{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T13:17:27Z","timestamp":1761311847513},"reference-count":106,"publisher":"Informa UK Limited","issue":"9","funder":[{"name":"College of Heath Science, University of Kwazulu-Natal"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Neuroscience"],"published-print":{"date-parts":[[2023,9,2]]},"DOI":"10.1080\/00207454.2021.2019033","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T08:32:17Z","timestamp":1640248337000},"page":"959-976","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["Alteration of the \u03b15 GABA receptor and 5HTT lead to cognitive deficits associated with major depressive-like behaviors in a 14-day combined stress rat model"],"prefix":"10.1080","volume":"133","author":[{"given":"Gwladys Temkou","family":"Ngoupaye","sequence":"first","affiliation":[{"name":"Discipline of Human Physiology, School of Laboratory Medicine & Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"},{"name":"Department of Animal Biology, Faculty of Science, University of Dschang, Dschang, Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makwena","family":"Mokgokong","sequence":"additional","affiliation":[{"name":"Discipline of Human Physiology, School of Laboratory Medicine & Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thobeka","family":"Madlala","sequence":"additional","affiliation":[{"name":"Discipline of Human Physiology, School of Laboratory Medicine & Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musa Vuyisile","family":"Mabandla","sequence":"additional","affiliation":[{"name":"Discipline of Human Physiology, School of Laboratory Medicine & Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,1,2]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.65"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurpra.2018.03.006"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1002\/j.2051-5545.2011.tb00014.x"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169575"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1038\/475027a"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60602-8"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09298"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2014.05.013"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-015-2044-6"},{"key":"CIT0010","unstructured":"World Health Organization. 2018. Depression. Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/depression."},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-011-9171-0"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1159\/000492620"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.2009.01971.x"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.08.080"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.183.6.514"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.2165\/11539970-000000000-00000"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03590.x"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.122.5.509"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2015.04.004"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2018.01.005"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-013-3389-x"},{"issue":"8","key":"CIT0022","first-page":"199","volume":"6","author":"Albert PR","year":"2014","journal-title":"Front Behav Neurosci"},{"issue":"7","key":"CIT0023","first-page":"24","volume":"7","author":"Bravo JA","year":"2014","journal-title":"Front Mol Neurosci"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2015.12.039"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2009.00530.x"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-809825-7.00002-X"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.7.613"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-008-1428-9"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.9736.1"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1126\/science.1071829"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0581-2"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1159\/000409889"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.1.24"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(03)00269-7"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00162"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1771"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110603"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2010.03.007"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1038\/nature10287"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2015.12.005"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.03.082"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2013.09.017"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1002\/da.22262"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a021303"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2014.00003"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2015.112"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.12.038"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.06.023"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-017-0148-4"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01405-1"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2009.04.014"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2007.12.005"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-160662"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2015.11.006"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2005.04277.x"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2013.04.012"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2272012051"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.04.038"},{"issue":"97","key":"CIT0059","first-page":"52587","volume":"2015","author":"Yankelevitch-Yahav R","year":"2015","journal-title":"J Visual Exp"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1007\/BF00187257"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2017.05.021"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.04.061"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0270(84)90007-4"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1017\/neu.2016.22"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00063"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(01)00067-4"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2014.10.025"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1038\/srep14562"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2017.04.004"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2017.05.014"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.03.004"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2014.07.005"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-44462007000500004"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579414001059"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12379"},{"key":"CIT0076","doi-asserted-by":"crossref","unstructured":"Owens SA, Helms SW, Rudolph KD, et\u00a0al. 2018. Interpersonal stress severity longitudinally predicts adolescent girls\u2019 depressive symptoms: the moderating role of subjective and HPA axis stress responses. J Abnorm Child Psychol. 2019;47(5):895\u2013905.","DOI":"10.1007\/s10802-018-0483-x"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000572"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-12-05329.2003"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2006.02.008"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(01)01371-3"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-1883-x"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.11.009"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.3109\/15622970209150614"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agv090"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.09.010"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1002\/neu.1079"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1002\/neu.20025"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2008.12.004"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.116"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2016.08.007"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2009.03.002"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.04.008"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-014-0306-7"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1126\/science.290.5500.2315"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.11.2061"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhj114"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1598-05.2005"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhl108"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901720104"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2015.11.008"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1126\/science.1139560"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2640-12.2012"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2015.02.010"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2008.07.001"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078238"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00545"}],"container-title":["International Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00207454.2021.2019033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T23:32:40Z","timestamp":1691537560000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00207454.2021.2019033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,2]]},"references-count":106,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9,2]]}},"alternative-id":["10.1080\/00207454.2021.2019033"],"URL":"https:\/\/doi.org\/10.1080\/00207454.2021.2019033","relation":{},"ISSN":["0020-7454","1543-5245"],"issn-type":[{"value":"0020-7454","type":"print"},{"value":"1543-5245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ines20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ines20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-08-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-13","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}