{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:13:06Z","timestamp":1772809986869,"version":"3.50.1"},"reference-count":22,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Journal of Urology and Nephrology"],"published-print":{"date-parts":[[2002,1,1]]},"DOI":"10.1080\/003655902762467549","type":"journal-article","created":{"date-parts":[[2003,2,20]],"date-time":"2003-02-20T22:31:44Z","timestamp":1045780304000},"page":"405-413","source":"Crossref","is-referenced-by-count":37,"title":["Parenteral Estrogen versus Combined Androgen Deprivation in the Treatment of Metastatic Prostatic Cancer - Scandinavian Prostatic Cancer Group (SPCG) Study No. 5"],"prefix":"10.1080","volume":"36","author":[{"given":"Per Olov","family":"Hedlund","sequence":"first","affiliation":[{"name":"Department of Urology, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martti","family":"Ala-Opas","sequence":"additional","affiliation":[{"name":"Department of Urology, Kuopio University Hospital, Kuopio, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Einar","family":"Brekkan","sequence":"additional","affiliation":[{"name":"Department of Urology, Uppsala Academic Hospital, Uppsala, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Erik","family":"Damber","sequence":"additional","affiliation":[{"name":"Department of Urology, Sahlgrens University Hospital, Gothenburg, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Damber","sequence":"additional","affiliation":[{"name":"Department of Urology, Oncologic Center, Umea\u02daUniversity, Umea\u02da, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inger","family":"Hagerman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Huddinge Hospital, Huddinge, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svein","family":"Haukaas","sequence":"additional","affiliation":[{"name":"Diakonissehjemmet Hospital, Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Henriksson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Huddinge Hospital, Huddinge, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Urology, Rigshospitalet, Copenhagen, Denmark, 10Research Laboratory for Reproductive Health, Karolinska Hospital, Stockholm, Sweden and the Departments of Urology, 11Herlev University Hospital, Herlev, Denmark, 12Helsinki University Hospital, Helsinki, Finland, 13Stavanger Hospital, Stavanger, Norway and 14Norrk\u00f6ping Hospital, Norrk\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5ke","family":"Pousette","sequence":"additional","affiliation":[{"name":"Research Laboratory for Reproductive Health, Karolinska Hospital, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Urology, Herlev University Hospital, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaakko","family":"Salo","sequence":"additional","affiliation":[{"name":"Department of Urology, Helsinki University Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigmund","family":"Vaage","sequence":"additional","affiliation":[{"name":"Department of Urology, Stavanger Hospital, Stavanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eberhard","family":"Varenhorst","sequence":"additional","affiliation":[{"name":"Department of Urology, Norrk\u00f6ping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,9]]},"reference":[{"key":"CIT0001","first-page":"282","volume":"65","author":"Henriksson P","year":"1990","journal-title":"Effect of parenteral oestrogen on the coagulation system in patients with prostatic carcinoma. Br J Urol"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1989.tb05946.x"},{"key":"CIT0003","first-page":"171","volume":"28","author":"Lukkarinen O","year":"1994","journal-title":"Comparison of a long-acting LHRH agonist and polyestradiol phosphate in the treatment of advanced prostatic carcinoma. Scand J Urol Nephrol"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/pros.2990140211","volume":"14","author":"Stege R","year":"1989","journal-title":"Prostate"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0045(19990701)40:2<76::AID-PROS2>3.0.CO;2-Q"},{"key":"CIT0006","first-page":"257","volume":"13","author":"Henriksson P","year":"1988","journal-title":"Cardiovascular follow-up of patients with prostatic cancer treated with single-drug polyestradiol phosphate. Prostate"},{"key":"CIT0007","first-page":"328","volume":"55","author":"Hedlund PO","year":"2000","journal-title":"The Scandinavian Prostatic Cancer Group (SPCG)-5 Trial Study. Urology"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.3109\/00365597109133601"},{"key":"CIT0009","unstructured":"Mostofi FK, Sesterhenn IA, Sobin LH. In: Histologic typing of prostate tumors. Geneva, Switzerland: edn World Health Organization, 1980: 17\u201321."},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/cncr.1990.66.s5.1017","volume":"66","author":"Soloway MS","year":"1990","journal-title":"Cancer"},{"key":"CIT0011","unstructured":"Andersson L. Design of clinical trials on prostate cancer. Urology 1997; 49 (Suppl 4A): 39\u201345."},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810101)47:1<207::AID-CNCR2820470134>3.0.CO;2-6"},{"key":"CIT0013","first-page":"203","volume":"7","author":"Fr\u00f6din T","year":"1985","journal-title":"Measurement of skin blood-flow and water evaporation as a means of objectively assessing hot flushes after orchidectomy in patients with prostatic cancer. Prostate"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1007\/BF01068419"},{"key":"CIT0015","first-page":"63","volume":"82","author":"Mikkola AK","year":"1998","journal-title":"Parenteral polyestradiol phosphate vs orchidectomy in the treatment of advanced prostatic cancer. Efficacy and cardiovascular complications: a 2-year follow-up report of a national, prospective prostatic cancer study. Finnprostate Group. Br J Urol"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF02985194","volume":"3","author":"Henriksson P","year":"1989","journal-title":"Med Oncol Tumor Pharmacother"},{"key":"CIT0017","first-page":"111","volume":"49","author":"Blomback M","year":"1988","journal-title":"Changes in blood coagulation and fibrinolysis in patients on different treatment regimens for prostatic cancer. Predictors for cardiovascular complications? Thromb Res"},{"key":"CIT0018","first-page":"103","volume":"55","author":"Hedlund PO","year":"1980","journal-title":"Cardiovascular complications to treatment of prostate cancer with estramustine phosphate (Estracyt (Etp or conventional estrogen. Scand J Urol Nephrol Suppl"},{"key":"CIT0019","first-page":"93","volume":"114","author":"Eisen M","year":"1975","journal-title":"Inhibition of platelet aggregation caused by estrogen treatment in patients with carcinoma of the prostate. J Urol"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198411153112004"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66670-9"},{"key":"CIT0022","first-page":"517","volume":"166","author":"Spetz AC","year":"2001","journal-title":"Prospective evaluation of hot flushes during treatment with parenteral estrogen or complete Scand J Urol Nephrol 36 androgen ablation for metastatic carcinoma of the prostate. J Urol"}],"container-title":["Scandinavian Journal of Urology and Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/003655902762467549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T19:19:26Z","timestamp":1682450366000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/003655902762467549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1,1]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2002,1,1]]}},"alternative-id":["10.1080\/003655902762467549"],"URL":"https:\/\/doi.org\/10.1080\/003655902762467549","relation":{},"ISSN":["0036-5599","1651-2065"],"issn-type":[{"value":"0036-5599","type":"print"},{"value":"1651-2065","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1,1]]}}}