{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T01:17:07Z","timestamp":1776475027511,"version":"3.51.2"},"reference-count":44,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology"],"published-print":{"date-parts":[[2001]]},"DOI":"10.1080\/00313020120038728","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:48:36Z","timestamp":1027698516000},"page":"142-148","source":"Crossref","is-referenced-by-count":21,"title":["Synovial sarcoma and malignant mesothelioma of the pleura: review, differential diagnosis and possible role of apoptosis"],"prefix":"10.1016","volume":"33","author":[{"given":"Francesco","family":"Cappello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon","family":"Barnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1080\/00313020120038728_bib0005","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/1097-0142(196505)18:5<613::AID-CNCR2820180510>3.0.CO;2-V","article-title":"Synovial sarcoma: An analysis of 134 tumors","volume":"18","author":"Cadman","year":"1965","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0010","first-page":"23","article-title":"Synovial sarcoma: a clin-icopathologic and ultrastructural study of 42 cases","volume":"33","author":"Tsuneyoshi","year":"1983","journal-title":"Acta Pathol Jpn"},{"key":"10.1080\/00313020120038728_bib0015","series-title":"Soft Tissue Tumors","first-page":"757","year":"1995"},{"key":"10.1080\/00313020120038728_bib0020","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/1097-0142(19820715)50:2<269::AID-CNCR2820500217>3.0.CO;2-7","article-title":"Orofacial synovial sarcoma. A clinicopathologic study of 11 new cases and review of the literature","volume":"50","author":"Shmookler","year":"1982","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0025","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1001\/archotol.1985.00800060095016","article-title":"Synovial sarcoma of the tongue base. The seventh reported case","volume":"111","author":"Holtz","year":"1985","journal-title":"Arch Otolaryngol"},{"key":"10.1080\/00313020120038728_bib0030","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/1097-0142(19930715)72:2<469::AID-CNCR2820720224>3.0.CO;2-Q","article-title":"Synovial sarcoma of the abdominal wall","volume":"72","author":"Fetsch","year":"1993","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0035","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/00000478-199601000-00004","article-title":"Biphasic synovial sarcoma arising in the pleural cavity. A clinicopathologic study of five cases","volume":"20","author":"Gaertner","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0040","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/S0954-6111(97)90093-7","article-title":"Primary biphasic synovial sarcoma of the pleura","volume":"91","author":"Jawahar","year":"1997","journal-title":"Respir Med"},{"key":"10.1080\/00313020120038728_bib0045","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1046\/j.1365-2559.1998.00565.x","article-title":"Synovial sarcoma of the pleura and its differentiation from other primary pleural tumours: a clinicopathological and immunohistochemical review of three cases","volume":"33","author":"Nicholson","year":"1998","journal-title":"Histopathology"},{"key":"10.1080\/00313020120038728_bib0050","series-title":"Soft Tissue Tumors","first-page":"787","year":"1995"},{"key":"10.1080\/00313020120038728_bib0055","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1046\/j.1365-2559.1997.5460776.x","article-title":"Pathology of malignant mesothelioma","volume":"30","author":"Attanoos","year":"1997","journal-title":"Histopathology"},{"key":"10.1080\/00313020120038728_bib0060","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/00000478-198906000-00005","article-title":"A biphasic tumor of the mediastinum with features of synovial sarcoma. A report of four cases","volume":"13","author":"Witkin","year":"1989","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0065","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/0046-8177(95)90242-2","article-title":"Primary pulmonary sarcomas with features of monophasic synovial sarcoma. A clinicopathological, immunohistochemical, and ultrastructural study of 25 cases","volume":"26","author":"Zeren","year":"1995","journal-title":"Hum Pathol"},{"key":"10.1080\/00313020120038728_bib0070","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1002\/1097-0142(19870515)59:10<1810::AID-CNCR2820591021>3.0.CO;2-R","article-title":"Histologic features relating to prognosis in synovial sarcoma","volume":"26","author":"Cagle","year":"1987","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0075","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/1097-0142(19920715)70:2<484::AID-CNCR2820700217>3.0.CO;2-7","article-title":"Tendosynovial sarcoma. Clinicopathologic features, treatment and prognosis","volume":"70","author":"Brodsky","year":"1992","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0080","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00000478-199301000-00004","article-title":"Survival in synovial sarcoma. A multivariate study of prognostic factors with special emphasis on the comparison between early death and long-term survival","volume":"17","author":"Oda","year":"1993","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0085","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1002\/(SICI)1097-0142(19990615)85:12<2596::AID-CNCR16>3.0.CO;2-K","article-title":"Synovial sarcoma. Identification of low and high risk groups","volume":"85","author":"Beigh","year":"1999","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0090","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1002\/1097-0142(19931001)72:7<2161::AID-CNCR2820720716>3.0.CO;2-2","article-title":"Synovial sarcoma. A study of intensive chemotherapy in 14 patients with localized disease","volume":"72","author":"Kampe","year":"1993","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0095","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1002\/1097-0142(19940515)73:10<2506::AID-CNCR2820731009>3.0.CO;2-S","article-title":"Synovial sarcoma. Uniform response of metastases to high dose ifosfamide","volume":"73","author":"Rosen","year":"1994","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0100","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1002\/1097-0142(19861001)58:7<1540::AID-CNCR2820580727>3.0.CO;2-5","article-title":"Diffuse malignant mesothe-lioma of pleura. Diagnosis and survival in 92 cases","volume":"58","author":"Adams","year":"1986","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0105","first-page":"64","article-title":"Malignant mesothelioma: diagnostic and management strategies for 1992","volume":"19","author":"Vogelzang","year":"1992","journal-title":"Semin Oncol"},{"key":"10.1080\/00313020120038728_bib0110","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1097\/00000478-199810000-00006","article-title":"Value of cytokeratin 5\/6 immunostaining in distinguishing epithelial mesothelioma of the pleura from lung adenocarcinoma","volume":"22","author":"Ordonez","year":"1998","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0115","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/00000478-199108000-00008","article-title":"Ber-EP4 antibody as a discriminant in the differential diagnosis of malignant mesothelioma versus adenocarcinoma","volume":"15","author":"Sheibani","year":"1991","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0120","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1097\/00000478-199206000-00007","article-title":"Immunoreactivity for BER-EP4 in adenocarcinomas, adenomatoid tumors, and malignant meso-theliomas","volume":"18","author":"Gaffey","year":"1992","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0125","first-page":"889","article-title":"Immunocytochemical differential diagnosis of diffuse pleural mesotheliomas: a clinicopatho-logical study of 158 cases","volume":"11","author":"Vortmeyer","year":"1991","journal-title":"Anticancer Res"},{"key":"10.1080\/00313020120038728_bib0130","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/ajcp\/112.1.75","article-title":"Role of immunohistochemistry in differentiating epithelial mesothelioma from adenocarcinoma. Review and update","volume":"112","author":"Ordonez","year":"1991","journal-title":"Am J Clin Pathol"},{"key":"10.1080\/00313020120038728_bib0135","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0968-0004(91)90041-S","article-title":"Intracellular calcium-binding proteins: more sites than insights","volume":"16","author":"Heizmann","year":"1991","journal-title":"Trends Biochem Sci"},{"key":"10.1080\/00313020120038728_bib0140","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/00000478-199609000-00001","article-title":"Calretinin: a novel immunocytochemical marker for mesothelioma","volume":"20","author":"Doglioni","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0145","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1136\/jcp.43.3.213","article-title":"Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelia","volume":"43","author":"Latza","year":"1990","journal-title":"J Clin Pathol"},{"key":"10.1080\/00313020120038728_bib0150","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/ajcp\/109.1.85","article-title":"Value of the Ber-EP4 antibody in differentiating epithelial pleural mesothelioma from adenocarcinoma. The M.D. Anderson experience and a critical review of the literature","volume":"109","author":"Ordonez","year":"1998","journal-title":"Am J Clin Pathol"},{"key":"10.1080\/00313020120038728_bib0155","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/BF00195777","article-title":"Immunoreactivity for bcl-2 protein in malignant mesothelioma and non-neoplastic mesothelium","volume":"424","author":"Segers","year":"1994","journal-title":"Virchows Arch"},{"key":"10.1080\/00313020120038728_bib0160","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0046-8177(96)90284-1","article-title":"Over-expression of bcl-2 protein in synovial sarcoma: A comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization","volume":"27","author":"Hirakowa","year":"1996","journal-title":"Hum Pathol"},{"key":"10.1080\/00313020120038728_bib0165","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000227695","article-title":"Immunohistochemical detection of bcl-2 and p53 proteins and apoptosis in soft tissue sarcoma: their correlations with prognosis","volume":"54","author":"Nakanishi","year":"1997","journal-title":"Oncology"},{"key":"10.1080\/00313020120038728_bib0170","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/(SICI)1096-9896(199704)181:4<362::AID-PATH764>3.0.CO;2-Y","article-title":"Bcl-2 expression in pleural and extrapleural solitary fibrous tumors","volume":"181","author":"Chilosi","year":"1997","journal-title":"J Pathol"},{"key":"10.1080\/00313020120038728_bib0175","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1097\/00000478-199807000-00008","article-title":"Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces and gastrointestinal tract","volume":"22","author":"Suster","year":"1998","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0180","first-page":"357","article-title":"Chromosomes in the diagnosis of soft tissue tumors. 1. Synovial sarcoma","volume":"5","author":"Dal Cin","year":"1992","journal-title":"Mod Pathol"},{"key":"10.1080\/00313020120038728_bib0185","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/(SICI)1097-0142(19970625)81:3<187::AID-CNCR9>3.0.CO;2-O","article-title":"Cytogenetics as an adjunct in establishing a definitive diagnosis of synovial sarcoma by fine-needle aspiration","volume":"81","author":"Saboorian","year":"1997","journal-title":"Cancer"},{"key":"10.1080\/00313020120038728_bib0190","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1056\/NEJM199801153380303","article-title":"SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma","volume":"338","author":"Kawai","year":"1998","journal-title":"New Engl J Med"},{"key":"10.1080\/00313020120038728_bib0195","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/00000478-199901000-00012","article-title":"Poorly differentiated synovial sarcoma. An analysis of clinical, pathologic and molecular genetic features","volume":"23","author":"Van de Rijn","year":"1999","journal-title":"Am J Surg Pathol"},{"key":"10.1080\/00313020120038728_bib0200","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/ajcp\/112.1.43","article-title":"Absence of SYT-SSX fusion products in soft tissue tumors other than synovial sarcoma","volume":"112","author":"Van de Rijn","year":"1999","journal-title":"Am J Clin Pathol"},{"key":"10.1080\/00313020120038728_bib0205","series-title":"Robbins Pathologic Basis of Disease","year":"1999"},{"key":"10.1080\/00313020120038728_bib0210","first-page":"1323","article-title":"Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of bcl-2","volume":"145","author":"Krajewski","year":"1994","journal-title":"Am J Pathol"},{"key":"10.1080\/00313020120038728_bib0215","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1126\/science.281.5381.1322","article-title":"The bcl-2 protein family: arbiters of cell survival","volume":"281","author":"Adams","year":"1998","journal-title":"Science"},{"key":"10.1080\/00313020120038728_bib0220","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/320084a0","article-title":"Localization of gene for human p53 tumor antigen to band 17 p13","volume":"320","author":"Isobe","year":"1986","journal-title":"Nature"}],"container-title":["Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302516346037?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302516346037?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T17:54:28Z","timestamp":1555005268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031302516346037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001]]}},"alternative-id":["S0031302516346037"],"URL":"https:\/\/doi.org\/10.1080\/00313020120038728","relation":{},"ISSN":["0031-3025"],"issn-type":[{"value":"0031-3025","type":"print"}],"subject":[],"published":{"date-parts":[[2001]]}}}