{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:09:29Z","timestamp":1771333769470,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":517,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>. To investigate the relation between changes in Doppler parameters of fetal and uterine arteries and development of persistent non\u2010reassuring fetal heart rate (FHR) pattern during induction of labor with dinoprostone (Propess\u00ae) in pregnancies at \u226541 weeks gestation. <jats:italic>Design<\/jats:italic>. Prospective cohort study. <jats:italic>Setting<\/jats:italic>. Etlik Zubeyde Hanim Women's Hospital, Turkey. <jats:italic>Sample.<\/jats:italic> One hundred forty\u2010one prolonged pregnancies. <jats:italic>Methods.<\/jats:italic> Doppler parameters of umbilical, middle cerebral, and uterine arteries were measured before and 4\u20136 hours after dinoprostone application between uterine contractions. Non\u2010reassuring FHR pattern and persistent non\u2010reassuring FHR pattern criteria were defined based on NICE 2007 guidelines. Women with successful spontaneous vaginal delivery were recruited as a control group (<jats:italic>n<\/jats:italic> = 108), while women who underwent cesarean delivery due to persistent non\u2010reassuring FHR pattern were recruited as a study group (<jats:italic>n<\/jats:italic> = 15). <jats:italic>Main outcome measures<\/jats:italic>. Prediction of non\u2010reassuring FHR pattern with Doppler analysis of uterine and fetal arteries. <jats:italic>Results<\/jats:italic>. After dinoprostone application there was significant enhancement in uterine artery resistance index (RI) in the study group compared to the control group (<jats:italic>p<\/jats:italic> = 0.002). Receiver operating characteristics curve analysis identified a uterine artery RI increase value of 0.11 as the optimal threshold for prediction of persistent non\u2010reassuring FHR pattern with 73.3% sensitivity and 69.4% specificity. Logistic regression analysis demonstrated that an increase in the uterine artery RI was predictive for persistent non\u2010reassuring FHR pattern (odds ratio (OR) 4.97; 95% CI 1.5\u201316.8). <jats:italic>Conclusion<\/jats:italic>. Acute increase in uterine artery RI due to dinoprostone use may end with persistent non\u2010reassuring FHR pattern in prolonged pregnancies. This may allow earlier prediction of persistent non\u2010reassuring FHR pattern development and risk assessment.<\/jats:p>","DOI":"10.1080\/00016340903100347","type":"journal-article","created":{"date-parts":[[2009,6,27]],"date-time":"2009-06-27T12:33:10Z","timestamp":1246105990000},"page":"894-900","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Is there any relation between development of persistent non\u2010reassuring fetal heart rate pattern and acutely increased uterine artery vascular flow resistance during dinoprostone use in prolonged pregnancies?"],"prefix":"10.1111","volume":"88","author":[{"given":"DENIZ","family":"KARCAALTINCABA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DERYA","family":"AKDAG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"OMER","family":"KANDEMIR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SERDAR","family":"YALVAC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EMINE SEDA GUVENDAG","family":"GUVEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALI","family":"HABERAL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016340500523685"},{"key":"e_1_2_6_3_2","first-page":"CD004945","article-title":"Induction of labour for improving birth outcomes for women at or beyond term","volume":"4","author":"Gulmezoglu AM","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016340701837421"},{"key":"e_1_2_6_5_2","volume-title":"International statistical classification of diseases and related health problems, 10th revision","author":"World Health Organization","year":"2006"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10047.x"},{"key":"e_1_2_6_7_2","unstructured":"Mary Hannah M andthe Maternal\u2010Fetal Medicine Committee of the Society of Obstetricians and Gynaecologists of Canada.Post\u2010term pregnancy. 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