{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T05:31:48Z","timestamp":1782365508609,"version":"3.54.5"},"reference-count":82,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Postgraduate Medicine"],"published-print":{"date-parts":[[2021,1,2]]},"DOI":"10.1080\/00325481.2020.1823094","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T03:25:00Z","timestamp":1600053900000},"page":"20-27","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":50,"title":["Multisystem effects of COVID-19: a concise review for practitioners"],"prefix":"10.1080","volume":"133","author":[{"given":"Gabrielle","family":"White-Dzuro","sequence":"first","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Zazzeron","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"White-Dzuro","sequence":"additional","affiliation":[{"name":"School of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daren A.","family":"Diiorio","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Low","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin G.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward A.","family":"Bittner","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,11,4]]},"reference":[{"key":"e_1_3_4_2_1","unstructured":"Coronavirus Resource Center. Available from: https:\/\/coronavirus.jhu.edu\/"},{"key":"e_1_3_4_3_1","doi-asserted-by":"crossref","unstructured":"Grasselli G Zangrillo A Zanella A et al. COVID-19 Lombardy ICU Network. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Italy. JAMA. 2020 Apr 28;323(16):1574\u20131581.","DOI":"10.1001\/jama.2020.4031"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_3_4_5_1","unstructured":"Richardson S Hirsch JS Narasimhan M et al. Presenting Characteristics Comorbidities and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020 May 26;323(20):2052\u20132059."},{"issue":"10229","key":"e_1_3_4_6_1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou F","year":"2020","unstructured":"Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054\u20131062.","journal-title":"Lancet"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30937-5"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.04.004"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.120.317015"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.03.037"},{"key":"e_1_3_4_11_1","doi-asserted-by":"crossref","unstructured":"Iba T Levy JH Levi M et al. Coagulopathy of Coronavirus Disease 2019. Crit Care Med. 2020 Sep;48(9):1358\u20131364.","DOI":"10.1097\/CCM.0000000000004458"},{"key":"e_1_3_4_12_1","doi-asserted-by":"crossref","unstructured":"Gattinoni L Coppola S Cressoni M et al. COVID-19 Does Not Lead to a \u201cTypical\u201e Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 May 15;201(10):1299\u20131300.","DOI":"10.1164\/rccm.202003-0817LE"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01768-2020"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6825"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30181-8"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.8539"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03018-x"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-0148-4"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc13184"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14817"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14768"},{"key":"e_1_3_4_22_1","doi-asserted-by":"crossref","unstructured":"Klok FA Kruip MJHA van der Meer NJM et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res. 2020 Jul;191:145\u2013147.","DOI":"10.1016\/j.thromres.2020.04.013"},{"key":"e_1_3_4_23_1","doi-asserted-by":"crossref","unstructured":"Flaczyk A Rosovsky RP Reed CT Bankhead-Kendall BK Bittner EA Chang MG. Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19: implications for clinical practice and future investigations. Crit Care. 2020 Sep 16;24(1):559.","DOI":"10.1186\/s13054-020-03273-y"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1127"},{"key":"e_1_3_4_25_1","doi-asserted-by":"crossref","unstructured":"Toscano G Palmerini F Ravaglia S et al. Guillain-Barr\u00e9 Syndrome Associated with SARS-CoV-2. N Engl J Med. 2020 Jun 25;382(26):2574\u20132576.","DOI":"10.1056\/NEJMc2009191"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2020.116832"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1560"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25915"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.04.024"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.03.062"},{"key":"e_1_3_4_31_1","doi-asserted-by":"crossref","unstructured":"Poyiadji N Shahin G Noujaim D et al. COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: Imaging Features. Radiology. 2020 Aug;296(2):E119\u2013E120.","DOI":"10.1148\/radiol.2020201187"},{"key":"e_1_3_4_32_1","doi-asserted-by":"crossref","unstructured":"Ye M Ren Y Lv T. Encephalitis as a clinical manifestation of COVID-19. Brain Behav Immun. 2020 Aug;88:945\u2013946.","DOI":"10.1016\/j.bbi.2020.04.017"},{"key":"e_1_3_4_33_1","doi-asserted-by":"crossref","unstructured":"Yin R Feng W Wang T Chen G Wu T Chen D Lv T Xiang D. Concomitant neurological symptoms observed in a patient diagnosed with coronavirus disease 2019. J Med Virol. 2020 Apr 15:10.","DOI":"10.1002\/jmv.25888"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2009787"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004961"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-020-01401-7"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-02882-x"},{"issue":"7","key":"e_1_3_4_39_1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S2215-0366(20)30203-0","article-title":"Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic","volume":"7","author":"Rogers JP","year":"2020","unstructured":"Rogers JP, Chesney E, Oliver D, et al. Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic. Lancet Psychiatry. 2020;7(7):611\u2013627.","journal-title":"Lancet Psychiatry"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30287-X"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2020.03.001"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.0950"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2004.04.012"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-020-1643-8"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30116-8"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4812"},{"issue":"7","key":"e_1_3_4_47_1","doi-asserted-by":"crossref","first-page":"e016509","DOI":"10.1161\/JAHA.120.016509","article-title":"Coronavirus disease 2019 (COVID-19): do angiotensin-converting enzyme inhibitors\/angiotensin receptor blockers have a biphasic effect?","volume":"9","author":"Sommerstein R","year":"2020","unstructured":"Sommerstein R, Kochen MM, Messerli FH, et al. Coronavirus disease 2019 (COVID-19): do angiotensin-converting enzyme inhibitors\/angiotensin receptor blockers have a biphasic effect? J Am Heart Assoc. 2020;9(7):e016509.","journal-title":"J Am Heart Assoc"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr2005760"},{"key":"e_1_3_4_49_1","doi-asserted-by":"crossref","unstructured":"Inciardi RM Lupi L Zaccone G Italia L Raffo M Tomasoni D Cani DS Cerini M Farina D Gavazzi E Maroldi R Adamo M Ammirati E Sinagra G Lombardi CM Metra M. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 Jul 1;5(7):819\u2013824.","DOI":"10.1001\/jamacardio.2020.1096"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa286"},{"key":"e_1_3_4_51_1","doi-asserted-by":"crossref","unstructured":"Hua A O'Gallagher K Sado D et al. Life-threatening cardiac tamponade complicating myo-pericarditis in COVID-19. Eur Heart J. 2020 Jun 7;41(22):2130.","DOI":"10.1093\/eurheartj\/ehaa253"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2020.04.048"},{"key":"e_1_3_4_54_1","doi-asserted-by":"crossref","unstructured":"van Damme C Berlingin E Saussez S et al. Acute urticaria with pyrexia as the first manifestations of a COVID-19 infection. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):e300\u2013e301.","DOI":"10.1111\/jdv.16523"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-11-200412070-00010"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.10369"},{"key":"e_1_3_4_57_1","doi-asserted-by":"crossref","unstructured":"Cheung KS Hung IFN Chan PPY et al. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis. Gastroenterology. 2020 Jul;159(1):81\u201395.","DOI":"10.1053\/j.gastro.2020.03.065"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004004"},{"key":"e_1_3_4_59_1","doi-asserted-by":"crossref","unstructured":"Cai Q Huang D Yu H et al. COVID-19: Abnormal liver function tests. J Hepatol. 2020 Sep;73(3):566\u2013574.","DOI":"10.1016\/j.jhep.2020.04.006"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14435"},{"issue":"16","key":"e_1_3_4_61_1","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2020.4326","article-title":"Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State","volume":"323","author":"Arentz M","year":"2020","unstructured":"Arentz M, Yim E, Klaff L, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. JAMA. 2020;323(16):1612.","journal-title":"JAMA"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30079-5"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.005"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30076-X"},{"key":"e_1_3_4_66_1","doi-asserted-by":"crossref","unstructured":"Rubino F Amiel SA Zimmet P et al. New-Onset Diabetes in Covid-19. N Engl J Med. 2020 Aug 20;383(8):789\u2013790.","DOI":"10.1056\/NEJMc2018688"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-009-0109-4"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2016-000379"},{"key":"e_1_3_4_69_1","doi-asserted-by":"crossref","unstructured":"Sattar N McInnes IB McMurray JJV. Obesity Is a Risk Factor for Severe COVID-19 Infection: Multiple Potential Mechanisms. Circulation. 2020 Jul 7;142(1):4\u20136.","DOI":"10.1161\/CIRCULATIONAHA.120.047659"},{"key":"e_1_3_4_70_1","doi-asserted-by":"crossref","unstructured":"Pal R. COVID-19 hypothalamo-pituitary-adrenal axis and clinical implications. Endocrine. 2020 May;68(2):251\u2013252.","DOI":"10.1007\/s12020-020-02325-1"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2004.04.009"},{"key":"e_1_3_4_72_1","doi-asserted-by":"crossref","unstructured":"Brancatella A Ricci D Viola N et al. Subacute Thyroiditis After Sars-COV-2 Infection. J Clin Endocrinol Metab. 2020 Jul 1;105(7):dgaa276.","DOI":"10.1210\/clinem\/dgaa276"},{"key":"e_1_3_4_73_1","unstructured":"BTA\/SFE Statement regarding issues specific to thyroid dysfunction during the COVID -19 pandemic. [cited 2020 May 20]; Available from: https:\/\/www.british-thyroid-association.org\/sandbox\/bta2016\/management-of-thyroid-dysfunction-during-covid-19_final.pdf."},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2020.04.011"},{"key":"e_1_3_4_75_1","doi-asserted-by":"crossref","unstructured":"Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol Venereol. 2020 May;34(5):e212\u2013e213.","DOI":"10.1111\/jdv.16387"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16528"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16472"},{"key":"e_1_3_4_78_1","first-page":"E006","article-title":"Clinical and coagulation characteristics of 7 patients with critical COVID-2019 pneumonia and acro-ischemia","volume":"41","author":"Zhang Y","year":"2020","unstructured":"Zhang Y, Cao W, Xiao M, et al. Clinical and coagulation characteristics of 7 patients with critical COVID-2019 pneumonia and acro-ischemia. Zhonghua Xue Ye Xue Za Zhi. 2020;41:E006.","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.04.018"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2020.04.007"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_3_4_82_1","doi-asserted-by":"crossref","unstructured":"Sun P Qie S Liu Z et al. Clinical characteristics of hospitalized patients with SARS-CoV-2 infection: A single arm meta-analysis. J Med Virol. 2020 Jun;92(6):612\u2013617.","DOI":"10.1002\/jmv.25735"},{"key":"e_1_3_4_83_1","doi-asserted-by":"crossref","unstructured":"Zhu J Ji P Pang J et al. Clinical characteristics of 3062 COVID-19 patients: A meta-analysis. J Med Virol. 2020 Apr 15:10.","DOI":"10.1002\/jmv.25884"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.115.6.1627"},{"issue":"22","key":"e_1_3_4_85_1","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1001\/jama.288.22.2859","article-title":"Paresis acquired in the intensive care unit: a prospective multicenter study","volume":"288","author":"De Jonghe B","year":"2002","unstructured":"De Jonghe B, Sharshar T, Lefaucheur JP, et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA. 2002;288(22):2859\u20132867.","journal-title":"JAMA"}],"container-title":["Postgraduate Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00325481.2020.1823094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T09:47:13Z","timestamp":1696499233000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00325481.2020.1823094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,4]]},"references-count":82,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,2]]}},"alternative-id":["10.1080\/00325481.2020.1823094"],"URL":"https:\/\/doi.org\/10.1080\/00325481.2020.1823094","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.738667086.793587781","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.738667086.793587720","asserted-by":"object"}]},"ISSN":["0032-5481","1941-9260"],"issn-type":[{"value":"0032-5481","type":"print"},{"value":"1941-9260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipgm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-07-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}