{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T16:45:44Z","timestamp":1749573944605},"reference-count":88,"publisher":"Informa UK Limited","issue":"234","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Gastroenterology"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1080\/003655201753265406","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:32:29Z","timestamp":1027697549000},"page":"15-21","source":"Crossref","is-referenced-by-count":7,"title":["Recent Developments in Helicobacter pylori Vaccination"],"prefix":"10.1080","volume":"36","author":[{"given":"J. G.","family":"Kusters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/oxfordjournals.epirev.a036078","volume":"13","author":"Taylor DN","year":"1991","journal-title":"Epidemiol Rev"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)01501-2"},{"key":"CIT0004","first-page":"177","volume":"61","author":"Anonymous","year":"1994","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1128\/CMR.10.4.720","volume":"10","author":"Dunn BE","year":"1997","journal-title":"Helicobacter pylori. Clin Microbiol Rev"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1046\/j.1523-5378.1999.99311.x","volume":"4","author":"Rupnow MF","year":"1999","journal-title":"Helicobacter"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1136\/gut.48.1.10","volume":"48","author":"Macdonald TT","year":"2001","journal-title":"Gut"},{"key":"CIT0008","first-page":"536","volume":"6","author":"Fox JG","year":"2000","journal-title":"Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces Helicobacter -induced gastric atrophy. Nature Med"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1038\/35006081"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s005350050232","volume":"34","author":"Sugiyama T","year":"1999","journal-title":"J Gastroenterol"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1136\/gut.43.1.7","volume":"43","author":"Crabtree J","year":"1998","journal-title":"Gut"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/clinids\/11.6.853","volume":"11","author":"Hone D","year":"1989","journal-title":"Rev Infect Dis"},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.2174\/1381612003399086","volume":"6","author":"Ernst PB","year":"2000","journal-title":"Curr Pharm Des"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1523-5378.1997.tb00061.x","volume":"2","author":"Whary MT","year":"1997","journal-title":"Helicobacter"},{"key":"CIT0015","first-page":"850","volume":"16","author":"Guy B","year":"1998","journal-title":"Systemic Immunization with urease protects mice against Helicobacter pylori infection. Vaccine"},{"key":"CIT0016","first-page":"181","volume":"241","author":"Blanchard TG","year":"1999","journal-title":"Host response and vaccine development to Helicobacter pylori infection. Curr Topics Microbiol Immunol"},{"key":"CIT0017","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1016\/S0264-410X(00)00553-3","volume":"19","author":"Pizza M","year":"2001","journal-title":"Vaccine"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1128\/IAI.67.9.4539-4544.1999","volume":"67","author":"Jiang B","year":"1999","journal-title":"Infect Immun"},{"key":"CIT0019","first-page":"460","volume":"16","author":"Gomez-Duarte OG","year":"1998","journal-title":"producing urease subunits A and B. Vaccine"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1128\/IAI.66.2.581-586.1998","volume":"66","author":"Corthesy-Theulaz IE","year":"1998","journal-title":"A and B subunits Infect Immun"},{"key":"CIT0021","first-page":"186","volume":"336","author":"Pallen MJ","year":"1990","journal-title":"Vaccination against Helicobacter pylori urease Lancet"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)91111-8"},{"key":"CIT0023","first-page":"1027","volume":"25","author":"Ramirez-Ramos A","year":"1997","journal-title":"Rapid recurrence of Helicobacter pylori infection in Peruvian patients after successful eradication. Gastrointestinal Physiology Working Group of the Universidad Peruana Cayetano Heredia and the Johns Hopkins University. Clin Infect Dis"},{"key":"CIT0024","first-page":"336","volume":"117","author":"Rowland M","year":"1999","journal-title":"Low rates of Helicobacter pylori reinfection in children. Gastroenterology"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/0950-3528(95)90042-X","volume":"9","author":"Feldman RA","year":"1995","journal-title":"Baillieres Clin Gastroenterol"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0140-6736(93)91327-I","volume":"342","author":"Thomas JE","year":"1993","journal-title":"Lancet"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/00005176-199808000-00010","volume":"27","author":"Perri F","year":"1998","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1086\/515105","volume":"28","author":"Malaty HM","year":"1999","journal-title":"Clin Infect Dis"},{"key":"CIT0029","first-page":"631","volume":"88","author":"Tindberg Y","year":"1999","journal-title":"Clinical symptoms and social factors in a cohort of children spontaneously clearing Helicobacter pylori infection. Acta Paediatr"},{"key":"CIT0030","first-page":"84","volume":"25","author":"Kehrt R","year":"1997","journal-title":"infection in Nicaraguan children with persistent diarrhea, diagnosed by the 13C-urea breath test. J Pediatr Gastroenterol Nutr"},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1086\/515376","volume":"178","author":"Kumagai T","year":"1998","journal-title":"J Infect Dis"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1128\/IAI.59.7.2359-2363.1991","volume":"59","author":"Czinn SJ","year":"1991","journal-title":"Infect Immun"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/0016-5085(90)91156-Z","volume":"99","author":"Lee A","year":"1990","journal-title":"Gastroenterology"},{"key":"CIT0034","first-page":"181","volume":"46","author":"Seidel KE","year":"1999","journal-title":"Zentralbl Veterinarmed"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1439-0442.1996.tb00457.x","volume":"43","author":"Happonen I","year":"1996","journal-title":"Zentralbl Veterinarmed A"},{"key":"CIT0036","first-page":"637","volume":"11","author":"Czinn SJ","year":"1993","journal-title":"Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization. Vaccine"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1994.tb02136.x"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1126\/science.7886456","volume":"267","author":"Marchetti M","year":"1995","journal-title":"Science"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/S0016-5085(97)70155-0","volume":"112","author":"Lee A","year":"1997","journal-title":"Gastroenterology"},{"key":"CIT0040","first-page":"717","volume":"8","author":"Michetti P","year":"1996","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"CIT0041","first-page":"1120","volume":"339","author":"Chen M","year":"1992","journal-title":"Immunisation against gastric Helicobacter infection in a mouse\/Helicobacter felis model. Lancet"},{"key":"CIT0042","doi-asserted-by":"crossref","first-page":"3594","DOI":"10.1128\/IAI.62.8.3594-3597.1994","volume":"62","author":"Lee A","year":"1994","journal-title":"Infect Immun"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/infdis\/172.1.161","volume":"172","author":"Lee CK","year":"1995","journal-title":"J Infect Dis"},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1007\/BF02088757","volume":"41","author":"Stadtlander CT","year":"1996","journal-title":"Dig Dis Sci"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1046\/j.1365-2567.1998.00482.x","volume":"94","author":"Blanchard TG","year":"1998","journal-title":"Immunology"},{"key":"CIT0046","first-page":"123","volume":"92","author":"De Magistris MT","year":"1998","journal-title":"heat-labile enterotoxin following intranasal, oral and intravaginal immunization. Dev Biol Stand"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1084\/jem.188.12.2277","volume":"188","author":"Ermak TH","year":"1998","journal-title":"J Exp Med"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0264-410X(97)00153-9","volume":"16","author":"Marchetti M","year":"1998","journal-title":"Vaccine"},{"key":"CIT0049","first-page":"1130","volume":"17","author":"Guy B","year":"1999","journal-title":"Comparison between targeted and untargeted systemic immunizations with adjuvanted urease to cure Helicobacter pylori infection in mice. Vaccine"},{"key":"CIT0050","first-page":"1399","volume":"178","author":"Eaton KA","year":"1998","journal-title":"Vaccination of gnotobiotic piglets against Helicobacter pylori. J Infect Dis"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1046\/j.1523-5378.1999.09046.x","volume":"4","author":"Kim SY","year":"1999","journal-title":"Helicobacter"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/S0264-410X(98)00365-X","volume":"17","author":"Lee CK","year":"1999","journal-title":"Vaccine"},{"key":"CIT0053","first-page":"72","volume":"32","author":"Park EJ","year":"2000","journal-title":"The mucosal adjuvanticity of two nontoxic mutants of Escherichia coli heatlabile enterotoxin varies with immunization routes. Exp Molec Med"},{"key":"CIT0054","first-page":"2775","volume":"68","author":"Weltzin R","year":"2000","journal-title":"Parenteral adjuvant activities of Escherichia coli heat-labile toxin and its B subunit for immunization of mice against gastric Helicobacter pylori infection. Infect Immun"},{"key":"CIT0055","doi-asserted-by":"crossref","unstructured":"Ferrero RL, Thiberge JM, Huerre M, Labigne A. Recombinant antigens prepared from the urease subunits ofHelicobacterspp. evidence of protection in a mouse model of gastric infection. Infect Immun 1994;62: 4981\u20139.","DOI":"10.1128\/IAI.62.11.4981-4989.1994"},{"key":"CIT0056","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1084\/jem.191.9.1467","volume":"191","author":"Satin B","year":"2000","journal-title":"J Exp Med"},{"key":"CIT0057","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1128\/IAI.65.11.4615-4619.1997","volume":"65","author":"Manetti R","year":"1997","journal-title":"Infect Immun"},{"key":"CIT0058","doi-asserted-by":"crossref","first-page":"6499","DOI":"10.1073\/pnas.92.14.6499","volume":"92","author":"Ferrero RL","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"4668","DOI":"10.1128\/IAI.65.11.4668-4674.1997","volume":"65","author":"Radcliff FJ","year":"1997","journal-title":"vaccination. Infect Immun"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/S0264-410X(98)00387-9","volume":"17","author":"Myers GA","year":"1999","journal-title":"Vaccine"},{"key":"CIT0061","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(84)91816-6","volume":"1","author":"Marshall BJ","year":"1984","journal-title":"Lancet"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1038\/41483"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/16495","volume":"397","author":"Alm RA","year":"1999","journal-title":"Nature"},{"key":"CIT0064","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1007\/s001099900067","volume":"77","author":"Alm RA","year":"1999","journal-title":"J Molec Med"},{"key":"CIT0065","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0966-842X(97)01164-5","volume":"5","author":"Berg DE","year":"1997","journal-title":"Trends Microbiol"},{"key":"CIT0066","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1128\/MMBR.63.3.642-674.1999","volume":"63","author":"Marais A","year":"1999","journal-title":"Microbiol Molec Biol Rev"},{"key":"CIT0067","first-page":"675","volume":"63","author":"Doig P","year":"1999","journal-title":"Helicobacter pylori physiology predicted from genomic comparison of two strains. Microbiol Molec Biol Rev"},{"key":"CIT0068","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0140-6736(94)90032-9","volume":"343","author":"Doidge C","year":"1994","journal-title":"Lancet"},{"key":"CIT0069","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0016-5085(95)90275-9","volume":"109","author":"Corth\u00e9sy-Theulaz I","year":"1995","journal-title":"infection in mice. Gastroenterology"},{"key":"CIT0070","first-page":"4996","volume":"65","author":"Ghiara P","year":"1997","journal-title":"Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection. Infect Immun"},{"key":"CIT0071","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/0016-5085(90)91016-Y","volume":"99","author":"Fox JG","year":"1990","journal-title":"gastritis in humans. Gastroenterology"},{"key":"CIT0072","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1053\/gast.1996.v110.pm8964402","volume":"110","author":"Cuenca R","year":"1996","journal-title":"Gastroenterology"},{"key":"CIT0073","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.1128\/IAI.66.9.4340-4346.1998","volume":"66","author":"Dubois A","year":"1998","journal-title":"Infect Immun"},{"key":"CIT0074","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S0016-5085(99)70063-6","volume":"116","author":"Michetti P","year":"1999","journal-title":"Gastroenterology"},{"key":"CIT0075","first-page":"1630","volume":"347","author":"Kreiss C","year":"1996","journal-title":"Safety of oral immunisation with recombinant urease in patients with Helicobacter pylori infection [Letter]. Lancet"},{"key":"CIT0076","first-page":"1848","volume":"113","author":"Mohammadi M","year":"1997","journal-title":"infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load. Gastroenterology"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1128\/IAI.69.3.1714-1721.2001","volume":"69","author":"Lucas B","year":"2001","journal-title":"Infect Immun"},{"key":"CIT0078","doi-asserted-by":"crossref","first-page":"4729","DOI":"10.4049\/jimmunol.156.12.4729","volume":"156","author":"Mohammadi M","year":"1996","journal-title":"J Immunol"},{"key":"CIT0079","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/infdis\/172.1.161","volume":"172","author":"Lee CK","year":"1995","journal-title":"J Infect Dis"},{"key":"CIT0080","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0016-5085(98)70261-6","volume":"115","author":"Saldinger PF","year":"1998","journal-title":"Gastroenterology"},{"key":"CIT0081","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-2036.2001.00923.x","volume":"15","author":"Armuzzi A","year":"2001","journal-title":"Aliment Pharmacol Ther"},{"key":"CIT0082","doi-asserted-by":"crossref","first-page":"4573","DOI":"10.1128\/AEM.64.11.4573-4580.1998","volume":"64","author":"Coconnier MH","year":"1998","journal-title":"Applied Environ Microbiol"},{"key":"CIT0083","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s002840010175","volume":"42","author":"Lorca GL","year":"2001","journal-title":"Curr Microbiol"},{"key":"CIT0084","first-page":"475","volume":"79","author":"Midolo PD","year":"1995","journal-title":"NCTC 11637 by organic acids and lactic acid bacteria. J Appl Bacteriol"},{"key":"CIT0085","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/jac\/47.5.709","volume":"47","author":"Sakamoto I","year":"2001","journal-title":"J Antimicrobial Chemother"},{"key":"CIT0086","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0952-7915(97)80101-X","volume":"9","author":"Telford JL","year":"1997","journal-title":"Curr Opin Immunol"},{"key":"CIT0087","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1136\/bmj.316.7143.1507","volume":"316","author":"Blaser MJ","year":"1998","journal-title":"BMJ"},{"key":"CIT0088","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/S0016-5085(97)70024-6","volume":"112","author":"Labenz J","year":"1997","journal-title":"Gastroenterology"},{"key":"CIT0089","first-page":"588","volume":"58","author":"Chow WH","year":"1998","journal-title":"Cancer Res"}],"container-title":["Scandinavian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/003655201753265406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T15:38:42Z","timestamp":1682177922000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/003655201753265406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":88,"journal-issue":{"issue":"234","published-online":{"date-parts":[[2009,7,8]]},"published-print":{"date-parts":[[2001,1]]}},"alternative-id":["10.1080\/003655201753265406"],"URL":"https:\/\/doi.org\/10.1080\/003655201753265406","relation":{},"ISSN":["0036-5521","1502-7708"],"issn-type":[{"value":"0036-5521","type":"print"},{"value":"1502-7708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}