{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T13:06:16Z","timestamp":1779800776062,"version":"3.53.1"},"reference-count":30,"publisher":"Informa UK Limited","issue":"5","funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFC2511100\/2024YFC2511105"],"award-info":[{"award-number":["2024YFC2511100\/2024YFC2511105"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Committee of Science and Technology","award":["21Y31900504"],"award-info":[{"award-number":["21Y31900504"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Acta Oto-Laryngologica"],"published-print":{"date-parts":[[2026,5,4]]},"DOI":"10.1080\/00016489.2026.2621930","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T13:55:14Z","timestamp":1772718914000},"page":"633-644","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Comparative efficacy of tympanostomy tube insertion for secretory otitis media following radiotherapy for head and neck malignancies: a network meta-analysis"],"prefix":"10.1080","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4071-0320","authenticated-orcid":false,"given":"Jingyi","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Ear Institute, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jifang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Ear Institute, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sihan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Ear Institute, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengjie","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Ear Institute, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoli","family":"Duan","sequence":"additional","affiliation":[{"name":"Ear Nose and Throat Patient Area, Trauma and Reparative Medicine Theme, Karolinska University Hospital","place":["Stockholm, Sweden"]},{"name":"Division of Ear, Nose and Throat Diseases, Department of Clinical Science, Intervention and Technology, Karolinska Institutet","place":["Stockholm, Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]},{"name":"Ear Institute, Shanghai Jiao Tong University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,3,4]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198711000-00008"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31818208d6"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489850155026"},{"issue":"9","key":"e_1_3_2_5_1","first-page":"1345","article-title":"Outcomes of hearing in nasopharyngeal carcinoma patients with secretory otitis media before and after radiotherapy","volume":"31","author":"Qiu GG","year":"2010","unstructured":"Qiu GG, He R, Chen YG, et al. Outcomes of hearing in nasopharyngeal carcinoma patients with secretory otitis media before and after radiotherapy. Sichuan Med J. 2010;31(9):1345\u20131346.","journal-title":"Sichuan Med J"},{"key":"e_1_3_2_6_1","unstructured":"Tang ZH Chen RH. Radiation-induced ear injury. Chin J of Otorhinolaryngol Head Neck Surg. 2012 Feb; 47(2):92-6. Chinese."},{"key":"e_1_3_2_7_1","unstructured":"Kew J Fau KA Leung SF et al. Middle ear effusions after radiotherapy: correlation with pre-radiotherapy nasopharyngeal tumor patterns. Am J Otol. 2000 Nov;21(6):782\u20135."},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2004.11.002"},{"key":"e_1_3_2_9_1","first-page":"163","article-title":"Clinical efficacy of tympanic tube insertion for the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Mai PQ","unstructured":"Mai PQ, Chen XY. Clinical efficacy of tympanic tube insertion for the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Guide Chin Med. 2012,10(5):163\u2013164.","journal-title":"Guide Chin Med"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111001002"},{"key":"e_1_3_2_11_1","first-page":"146","article-title":"Comparative analysis of the efficacy of CO2 laser tympanostomy and tube insertion in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Wang ZQ","unstructured":"Wang ZQ, Yan XD, Zhang XY. Comparative analysis of the efficacy of CO2 laser tympanostomy and tube insertion in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Psychol Doc. 2017,23(6):146\u2013148.","journal-title":"Psychol Doc"},{"key":"e_1_3_2_12_1","first-page":"45","article-title":"Comparison of the efficacy of CO2 laser tympanostomy and tube insertion in the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Ling QM","unstructured":"Ling QM, Fang C, Wang JF. Comparison of the efficacy of CO2 laser tympanostomy and tube insertion in the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Fujian Med J. 2019,41(2):45\u201348.","journal-title":"Fujian Med J"},{"issue":"1","key":"e_1_3_2_13_1","first-page":"37","article-title":"A comparative research of CO2 laser tympanostomy and Grommet insertion in the treatment of nasopharyngeal carcinoma after radiotherapy with otitis media with effusion","volume":"25","author":"Xu ZJ","year":"2017","unstructured":"Xu ZJ, Luo HZ, Zhong XY, et al. A comparative research of CO2 laser tympanostomy and Grommet insertion in the treatment of nasopharyngeal carcinoma after radiotherapy with otitis media with effusion. Chin J Otorhinolarngol Integ Med. 2017;25(1):37\u201340.","journal-title":"Chin J Otorhinolarngol Integ Med"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.01.042"},{"issue":"24","key":"e_1_3_2_15_1","first-page":"387","article-title":"Discussion on the treatment of secretory otitis media after radiotherapy of nasopharyngeal carcinoma","volume":"2013","author":"Xu HF","unstructured":"Xu HF, Xu W, Liao JY, et al. Discussion on the treatment of secretory otitis media after radiotherapy of nasopharyngeal carcinoma. Front Med. 2013(24):387-388.","journal-title":"Front Med"},{"issue":"10","key":"e_1_3_2_16_1","first-page":"1357","article-title":"Comparison of the efficacy of laser tympanostomy and tube insertion for the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma","volume":"28","author":"Chen M","year":"2015","unstructured":"Chen M, Xu JH. Comparison of the efficacy of laser tympanostomy and tube insertion for the treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin J Clin Res. 2015;28(10):1357\u20131359.","journal-title":"Chin J Clin Res"},{"issue":"01","key":"e_1_3_2_17_1","first-page":"42","article-title":"CO2 laser tympanostomy therapy for secretory otitis media after radiotherapy for nasopharyngeal carcinoma","volume":"21","author":"Guo MK.","year":"2015","unstructured":"Guo MK. CO2 laser tympanostomy therapy for secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin Med Device Inf. 2015;21(01Z):42.","journal-title":"Chin Med Device Inf"},{"key":"e_1_3_2_18_1","first-page":"227","article-title":"Analysis of the efficacy of tube insertion and intratympanic injection in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Huang RK","unstructured":"Huang RK, Xiong QB, Huang JH, et al. Analysis of the efficacy of tube insertion and intratympanic injection in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin J Clin Oncol Rehabil. 2015,22(2):227\u2013229.","journal-title":"Chin J Clin Oncol Rehabil"},{"issue":"27","key":"e_1_3_2_19_1","first-page":"233","article-title":"Comprehensive treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma","volume":"2015","author":"Peng J.","unstructured":"Peng J. Comprehensive treatment of secretory otitis media after radiotherapy for nasopharyngeal carcinoma. J Med Inf. 2015(27):233-233.","journal-title":"J Med Inf"},{"key":"e_1_3_2_20_1","first-page":"1141","article-title":"Comparison of the efficacy of the tube insertion and the tympanocentesis in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Chen H.","unstructured":"Chen H. Comparison of the efficacy of the tube insertion and the tympanocentesis in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Anhui Med J. 2016,37(9):1141\u20131142.","journal-title":"Anhui Med J"},{"issue":"24","key":"e_1_3_2_21_1","first-page":"119","article-title":"Efficacy of endoscopic tympanocentesis and tympanic tube insertion in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","volume":"30","author":"Wang XM.","year":"2017","unstructured":"Wang XM. Efficacy of endoscopic tympanocentesis and tympanic tube insertion in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin J Med Device. 2017;30(24):119\u2013120.","journal-title":"Chin J Med Device"},{"key":"e_1_3_2_22_1","first-page":"37","article-title":"Clinical observation of endoscopic tympanocentesis and tympanic tube insertion plus ambroxol hydrochloride injection cleaning the middle ear cavity in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Zhu ZP.","year":"2017","unstructured":"Zhu ZP. Clinical observation of endoscopic tympanocentesis and tympanic tube insertion plus ambroxol hydrochloride injection cleaning the middle ear cavity in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Diet Health J. 2017,4(1):37\u201338.","journal-title":"Diet Health J"},{"issue":"43","key":"e_1_3_2_23_1","first-page":"5","article-title":"A comparative study of tympanic membrane catheterization and tympanic membrane puncture for secretory otitis media after radiotherapy for nasopharyngeal carcinoma","volume":"6","author":"Wen RH","year":"2019","unstructured":"Wen RH, Li XB. A comparative study of tympanic membrane catheterization and tympanic membrane puncture for secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Electron J Clin Med Lit. 2019;6(43):5\u20136.","journal-title":"Electron J Clin Med Lit"},{"key":"e_1_3_2_24_1","article-title":"Effectiveness and safety analysis of tube insertion therapy in secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Zhang X.","year":"2019","unstructured":"Zhang GX. Effectiveness and safety analysis of tube insertion therapy in secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin Health Care Nutr. 2019,29(24):96.","journal-title":"Chin Health Care Nutr"},{"issue":"12","key":"e_1_3_2_25_1","first-page":"100","article-title":"Study on treatment of secretory otitis media after radiotherapy of nasopharyngeal carcinoma with tympanic membrane catheter","volume":"11","author":"Zhang X.","year":"2019","unstructured":"Zhang X. Study on treatment of secretory otitis media after radiotherapy of nasopharyngeal carcinoma with tympanic membrane catheter. Chin Contin Med Educ. 2019;11(12):100\u2013103.","journal-title":"Chin Contin Med Educ"},{"key":"e_1_3_2_26_1","article-title":"Clinical therapeutic effects of tube insertion in treating patients with secretory otitis media after radiotherapy for nasopharyngeal carcinoma","author":"Cui XY","year":"2020","unstructured":"Cui XY, Song HY. Clinical therapeutic effects of tube insertion in treating patients with secretory otitis media after radiotherapy for nasopharyngeal carcinoma. Chin Health Care Nutr. 2020,30(18):105.","journal-title":"Chin Health Care Nutr"},{"issue":"4","key":"e_1_3_2_27_1","first-page":"59","article-title":"The efficacy of tube insertion in treating patients with secretory otitis media after radiotherapy for nasopharyngeal carcinoma: a review of 26 cases","volume":"38","author":"Yang X","year":"2008","unstructured":"Yang X, Yang X. The efficacy of tube insertion in treating patients with secretory otitis media after radiotherapy for nasopharyngeal carcinoma: a review of 26 cases. Xinjiang Med J. 2008;38(4):59\u201360.","journal-title":"Xinjiang Med J"},{"issue":"4","key":"e_1_3_2_28_1","first-page":"37","article-title":"Effects of CO2 laser tympanostomy on secretory otitis media after radiotherapy of nasopharyngeal carcinoma","volume":"38","author":"Zhong XY","year":"2018","unstructured":"Zhong XY, Xu ZZ, Luo HZ, et al. Effects of CO2 laser tympanostomy on secretory otitis media after radiotherapy of nasopharyngeal carcinoma. Clin Med. 2018;38(4):37\u201339.","journal-title":"Clin Med"},{"key":"e_1_3_2_29_1","first-page":"3462","article-title":"Endoscopic tube insertion in treatment of secretory otitis media after following radiotherapy for nasopharyngeal carcinoma","author":"Yuan ZL","year":"2014","unstructured":"Yuan ZL, Chen XZ, Fang JL. Endoscopic tube insertion in treatment of secretory otitis media after following radiotherapy for nasopharyngeal carcinoma. Jilin Med J. 2014,35(16):3462\u20133464.","journal-title":"Jilin Med J"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-010-1381-1"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31819d34ab"}],"container-title":["Acta Oto-Laryngologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00016489.2026.2621930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T12:38:24Z","timestamp":1779799104000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00016489.2026.2621930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,4]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5,4]]}},"alternative-id":["10.1080\/00016489.2026.2621930"],"URL":"https:\/\/doi.org\/10.1080\/00016489.2026.2621930","relation":{},"ISSN":["0001-6489","1651-2251"],"issn-type":[{"value":"0001-6489","type":"print"},{"value":"1651-2251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ioto20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ioto20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-23","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}