{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T16:26:51Z","timestamp":1770568011911,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":578,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>. To determine the incidence of isolated anencephaly and spina bifida in the Arkhangelskaja Oblast (AO) in Russia and in Norway, and to study the maternal age distribution of these congenital defects. <jats:italic>Design<\/jats:italic>. A register\u2010based incidence study. <jats:italic>Setting<\/jats:italic>. Two different populations in Northern Europe. <jats:italic>Population<\/jats:italic>. All registered fetuses and newborns with at least 12 weeks\u2019 gestation in the populations of AO (1995\u20132004) and Norway (1999\u20132003) were included. A total of 141,159 in AO and 293,708 in Norway. <jats:italic>Methods<\/jats:italic>. Data were obtained from the malformation register in AO and the Medical Birth Registry of Norway. <jats:italic>Main outcome measures<\/jats:italic>. Total and maternal age\u2010group specific incidence of anencephaly and spina bifida. <jats:italic>Results<\/jats:italic>. A total of 298 newborns and abortuses had one of the defects in AO (21.1\/10,000 (95% confidence interval:\u00b13.4)) and 317 (10.8\/10,000 (\u00b11.2)) in Norway. The incidence of anencephaly was 10.7\/10,000 in AO and 5.5 in Norway, and of spina bifida 10.4 and 5.3, respectively. An inverse association between the age of the pregnant women and the incidence of neural tube defects was observed in both populations; for both anencephaly and spina bifida in AO; but only for anencephaly (age &lt; 30 years) in Norway. <jats:italic>Conclusions<\/jats:italic>. The incidence of both anencephaly and spina bifida was higher in a northern population of Russia than in Norway. The burden of anencephaly was highest in the youngest maternal age group in both populations. The relatively high incidence of both anencephaly and spina bifida in the Russian population warrants further studies.<\/jats:p>","DOI":"10.1080\/00016340902898008","type":"journal-article","created":{"date-parts":[[2009,4,7]],"date-time":"2009-04-07T11:32:59Z","timestamp":1239103979000},"page":"667-672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The incidence of neural tube defects in Norway and the Arkhangelskaja Oblast in Russia and the association with maternal age"],"prefix":"10.1111","volume":"88","author":[{"given":"JELENA G.","family":"PETROVA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ARILD","family":"VAKTSKJOLD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpp.2000.112052"},{"key":"e_1_2_6_3_2","unstructured":"EUROCAT.European surveillance of congenital anomalies.2008. Available online at: http:\/\/www.eurocat.ulster.ac.uk\/. (accessed March 28 2009)."},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1784"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.44.s3.2.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050850"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.10.1223"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/0144361021000003636"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2000.00246.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420490210"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20065"},{"key":"e_1_2_6_12_2","first-page":"62","article-title":"Maternal age and neural tube defects: evidence for a greater effect in spina bifida than in anencephaly (in Spanish)","volume":"133","author":"Vieira AR","year":"2005","journal-title":"Rev Med Chil"},{"key":"e_1_2_6_13_2","volume-title":"Medmonitor statistical bulletin","year":"2008"},{"key":"e_1_2_6_14_2","first-page":"53","article-title":"Impact of prenatal diagnosis on the incidence of severe malformations in the Arkhangelsk Region according to monitoring data (in Russian)","volume":"4","author":"Petrova YG","year":"2005","journal-title":"Ros Vestn Perinatol Pediat"},{"key":"e_1_2_6_15_2","first-page":"117","article-title":"First supervision about trends in NTDs prevalence within Moscow region","volume":"17","author":"Zhuchenko L","year":"2003","journal-title":"Reprod Toxicol"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.3402\/ijch.v68i1.18297"},{"key":"e_1_2_6_17_2","first-page":"57","article-title":"Secular trends of neural tube defects by demographic subgroups in Norway, 1967\u201381","volume":"5","author":"Windham G","year":"1982","journal-title":"NIPH Annals"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.86.10.1454"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-5-82"},{"key":"e_1_2_6_20_2","volume-title":"Helse\u2010 og omsorgsdepartementet. Hefte 16, Medisinsk f\u00f8dselsregisterforskrift, kapittel 1. [Directive for the Medical Birth Register, chapter 1] (in Norwegian.)","year":"2001"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2004.00335.x"},{"key":"e_1_2_6_22_2","first-page":"13","article-title":"Monitoring of congenital malformation and its significance in the study of their epidemiology (in Russian)","volume":"4","author":"Demikova NS","year":"2003","journal-title":"Ros Vestn Perinatol Pediat"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.45.1.52"},{"key":"e_1_2_6_24_2","first-page":"465","article-title":"The epidemiology of neural tube defects in high\u2010prevalence and low\u2010prevalence areas of China (in Chinese. Only abstract available)","volume":"24","author":"Pei LJ","year":"2003","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121471"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601691"},{"key":"e_1_2_6_27_2","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1542\/peds.111.S1.1152","article-title":"Maternal obesity and risk for birth defects","volume":"111","author":"Watkins ML","year":"2003","journal-title":"Pediatrics"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03490070064043"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.54.1.17"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10257.x"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000152914.84962.13"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320320317"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.2307\/2533386"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F00016340902898008","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/00016340902898008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T02:52:52Z","timestamp":1697424772000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1080\/00016340902898008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1080\/00016340902898008"],"URL":"https:\/\/doi.org\/10.1080\/00016340902898008","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}