting) for pre\u2010labour rupture of membranes at term (37 weeks or more). The Cochrane Library; Issue 2","author":"Dare MR","year":"2006"},{"key":"e_1_2_8_15_2","volume-title":"Best practice in labor ward management","author":"Atalla R","year":"2000"},{"key":"e_1_2_8_16_2","volume-title":"Management of premature rupture of the foetal membranes at term","author":"Scorza WE","year":"2006"},{"key":"e_1_2_8_17_2","volume-title":"Estudio comparativo entre inducci\u00f3n de parto por RPM sin maduraci\u00f3n cervical frente a maduraci\u00f3n con PGE2","author":"Campo Molina G","year":"2005"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F00016340701837421","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/00016340701837421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T04:17:11Z","timestamp":1697429831000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1080\/00016340701837421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["10.1080\/00016340701837421"],"URL":"https:\/\/doi.org\/10.1080\/00016340701837421","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}