{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T06:36:13Z","timestamp":1780554973947,"version":"3.54.1"},"reference-count":14,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Xenobiotica"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.1080\/004982500237839","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T16:26:58Z","timestamp":1027700818000},"page":"71-80","source":"Crossref","is-referenced-by-count":25,"title":["Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes"],"prefix":"10.1080","volume":"30","author":[{"family":"N. Ishiguro, C. Senda, W. Kishimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2009,8,27]]},"reference":[{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.3109\/00498259509061850"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.3109\/00498259409043254"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/0165-6147(92)90107-H","volume":"13","author":"GONZALEZ F. J","year":"1992","journal-title":"Trends in Pharmacological Science"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3109\/03602539409029789","volume":"26","author":"GONZALEZ F. J.","year":"1991","journal-title":"Drug Metabolism Reviews"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0378-4274(94)90156-2","volume":"70","author":"GUENGERICH F. P","year":"1994","journal-title":"Toxicology Letters"},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1021\/tx00022a001","volume":"4","author":"GUENGERICH F. P.","year":"1991","journal-title":"Chemical Research in Toxicology"},{"key":"CIT0016","first-page":"1","volume":"22","author":"HORAI Y.","year":"1988","journal-title":"Rational Drug Therapy"},{"key":"CIT0018","first-page":"904","volume":"28","author":"JAucx R.","year":"1978","journal-title":"Arzneimittel forschung"},{"key":"CIT0019","first-page":"273","volume":"98","author":"KisHimoro W.","year":"1997","journal-title":"Research Communications in Molecular Pathology and Pharmacology"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3109\/03602538708998300","volume":"18","author":"MURRAY M","year":"1987","journal-title":"Drug Metabolism Reviews"},{"key":"CIT0021","first-page":"127","volume":"9","author":"NAGAOKA S.","year":"1981","journal-title":"Japanese Pharmacology and Therapeutics"},{"key":"CIT0022","first-page":"154","volume":"23","author":"NEWTON D. J.","year":"1995","journal-title":"Drug Metabolism and Disposition"},{"key":"CIT0023","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3999\/jscpt.8.25","volume":"8","author":"SEKI T.","year":"1977","journal-title":"Japanese Journal of Clinical Pharmacology and Therapeutics"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0140-6736(84)90283-6","author":"WUNANDS W. J","year":"1984","journal-title":"Lancet"}],"container-title":["Xenobiotica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/004982500237839","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T06:49:18Z","timestamp":1497509358000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/004982500237839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,8,27]]},"published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1080\/004982500237839"],"URL":"https:\/\/doi.org\/10.1080\/004982500237839","relation":{},"ISSN":["0049-8254","1366-5928"],"issn-type":[{"value":"0049-8254","type":"print"},{"value":"1366-5928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}