{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:37:28Z","timestamp":1793140648149,"version":"4.5.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aust N Z J Psychiatry"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:p>Objective: Oxcarbazepine was compared to divalproex to assess clinical effectiveness of a proven agent, divalproex, against a newer, less studied agent, oxcarbazepine, in the treatment of hypomania.<\/jats:p>\n                  <jats:p>Method: Thirty patients with bipolar disorder, currently hypomanic, were randomized to receive oxcarbazepine or divalproex as add-on or monotherapy for 8 weeks. A rater blind to treatment assignment performed all symptom ratings. Hypomania and depression were rated using the Young Mania Rating Scale (YMRS) and the Inventory of Depressive Symptoms\u2013Clinician Version (IDS-C). Random regression models were used to assess clinical symptom scores.<\/jats:p>\n                  <jats:p>Results: There were no significant differences of YMRS or IDS-C scores between groups. Mean YMRS scores at baseline were 22.07\u00b15.86 and 20.53\u00b16.02 for the oxcarbazepine and the divalproex groups, respectively. Mean percent reduction from baseline to week 8 for the YMRS was 63.8% and 79.0% for oxcarbazepine and divalproex groups, respectively. Mean percent reduction from baseline to week 8 for the IDS-C was 48.7% versus 19.7% for oxcarbazepine and divalproex groups, respectively. Significant antimanic efficacy was noted for each medication. Both medications were generally well tolerated.<\/jats:p>\n                  <jats:p>Conclusion: In this pilot study, oxcarbazepine was as effective as divalproex in the treatment of hypomania. Further controlled trials are warranted.<\/jats:p>","DOI":"10.1080\/00048670701261186","type":"journal-article","created":{"date-parts":[[2007,5,24]],"date-time":"2007-05-24T14:07:00Z","timestamp":1180015620000},"page":"397-402","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of Two Anticonvulsants in a Randomized, Single-Blind Treatment of Hypomanic Symptoms in Patients with Bipolar Disorder"],"prefix":"10.1177","volume":"41","author":[{"given":"Trisha","family":"Suppes","sequence":"first","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy I.","family":"Kelly","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda S.","family":"Hynan","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane E.","family":"Snow","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Sureddi","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Foster","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Curley","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2007,5,1]]},"reference":[{"key":"bibr1-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820140007001"},{"key":"bibr2-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.6.593"},{"key":"bibr3-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.10.1089"},{"key":"bibr4-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00338-5"},{"issue":"10","key":"bibr5-00048670701261186","first-page":"28","volume":"65","author":"Yatham LN","year":"2004","journal-title":"J Clin Psychiatry"},{"key":"bibr6-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-5618.2003.00047.x"},{"key":"bibr7-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00407-X"},{"key":"bibr8-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2005.00253.x"},{"key":"bibr9-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000195911.13870.f3"},{"key":"bibr10-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.2006.163.7.1179"},{"key":"bibr11-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03510360044034"},{"key":"bibr12-00048670701261186","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v61n1106"},{"key":"bibr13-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145703003754"},{"key":"bibr14-00048670701261186","volume-title":"Structured clinical interview for DSM-IV axis I disorders-clinician version (SCID-CV)","author":"First MB","year":"1997"},{"key":"bibr15-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.133.5.429"},{"key":"bibr16-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01866-8"},{"key":"bibr17-00048670701261186","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(97)00123-6"}],"container-title":["Australian &amp; 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