{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T07:19:30Z","timestamp":1697095170886},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T00:00:00Z","timestamp":1293753600000},"content-version":"vor","delay-in-days":456,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objectives.<\/jats:italic> To determine the incidence of thyroid abnormality in pregnant women with hepatitis C virus (HCV) infection and evaluate pregnancy outcomes with respect to thyroid function status. <jats:italic>Design.<\/jats:italic> Prospective cohort study. <jats:italic>Setting.<\/jats:italic> Tertiary care hospital. <jats:italic>Population.<\/jats:italic> Pregnant women with HCV infection. <jats:italic>Methods.<\/jats:italic> Seventy\u2010eight HCV positive women had radioimmunoassay thyroid function tests. All were followed until delivery. Pregnancy outcomes were compared in women with and without subclinical hypothyroidism. <jats:italic>Main outcome measures.<\/jats:italic> Maternal and perinatal outcomes. <jats:italic>Results.<\/jats:italic> Of 78 anti\u2010HCV antibody positive pregnant women, 13 (16.7%) had abnormal thyroid\u2010stimulating hormone (TSH) (&gt;5 mIU\/L; hypothyroid group) and the remaining 65 (83.3%) had normal TSH values (euthyroid group). None had abnormal free T4 levels. None showed evidence of fetal distress in labor or fetal asphyxia. In the hypothyroid group, 23% compared to 6.2% in euthyroid group underwent cesarean section (<jats:italic>p<\/jats:italic> = 0.07). The incidence of preterm delivery (7.7% vs. 24.6%; <jats:italic>p<\/jats:italic> = 0.28), mean gestation at delivery (38.2\u00b11.8 vs. 37.5\u00b11.8 weeks, <jats:italic>p<\/jats:italic> = 0.19), and birthweight (2,687\u00b1430 g vs. 2,846\u00b1379 g, <jats:italic>p<\/jats:italic> = 0.18) was comparable. Neonatal nursery admissions were comparable. <jats:italic>Conclusion.<\/jats:italic> The presence of subclinical hypothyroidism in pregnant women with HCV infection does not adversely affect short\u2010term pregnancy outcomes.<\/jats:p>","DOI":"10.1080\/00016340903144220","type":"journal-article","created":{"date-parts":[[2009,7,27]],"date-time":"2009-07-27T18:56:30Z","timestamp":1248720990000},"page":"1133-1137","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Obstetric outcome in women with hepatitis C virus infection and thyroid dysfunction"],"prefix":"10.1111","volume":"88","author":[{"given":"ASHOK","family":"KUMAR","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KRISHNA","family":"AGARWAL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RAM KUMAR","family":"GUPTA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PREMASHISH","family":"KAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199903000-00017"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.171.195"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-11-881"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510310328"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2004.09.010"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.01.023"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0248-8663(00)88683-X"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(05)00018-2"},{"key":"e_1_2_6_10_2","first-page":"252","article-title":"Thyroid function in pregnancy","volume":"57","author":"Kumar A","year":"2003","journal-title":"Ind J Med Sci."},{"key":"e_1_2_6_11_2","first-page":"1189","volume-title":"Williams obstetrics","author":"Cunningham FG","year":"2005"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1996.tb09736.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2002.810202.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.4.526"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.13.1445"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840200650"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1320587"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(05)80022-4"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1997.00440310023002"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.2.228"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1089\/105072503321086962"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000152345.99421.22"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908193410801"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00639.x"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00686.x"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00790.x"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F00016340903144220","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/00016340903144220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T20:47:02Z","timestamp":1697057222000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1080\/00016340903144220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["10.1080\/00016340903144220"],"URL":"https:\/\/doi.org\/10.1080\/00016340903144220","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"2010-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}