{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:46:11Z","timestamp":1771461971870,"version":"3.50.1"},"reference-count":90,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Clinical and Laboratory Investigation"],"published-print":{"date-parts":[[1998,1]]},"DOI":"10.1080\/00365519850186247","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T16:32:26Z","timestamp":1027701146000},"page":"441-458","source":"Crossref","is-referenced-by-count":17,"title":["Are current methods of measurement of erythropoietin (EPO) in human plasma or serum adequate for the diagnosis of polycythaemia vera and the assessment of EPO deficiency?"],"prefix":"10.1080","volume":"58","author":[{"given":"G.","family":"Lindstedt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.A","family":"Lundberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"419 \u2014 34","DOI":"10.1182\/blood.V77.3.419.419","volume":"77","author":"Krantz SB","year":"1991","journal-title":"Blood"},{"key":"CIT0003","first-page":"449 \u2014 89","volume":"72","author":"Jelkmann W. Erythropoietin","year":"1992","journal-title":"Physiol Rev"},{"key":"CIT0004","first-page":"99 \u2014 112","volume":"47","author":"Annable L","year":"1972","journal-title":"The second international reference preparation of erythropoie-tin, human, urinary, for bioassay. Bull World Health Organ"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"459 \u2014 84","DOI":"10.1677\/joe.0.1340459","volume":"134","author":"Storring PL","year":"1992","journal-title":"J Endocrinol"},{"key":"CIT0006","first-page":"121 \u20147","volume":"76","author":"Wide L","year":"1990","journal-title":"Br J Haema-tol"},{"key":"CIT0007","first-page":"535 \u2014 9","volume":"74","author":"Maxwell AP","year":"1990","journal-title":"Erythropoietin gene expres-sion in kidney tissue by in situ hybridization. Br J Haematol"},{"key":"CIT0008","first-page":"78\u2014 86","volume":"13","author":"Koury ST","year":"1993","journal-title":"Semin Nephrol"},{"key":"CIT0009","first-page":"1\u2014 378","volume":"178","author":"Rich IN","year":"1994","journal-title":"Molecular, cellular and developmental biology of erythropoietin and erythropoiesis. Ann NY Acad Sci"},{"issue":"1","key":"CIT0010","first-page":"211 \u2014 6","volume":"8","author":"Spivak JL","year":"1990","journal-title":"Int J Cell Cloning"},{"issue":"6","key":"CIT0011","first-page":"2 \u2014 11","volume":"30","author":"Spivak JL","year":"1993","journal-title":"Semin Hematol"},{"key":"CIT0012","first-page":"54 \u2014 62","volume":"66","author":"Caro J","year":"1988","journal-title":"Contrib Nephrol"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"1301 \u20144","DOI":"10.1111\/j.1532-5415.1993.tb06479.x","volume":"41","author":"Joosten E","year":"1993","journal-title":"J Am Geriatr Soc"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"1412 \u2014 5","DOI":"10.1126\/science.2849206","volume":"242","author":"Goldberg MA.","year":"1988","journal-title":"Science"},{"issue":"3","key":"CIT0015","first-page":"2 \u2014 8","volume":"28","author":"Erslev AJ","year":"1991","journal-title":"Semin Hematol"},{"key":"CIT0016","first-page":"85","volume":"11","author":"Zaroulis CG","year":"1981","journal-title":"Rege AB, Brookins J, Fisher LW. Serum concentrations of erythropoietin measured by radioimmunoassay in hematologic disorders and chronic renal failure. Am J Hematol"},{"key":"CIT0017","first-page":"449","volume":"93","author":"Caro J","year":"1979","journal-title":"Erythropoietin levels in uremic nephric and aneph-ric patients. J Lab Clin Med"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1056\/NEJM199105093241907","volume":"324","author":"Erslev AJ","year":"1991","journal-title":"N Engl J Med"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.me.44.020193.001331","volume":"44","author":"Spivak JL","year":"1993","journal-title":"Annu Rev Med"},{"key":"CIT0020","first-page":"141","volume":"23","author":"Pavlovic-Kentera V","year":"1979","journal-title":"Erythropoietin in patients with ane-mia in rheumatoid arthritis. Scand J Hematol"},{"key":"CIT0021","first-page":"86: 633","author":"Stockemhuber F","year":"1994","journal-title":"Impaired erythro-poietin responsiveness in anaemic rheumatoid arthritis patients: potential relation to immune mechanisms. Clin Sci"},{"key":"CIT0022","first-page":"94","volume":"718","author":"No\u00e9 G","year":"1994","journal-title":"Cir-culating erythropoietin levels in pathophysiological conditions. Ann NY Acad Sci"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF01737420","volume":"68","author":"Barosi G","year":"1994","journal-title":"Ann Hematol"},{"key":"CIT0024","first-page":"1689","volume":"322","author":"Miller CB","year":"1990","journal-title":"Decreased erythropoietin response in patients with the anemia of cancer. N Engl J Med"},{"key":"CIT0025","first-page":"429","volume":"109","author":"Erslev AJ","year":"1987","journal-title":"Erythropoietin titers in anemic, nonuremic patients. J Lab Clin Med"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1365-2265.1982.tb01608.x","volume":"17","author":"Cotes PM","year":"1982","journal-title":"Clin Endocrinol"},{"key":"CIT0027","first-page":"85","volume":"72","author":"Wide L","year":"1989","journal-title":"Circadian rhythm of erythropoietin in human serum. Br J Haematol"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1532-5415.1991.tb05902.x","volume":"39","author":"Powers JS","year":"1991","journal-title":"J Am Geriatr Soc"},{"key":"CIT0029","first-page":"247","volume":"70","author":"Hellebostad M","year":"1988","journal-title":"Serum immu-noreactive erythropoietin in healthy normal chil-dren. Br J Haematol"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1146\/annurev.pa.28.040188.000533","volume":"28","author":"Fisher JW","year":"1988","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/ajh.2830360306","volume":"36","author":"Weber JP","year":"1991","journal-title":"Am J Hematol"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.1365-2141.1992.tb08133.x","volume":"80","author":"Cazzola M","year":"1992","journal-title":"Br J Haematol"},{"key":"CIT0034","first-page":"462","volume":"72","author":"Birgegard G","year":"1989","journal-title":"Marked ery-thropoietin increase before fall in Hb after treatment with cytostatic drugs suggests mechanism other than anaemia for stimulation. Br J Haematol"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1365-2141.1990.tb02602.x","volume":"74","author":"Bowen DT","year":"1990","journal-title":"Br J Hae-matol"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF01648581","volume":"68","author":"Jelkmann W","year":"1990","journal-title":"Klin Wochenschr"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0098-2997(96)88347-6","volume":"17","author":"Messinezy M","year":"1996","journal-title":"Mol Aspects Med"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-0609.1993.tb00611.x","volume":"51","author":"Messinezy M","year":"1993","journal-title":"Eur J Haematol"},{"key":"CIT0039","first-page":"307","volume":"22","author":"Bilgrami S","year":"1995","journal-title":"Semin Oncol"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/j.1365-2141.1994.tb05119.x","volume":"88","author":"Hess G","year":"1994","journal-title":"Br J Haematol"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V83.1.1.1","volume":"83","author":"Prchal JT","year":"1994","journal-title":"Blood"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0002-9343(84)90750-2","volume":"76","author":"Erslev AJ","year":"1984","journal-title":"Am J Med"},{"key":"CIT0043","first-page":"132","volume":"23","author":"Berk PD","year":"1986","journal-title":"Semin Hematol"},{"key":"CIT0044","first-page":"228","volume":"51","author":"Westwood N","year":"1993","journal-title":"Pearson TC. Primary polycythaemia: diagnosis by non-conventional positive criteria. Eur J Haematol"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1182\/blood.V54.4.885.885","volume":"54","author":"Sherwood JB","year":"1979","journal-title":"Blood"},{"key":"CIT0048","first-page":"1472","volume":"122","author":"Sherwood JB","year":"1988","journal-title":"The heterogeneity of circulating human serum erytro-poietin. Endocrinology"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1210\/endo-128-1-440","volume":"128","author":"Lappin TRJ","year":"1991","journal-title":"Endocrinol-ogy"},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2141.1989.tb00263.x","volume":"73","author":"Cotes PM","year":"1989","journal-title":"Br J Haematol"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1182\/blood.V77.6.1164.1164","volume":"77","author":"Rich IN","year":"1991","journal-title":"Blood"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/oxfordjournals.ndt.a092148","volume":"7","author":"Serre AF","year":"1992","journal-title":"Comparison of two radioimmunoas-says for the measurement of serum erythropoietin. Nephrol Dial Transplant"},{"key":"CIT0053","first-page":"663","volume":"83","author":"Bechensteen AG","year":"1993","journal-title":"Cotes PM. Unreliability in immu-noassays of erythropoietin: anomalous estimates with an assay kit. Br J Haematol"},{"key":"CIT0054","first-page":"1680","volume":"21","author":"Deacon R","year":"1993","journal-title":"Exp Hematol"},{"key":"CIT0055","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1749-6632.1994.tb55709.x","volume":"718","author":"Cotes PM","year":"1994","journal-title":"Ann NY Acad Sci"},{"key":"CIT0056","first-page":"427","volume":"50","author":"Cotes PM","year":"1982","journal-title":"I Evidence for the validity of the assay method and the physiological relevance of esti-mates. Br J Haematol"},{"key":"CIT0057","first-page":"624","volume":"99","author":"Garcia JF","year":"1982","journal-title":"J Lab Clin Med"},{"key":"CIT0058","first-page":"829","volume":"100","author":"Rege AB","year":"1982","journal-title":"Fisher JW. A radioimmu-noassay for erythropoietin: serum levels in normal human subjects and patients with hemopoietic dis-orders. J Lab Clin Med"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0022-1759(84)90316-8","volume":"69","author":"Sytkowski AJ","year":"1981","journal-title":"J Immunol Methods"},{"key":"CIT0061","first-page":"177","volume":"185","author":"Matsubara K","year":"1988","journal-title":"Kamachi S.-I, Fukuyshima M, Morii H. Radioimmunoassay for erythropoietin using anti-recombinant erythro-poietin antibody with high affinity. Clin Chim Acta"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1992.tb02999.x"},{"key":"CIT0063","first-page":"431","volume":"80","author":"Ma DDF","year":"1992","journal-title":"A.-Q, Dowton LA, Lau KS, Wu Z.-H, Ueda M. Assessment of an EIA for measuring human serum erythropoietin as compared with RIA and an in-vitro bioassay. Br J Haematol"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1182\/blood.V74.2.622.622","volume":"74","author":"Wognum AW","year":"1989","journal-title":"Blood"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1093\/clinchem\/38.9.1752","volume":"38","author":"Tanebe M","year":"1992","journal-title":"Clin Chem"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-2141.1992.tb08134.x","volume":"80","author":"Noe G","year":"1992","journal-title":"Br J Haematol"},{"key":"CIT0067","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/000456329102800405","volume":"28","author":"Pressac M","year":"1991","journal-title":"Ann Clin Bio-chem"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1093\/clinchem\/38.5.758","volume":"38","author":"Andre M","year":"1992","journal-title":"Clin Chem"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0009-9120(93)90024-Z","volume":"26","author":"Goldberg MA","year":"1993","journal-title":"Clin Biochem"},{"key":"CIT0070","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1093\/clinchem\/36.10.1731","volume":"36","author":"Schlageter MH","year":"1990","journal-title":"Clin Chem"},{"key":"CIT0071","first-page":"237","volume":"32","author":"Najean Y","year":"1990","journal-title":"Nouv Rev Fr Hematol"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1182\/blood.V81.4.1067.1067","volume":"81","author":"Beguin Y","year":"1993","journal-title":"Blood"},{"key":"CIT0073","first-page":"333","volume":"10","author":"Urabe A","year":"1992","journal-title":"Serum erythropoietin titers in hematological malignancies and related diseases. Int J Cell Cloning"},{"key":"CIT0074","first-page":"229","volume":"37","author":"Jelkmann W","year":"1991","journal-title":"Klin Lab"},{"key":"CIT0075","first-page":"601","volume":"126","author":"Krafte-Jacobs B","year":"1995","journal-title":"Plasma ery-thropoietin reference ranges in children. J Pediatr"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1055\/s-0029-1235437","volume":"116","author":"Jelkmann W","year":"1991","journal-title":"Methodik, Indikation und Interpretation der Messdaten. Dtsch Med Wochenschr"},{"key":"CIT0078","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1365-2257.1991.tb00268.x","volume":"13","author":"Kendall RG","year":"1991","journal-title":"Clin Lab Haema-tol"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF01748163","volume":"66","author":"Eckardt KU","year":"1988","journal-title":"Klin Wochenschr"},{"key":"CIT0080","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/clinchem\/41.3.367","volume":"41","author":"Spencer CA","year":"1995","journal-title":"Clin Chem"},{"key":"CIT0081","first-page":"117","volume":"70","author":"Lappin TRJ","year":"1988","journal-title":"Comparison of the mouse spleen assay and a radioimmunoassay for the measurement of serum erythropoietin. Br J Haematol"},{"key":"CIT0082","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.1988.03410010073038","volume":"260","author":"Kickler TS","year":"1988","journal-title":"JAMA"},{"key":"CIT0083","first-page":"111","volume":"55","author":"Maeda H","year":"1992","journal-title":"The effect of phlebotomy on serum erythropoietin levels in normal healthy subjects. Int J Hematol"},{"key":"CIT0084","first-page":"217 \u2014 220","volume":"17","author":"Messinezy M.","year":"1995","journal-title":"Clin Lab Haematol"},{"key":"CIT0085","first-page":"969 \u2014 75","volume":"38","author":"Mason-Garcia M","year":"1990","journal-title":"Development of a new radioimmunoas-say for erythropoietin using recombinant erythro-poietin. Kidney Int"},{"key":"CIT0086","first-page":"100 \u2014 5","volume":"76","author":"Kientsch-Engel R","year":"1989","journal-title":"A. Methods for measuring erythropoietin and ery-thropoietin antibodies using ELISA technique. In: Baldamus CA, Scigalla P, Wieczorek L, Koch KM, editors. Erytropoietin: From molecular structure to clinical application. Contrib Nephrol"},{"key":"CIT0087","first-page":"255","volume":"8","author":"Kientsch-Engel R","year":"1990","journal-title":"New enzyme-linked immunosorbent assay methods for measurement of erythropoietin levels and erythropoietin antibodies. Blood Purif"},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"1491 \u20145","DOI":"10.1093\/clinchem\/32.8.1491","volume":"32","author":"Boscato LM","year":"1986","journal-title":"Clin Chem"},{"key":"CIT0089","first-page":"108 \u2014 115","volume":"15","author":"Levinson SS","year":"1992","journal-title":"J Clin Immunoassay"},{"key":"CIT0090","doi-asserted-by":"crossref","first-page":"429 \u2014 32","DOI":"10.1530\/eje.0.1300429","volume":"130","author":"Lindstedt G","year":"1994","journal-title":"Eur J Endocrinol"},{"key":"CIT0091","doi-asserted-by":"crossref","first-page":"44 \u2014 7","DOI":"10.7326\/0003-4819-94-1-44","volume":"94","author":"Koeffler HP","year":"1981","journal-title":"Ann Intern Med"},{"key":"CIT0092","doi-asserted-by":"crossref","first-page":"283 \u2014 7","DOI":"10.1056\/NEJM198607313150503","volume":"315","author":"Cotes PM","year":"1986","journal-title":"N Engl J Med"},{"key":"CIT0093","first-page":"113 \u2014 20","volume":"44","author":"Djulbegovic B","year":"1991","journal-title":"A new algo-rithm for the diagnosis of polycythemia. Am Fam Physician"},{"key":"CIT0094","first-page":"278","volume":"60","author":"Carneskog J","year":"1998","journal-title":"Plasma erythropoietin by high-detect-ability immunoradiometric assay in untreated and treated patients with polycythaemia vera and essential thrombocythaemia. Eur J Haematol"},{"key":"CIT0096","first-page":"495 \u2014 6","volume":"46","author":"Aakvaag A","year":"1986","journal-title":"Scand J Clin Lab Invest"},{"key":"CIT0097","first-page":"99 \u2014 101","volume":"43","author":"Aakvaag A","year":"1983","journal-title":"Diagnostic reagent kits\u2014embarras de richesse. Scand J Clin Lab Invest"}],"container-title":["Scandinavian Journal of Clinical and Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/00365519850186247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T02:06:38Z","timestamp":1583287598000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/00365519850186247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":90,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1080\/00365519850186247"],"URL":"https:\/\/doi.org\/10.1080\/00365519850186247","relation":{},"ISSN":["0036-5513","1502-7686"],"issn-type":[{"value":"0036-5513","type":"print"},{"value":"1502-7686","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}